Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Jack R Bennink"'
Autor:
Courtney E Meilleur, Arash Memarnejadian, Adil N Shivji, Jenna M Benoit, Stephen W Tuffs, Tina S Mele, Bhagirath Singh, Jimmy D Dikeakos, David J Topham, Hong-Hua Mu, Jack R Bennink, John K McCormick, S M Mansour Haeryfar
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008393 (2020)
Infection with (SAg)-producing bacteria may precede or follow infection with or vaccination against influenza A viruses (IAVs). However, how SAgs alter the breadth of IAV-specific CD8+ T cell (TCD8) responses is unknown. Moreover, whether recall resp
Externí odkaz:
https://doaj.org/article/f610b5aac89a4fe5a0c71a022d8a9c93
Autor:
Stephanie S Cush, Glennys V Reynoso, Olena Kamenyeva, Jack R Bennink, Jonathan W Yewdell, Heather D Hickman
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005493 (2016)
Skin infection with the poxvirus vaccinia (VV) elicits a powerful, inflammatory cellular response that clears virus infection in a coordinated, spatially organized manner. Given the high concentration of pro-inflammatory effectors at areas of viral i
Externí odkaz:
https://doaj.org/article/c142891839534da5bbde6d2ae883f015
Lamprey VLRB response to influenza virus supports universal rules of immunogenicity and antigenicity
Publikováno v:
eLife, Vol 4 (2015)
Immunoglobulins (Igs) are a crown jewel of jawed vertebrate evolution. Through recombination and mutation of small numbers of genes, Igs can specifically recognize a vast variety of natural and man-made organic molecules. Jawless vertebrates evolved
Externí odkaz:
https://doaj.org/article/38c995b59f6e4f42b6a5fe63c1b0968f
Autor:
Javier G Magadán, Meghan O Altman, William L Ince, Heather D Hickman, James Stevens, Aaron Chevalier, David Baker, Patrick C Wilson, Rafi Ahmed, Jack R Bennink, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004204 (2014)
Antigenic variation in the globular domain of influenza A virus (IAV) hemagglutinin (HA) precludes effective immunity to this major human pathogen. Although the HA stem is highly conserved between influenza virus strains, HA stem-reactive antibodies
Externí odkaz:
https://doaj.org/article/74024ffa48a944a1a6108bc9315387d3
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33072 (2012)
Aminoacyl-tRNA synthetases (ARSs) are critical components of protein translation, providing ribosomes with aminoacyl-tRNAs. In return, ribosomes release uncharged tRNAs as ARS substrates. Here, we show that tRNA deacylation can be uncoupled from prot
Externí odkaz:
https://doaj.org/article/39f23fdb734e429e90f254385b527ba4
Autor:
Scott E Hensley, Suman R Das, James S Gibbs, Adam L Bailey, Loren M Schmidt, Jack R Bennink, Jonathan W Yewdell
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e15190 (2011)
Drugs inhibiting the influenza A virus (IAV) neuraminidase (NA) are the cornerstone of anti-IAV chemotherapy and prophylaxis in man. Drug-resistant mutations in NA arise frequently in human isolates, limiting the therapeutic application of NA inhibit
Externí odkaz:
https://doaj.org/article/a2918f031411439db2d136499f4de716
Autor:
Suman R Das, Pere Puigbò, Scott E Hensley, Darrell E Hurt, Jack R Bennink, Jonathan W Yewdell
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001211 (2010)
Antigenic drift in the influenza A virus hemagglutinin (HA) is responsible for seasonal reformulation of influenza vaccines. Here, we address an important and largely overlooked issue in antigenic drift: how does the number and location of glycosylat
Externí odkaz:
https://doaj.org/article/92959c454ab24da3bc03ba17da059bab
Autor:
Jack R. Bennink, Bernard A. P. Lafont
Publikováno v:
Viral Immunology
Autor:
Todd D. Schell, Christopher R. Shaler, S. M. Mansour Haeryfar, Arash Memarnejadian, Courtney E. Meilleur, Jack R. Bennink, Khashayarsha Khazaie
Publikováno v:
The Journal of Immunology. 199:3348-3359
The interactions between programmed death-1 (PD-1) and its ligands hamper tumor-specific CD8+ T cell (TCD8) responses, and PD-1-based “checkpoint inhibitors” have shown promise in certain cancers, thus revitalizing interest in immunotherapy. PD-1
Autor:
Pierre Faou, Jonathan W. Yewdell, Sara Oveissi, Mubing Duan, Ian G. Barr, Daniel Dlugolenski, John Stambas, Lenny Izzard, Jack R. Bennink, Damien Zanker, Nicole A. Mifsud, Benoît Van den Eynde, Siyuan Wan, David C. Tscharke, Xiaomu Zhang, Nathalie Vigneron, James S. Gibbs, Karen L. Laurie, Weisan Chen, Kun Xiao
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), Vol. 202, no.12, p. 3370-3380 (2019)
J Immunol
J Immunol
The importance of antiviral CD8+ T cell recognition of alternative reading frame (ARF)–derived peptides is uncertain. In this study, we describe an epitope (NS1-ARF21–8) present in a predicted 14-residue peptide encoded by the +1 register of NS1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00c7fe608addc95f93301d3bec74373
https://hdl.handle.net/2078.1/227231
https://hdl.handle.net/2078.1/227231