Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Jack R. Nation"'
Autor:
Nigel Hart, Barry Setlow, Marci R. Mitchell, Paul J. Wellman, Jack R. Nation, Ian A. Mendez, Nicholas W. Simon
Publikováno v:
Behavioral Neuroscience. 124:470-477
Cocaine use is associated with high levels of impulsive choice (preference for immediate over delayed rewards), but it is not clear whether cocaine use causes elevated impulsive choice, or whether elevated impulsive choice is solely a predisposing fa
Publikováno v:
Journal of Psychopharmacology. 24:51-55
Behavioural studies have yielded results that show lobeline has the ability to attenuate d-methamphetamine self-administration. Further in vivo and in vitro studies have demonstrated a blockade of μ-opioid receptors with lobeline. The present invest
Autor:
P. Shane Clifford, Stephanie Barbee, Paul J. Wellman, Audrea E. Elliott, Chelsie N. Hollas, Jack R. Nation
Publikováno v:
Physiology & Behavior. 93:952-957
The alkaloid lobeline inhibits the function of vesicular monoamine and dopamine transporters and diminishes the behavioral and neurochemical effects of nicotine and amphetamines. In the present study, we examined the interaction of systemic administr
Publikováno v:
Life Sciences. 82:359-366
Female rats, relative to males, exhibit greater behavioral activation to cocaine and other psychostimulants, but the effect of sex and the estrous cycle in modulating the hypophagic action of cocaine has not been evaluated. Meal patterns were recorde
Publikováno v:
Pharmacology Biochemistry and Behavior. 88:89-93
Variations in dietary constituents such as carbohydrate are known to alter psychostimulant function in brain. Relatively few studies have examined the reinforcing effects of psychostimulants in subjects maintained on high-fat diets. The present exper
Publikováno v:
Experimental and Clinical Psychopharmacology. 14:245-253
Partial reinforcement is known to increase resistance to extinction (Rn) relative to training with continuous reinforcement. This phenomenon, referred to as the partial reinforcement extinction effect, is one of the most robust in learning and condit
Publikováno v:
Psychological Science in the Public Interest. 6:57-121
SUMMARY—Systematic research evaluating the separate and interacting impacts of neurotoxicants, micronutrients, and social environments on children's cognition and behavior has only recently been initiated. Years of extensive human epidemiologic and
Publikováno v:
Neuropsychopharmacology. 30:2058-2064
The rate of acquisition of drug self-administration may serve as a predictor of later drug-taking behavior, possibly influencing the vulnerability to use drugs. The present study examined the effects of perinatal (gestation/lactation) lead exposure o
Publikováno v:
Pharmacology Biochemistry and Behavior. 80:611-619
The present investigation examined the effects of perinatal lead exposure on cocaine self-administration following a GABAA antagonist pretreatment. Female rats were exposed to either 0 or 16 mg lead daily for 30 days prior to breeding with unexposed
Publikováno v:
NeuroToxicology. 25:869-875
This investigation examined the effects of perinatal cadmium exposure on subsequent self-administration of cocaine during the adult cycle. Female Sprague–Dawley rats were gavaged daily with 0.0 (14% sucrose solution, w/v) or 5.0 mg cadmium chloride