Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jack SA"'
Publikováno v:
Journal of Assisted Reproduction & Genetics; Oct2023, Vol. 40 Issue 10, p2385-2390, 6p
Autor:
Amanda Worker, Hadley Mahon, Jack Sams, Freya Boardman-Pretty, Elena Marchini, Rand Dubis, Alan Warren, Jez Stockdale, Jyothika Kumar, Elizabeth Varones, Daniel Ollerenshaw, Calum Grant, Peter Fish, Richard J. Kelly
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Paroxysmal Nocturnal Haemoglobinuria (PNH) is an ultra-rare, acquired disorder that is challenging to diagnose due to varied symptoms, heterogeneous patient presentations, and lack of awareness among healthcare professionals. This
Externí odkaz:
https://doaj.org/article/e788d01ac5f04052a0b45d8c9f5b7321
Systematic literature review of the somatic comorbidities experienced by adults with phenylketonuria
Autor:
Kaleigh B. Whitehall, Sarah Rose, Gillian E. Clague, Kirsten K. Ahring, Deborah A. Bilder, Cary O. Harding, Álvaro Hermida, Anita Inwood, Nicola Longo, François Maillot, Ania C. Muntau, André L. S. Pessoa, Júlio C. Rocha, Fran Rohr, Serap Sivri, Jack Said, Sheun Oshinbolu, Gillian C. Sibbring
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-51 (2024)
Abstract Background Phenylketonuria (PKU) is an inborn error of phenylalanine (Phe) metabolism that, if untreated, causes Phe accumulation in the brain leading to neurophysiologic alterations and poor outcomes. Lifelong management centers on dietary
Externí odkaz:
https://doaj.org/article/2dc70781578846fc93ab92e719142d46
Autor:
Samira Salihovic, Niklas Nyström, Charlotte Bache-Wiig Mathisen, Robert Kruse, Christine Olbjørn, Svend Andersen, Alexandra J. Noble, Maria Dorn-Rasmussen, Igor Bazov, Gøri Perminow, Randi Opheim, Trond Espen Detlie, Gert Huppertz-Hauss, Charlotte R. H. Hedin, Marie Carlson, Lena Öhman, Maria K. Magnusson, Åsa V. Keita, Johan D. Söderholm, Mauro D’Amato, Matej Orešič, Vibeke Wewer, Jack Satsangi, Carl Mårten Lindqvist, Johan Burisch, Holm H. Uhlig, Dirk Repsilber, Tuulia Hyötyläinen, Marte Lie Høivik, Jonas Halfvarson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples from a discovery cohort of incident treatment-naï
Externí odkaz:
https://doaj.org/article/8a477108fc6e4a34a2cccb17d607374e
Autor:
Jack Sauvage, Safa Moustefaoui, Stefano Fiorentini, Maelys Venet, Solveig Fadnes, Lasse Lovastakken, Olivier Villemain, Sébastien Salles
Publikováno v:
Frontiers in Physics, Vol 12 (2024)
IntroductionNumerous studies have shown that natural mechanical waves have the potential to assess the elastic properties of the myocardium. When the Aortic and Mitral valves close, a shear wave is produced, which provides insights into tissue stiffn
Externí odkaz:
https://doaj.org/article/1c141dc2ffd449c4aa972916fce26aa6
Autor:
Jie Chen, Han Zhang, Tian Fu, Jianhui Zhao, Jan Krzysztof Nowak, Rahul Kalla, Judith Wellens, Shuai Yuan, Alexandra Noble, Nicholas T. Ventham, Malcolm G. Dunlop, Jonas Halfvarson, Ren Mao, Evropi Theodoratou, Jack Satsangi, Xue Li
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105443- (2024)
Summary: Background: This study aims to confirm the associations of air pollution with ulcerative colitis (UC) and Crohn's disease (CD); to explore interactions with genetics and lifestyle; and to characterize potential epigenetic mechanisms. Methods
Externí odkaz:
https://doaj.org/article/2f7b2d8722784ab88ccf8c0ceb2b28a7
Autor:
Simone Dallari, Vicky Martinez Pazos, Juan Munoz Eusse, Judith Wellens, Craig Thompson, Jean-Frederic Colombel, Jack Satsangi, Ken Cadwell, Serre-Yu Wong, ICARUS-IBD Working Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract While differential antibody responses SARS-CoV-2 in patients with inflammatory bowel disease (IBD) receiving infliximab and vedolizumab are well-characterized, the immune pathways underlying these differences remain unknown. Prior to COVID-1
Externí odkaz:
https://doaj.org/article/d097121319674b2b89b25aece89b4326
Autor:
Han Zhang, Rahul Kalla, Jie Chen, Jianhui Zhao, Xuan Zhou, Alex Adams, Alexandra Noble, Nicholas T. Ventham, Judith Wellens, Gwo-Tzer Ho, Malcolm G. Dunlop, Jan Krzysztof Nowak, Yuan Ding, Zhanju Liu, Jack Satsangi, Evropi Theodoratou, Xue Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian randomization study are first conducted to evaluate the association between smoking be
Externí odkaz:
https://doaj.org/article/04a74e10927f428d84730e560996c873
Autor:
Gail D. Lewis, Guangmin Li, Jun Guo, Shang-Fan Yu, Carter T. Fields, Genee Lee, Donglu Zhang, Peter S. Dragovich, Thomas Pillow, BinQing Wei, Jack Sadowsky, Douglas Leipold, Tim Wilson, Amrita Kamath, Michael Mamounas, M. Violet Lee, Ola Saad, Voleak Choeurng, Alexander Ungewickell, Sharareh Monemi, Lisa Crocker, Kevin Kalinsky, Shanu Modi, Kyung Hae Jung, Erika Hamilton, Patricia LoRusso, Ian Krop, Melissa M. Schutten, Renee Commerford, Mark X. Sliwkowski, Eunpi Cho
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Approved antibody-drug conjugates (ADCs) for HER2-positive breast cancer include trastuzumab emtansine and trastuzumab deruxtecan. To develop a differentiated HER2 ADC, we chose an antibody that does not compete with trastuzumab or pertuzuma
Externí odkaz:
https://doaj.org/article/654b41b090ea4a87be21fb42ec554dae
Autor:
Peter M Irving, Miles Parkes, Ruth Wood, Ailsa L Hart, Nicholas A Kennedy, Nick Powell, Julian R Marchesi, Tariq Ahmad, Tim Raine, Andrew King, James O Lindsay, Kevin Whelan, Charlie W Lees, Christopher A Lamb, Jack Satsangi, Emma Clark, Shriya Sharma, Xinyue Zhang, Christopher J Stewart, Naomi McGregor, Helen C Hancock, Rebecca H Maier, John C Mansfield, Mary Doona, Michelle Bardgett, Natalie J Prescott, Trevor Liddle, Robert Lees, Hannah Watson, Carl A Anderson, Ally Speight, Ciara Kennedy, Sarah Lawrence, Nicola J Wyatt, Jennifer A Doyle, Rebecca E McIntyre, Luke Jostins-Dean, Victoria Hildreth, James MS Wason, Dean Allerton, Dawn Clewes, Cristina Cotobal Martin, Katherine Frith, Sameena Iqbal, Laura Letchford, Jasmin Ostermayer, Tolulope Osunnuyi, Tara Shrestha, Michelle Strickland, Gregory R Young
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Characterised by chronic inflammation of the gastrointestinal tract, inflammatory bowel disease (IBD) symptoms including diarrhoea, abdominal pain and fatigue can significantly impact patient’s quality of life. Therapeutic developments
Externí odkaz:
https://doaj.org/article/12bb87e0caee4e31a4d86e9b0e5adbdd