Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jack Monahan"'
Autor:
Adrien Leger, Ian Brettell, Jack Monahan, Carl Barton, Nadeshda Wolf, Natalja Kusminski, Cathrin Herder, Narendar Aadepu, Clara Becker, Jakob Gierten, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Tinatini Tavhelidse, Thomas Thumberger, Erika Tsingos, Philip Watson, Bettina Welz, Kiyoshi Naruse, Felix Loosli, Joachim Wittbrodt, Ewan Birney, Tomas Fitzgerald
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-24 (2022)
Abstract Background The teleost medaka (Oryzias latipes) is a well-established vertebrate model system, with a long history of genetic research, and multiple high-quality reference genomes available for several inbred strains. Medaka has a high toler
Externí odkaz:
https://doaj.org/article/6baa6b6529624872855129b4dacdee87
Autor:
Tomas Fitzgerald, Ian Brettell, Adrien Leger, Nadeshda Wolf, Natalja Kusminski, Jack Monahan, Carl Barton, Cathrin Herder, Narendar Aadepu, Jakob Gierten, Clara Becker, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Erika Tsingos, Tinatini Tavhelidse, Thomas Thumberger, Philip Watson, Bettina Welz, Nadia Khouja, Kiyoshi Naruse, Ewan Birney, Joachim Wittbrodt, Felix Loosli
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-32 (2022)
Abstract Background Unraveling the relationship between genetic variation and phenotypic traits remains a fundamental challenge in biology. Mapping variants underlying complex traits while controlling for confounding environmental factors is often pr
Externí odkaz:
https://doaj.org/article/63ed79c9a26844949500ec619ea7c20a
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006673 (2017)
Large-scale gene expression datasets are providing an increasing understanding of the location of cis-eQTLs in the human genome and their role in disease. However, little is currently known regarding the extent of regulatory site-sharing between gene
Externí odkaz:
https://doaj.org/article/4ef80935707e4eddaed761b6eae36318
Autor:
Jens Füllgrabe, Walraj S Gosal, Páidí Creed, Sidong Liu, Casper K Lumby, David J Morley, Tobias W B Ost, Albert J Vilella, Shirong Yu, Helen Bignell, Philippa Burns, Tom Charlesworth, Beiyuan Fu, Howerd Fordham, Nick Harding, Olga Gandelman, Paula Golder, Christopher Hodson, Mengjie Li, Marjana Lila, Yang Liu, Joanne Mason, Jason Mellad, Jack Monahan, Oliver Nentwich, Alexandra Palmer, Michael Steward, Minna Taipale, Audrey Vandomme, Rita Santo San-Bento, Ankita Singhal, Julia Vivian, Natalia Wójtowicz, Nathan Williams, Nicolas J Walker, Nicola C H Wong, Gary Yalloway, Joanna D Holbrook, Shankar Balasubaramanian
DNA comprises molecular information stored via genetic bases (G, C, T, A) and also epigenetic bases, principally 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC). Both genetic and epigenetic information are vital to our understanding of biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2af7acf13559572475f1c21b6cbf27
https://doi.org/10.1101/2022.07.08.499285
https://doi.org/10.1101/2022.07.08.499285
Autor:
Gavin D. Garland, Stephen P. Ducray, Leila Jahangiri, Perla Pucci, G. A. Amos Burke, Jack Monahan, Raymond Lai, Olaf Merkel, Ana-Iris Schiefer, Lukas Kenner, Andrew J. Bannister, Suzanne D. Turner
Publikováno v:
Cancers; Volume 14; Issue 1; Pages: 151
Cancers, Vol 14, Iss 151, p 151 (2022)
Cancers
Cancers, Vol 14, Iss 151, p 151 (2022)
Cancers
Simple Summary T-cell lymphoma is a cancer of the immune system. One specific sub-type of T-cell lymphoma is a malignancy called anaplastic large cell lymphoma (ALCL), which is distinct from the other forms, as in general, it has a better prognosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd815c4096169a0e2b74c229a852743
https://www.repository.cam.ac.uk/handle/1810/331950
https://www.repository.cam.ac.uk/handle/1810/331950
Autor:
Tomas Fitzgerald, Ian Brettell, Adrien Leger, Nadeshda Wolf, Natalja Kusminski, Jack Monahan, Carl Barton, Cathrin Herder, Narendar Aadepu, Jakob Gierten, Clara Becker, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Risa Suzuki, Erika Tsingos, Tinatini Tavhelidse, Thomas Thumberger, Philip Watson, Bettina Welz, Nadia Khouja, Kiyoshi Naruse, Ewan Birney, Joachim Wittbrodt, Felix Loosli
Unraveling the relationship between genetic variation and phenotypic traits remains a fundamental challenge in biology. Mapping variants underlying complex traits while controlling for confounding environmental factors is often problematic. To addres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12ca640d24ba59252e11ea0419fe3013
https://doi.org/10.1101/2021.05.17.444412
https://doi.org/10.1101/2021.05.17.444412
Autor:
Ivayla, Ivanova, Christian, Much, Monica, Di Giacomo, Chiara, Azzi, Marcos, Morgan, Pedro N, Moreira, Jack, Monahan, Claudia, Carrieri, Anton J, Enright, Dónal, O'Carroll
Publikováno v:
Molecular Cell
Summary YTHDF2 binds and destabilizes N6-methyladenosine (m6A)-modified mRNA. The extent to which this branch of m6A RNA-regulatory pathway functions in vivo and contributes to mammalian development remains unknown. Here we find that YTHDF2 deficienc
Autor:
Jack Monahan, Grace Hsieh, Deepa Kushwaha, David Kozono, Kaya Zhu, Kyle R. Cron, Alan D. D'Andrea, Clark C. Chen, Dmitry Merzon
Publikováno v:
Cancer Research. 73:1583-1583
Background: Each year, ∼60,000 US patients are diagnosed with locally advanced non-small cell lung carcinoma (NSCLC). Despite optimal radiation therapy (RT), chemotherapy +/- surgery, over 30% of patients fails locoregionally. The addition of concu
Autor:
Tomas, Fitzgerald, Ian, Brettell, Adrien, Leger, Nadeshda, Wolf, Natalja, Kusminski, Jack, Monahan, Carl, Barton, Cathrin, Herder, Narendar, Aadepu, Jakob, Gierten, Clara, Becker, Omar T, Hammouda, Eva, Hasel, Colin, Lischik, Katharina, Lust, Natalia, Sokolova, Risa, Suzuki, Erika, Tsingos, Tinatini, Tavhelidse, Thomas, Thumberger, Philip, Watson, Bettina, Welz, Nadia, Khouja, Kiyoshi, Naruse, Ewan, Birney, Joachim, Wittbrodt, Felix, Loosli
Publikováno v:
Genome biology, 23 (1), Article no: 59
Unraveling the relationship between genetic variation and phenotypic traits remains a fundamental challenge in biology. Mapping variants underlying complex traits while controlling for confounding environmental factors is often problematic. To addres