Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jack Mellor"'
Autor:
Jithin D. Nair, Kevin A. Wilkinson, Busra P. Yucel, Christophe Mulle, Bryce Vissel, Jack Mellor, Jeremy M. Henley
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107708- (2023)
Summary: Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored. Here, we compared GluK2 editing-deficient mice that express ∼95% une
Externí odkaz:
https://doaj.org/article/2e9a29431f0b4c69a47eaa9ed3c10a74
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 2 (2010)
Associative synaptic plasticity is synapse specific and requires coincident activity in presynaptic and postsynaptic neurons to activate NMDA receptors (NMDARs). The resultant Ca2+ influx is the critical trigger for the induction of synaptic plastici
Externí odkaz:
https://doaj.org/article/3f564ff2891b41c2893a19fa5eb75ff5
Autor:
Katherine Buchanan, Jack Mellor
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 2 (2010)
Synaptic plasticity has historically been investigated most intensely in the hippocampus and therefore it is somewhat surprising that the majority of studies on spike timing-dependent plasticity (STDP) have focused not in the hippocampus but on synap
Externí odkaz:
https://doaj.org/article/e2805ebeb37142919531f505dea782e8
Autor:
Hannah Klim, Timothy William, Jack Mellors, Caolann Brady, Giri S. Rajahram, Tock H. Chua, Helena Brazal Monzó, Jecelyn Leslie John, Kelly da Costa, Mohammad Saffree Jeffree, Nigel J. Temperton, Tom Tipton, Craig P. Thompson, Kamruddin Ahmed, Chris J. Drakeley, Miles W. Carroll, Kimberly M. Fornace
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cases of H5 highly pathogenic avian influenzas (HPAI) are on the rise. Although mammalian spillover events are rare, H5N1 viruses have an estimated mortality rate in humans of 60%. No human cases of H5 infection have been reported in Malaysi
Externí odkaz:
https://doaj.org/article/bd933e2d3cc94517949f10657ffb0d2d
Publikováno v:
Annals of Work Exposures and Health. 67:i22-i22
Sampling of diesel fume particulates onto filters from workplace atmospheres with subsequent analysis for an elemental carbon marker using a laboratory-based combustion technique is well established with procedures codified in both European and Ameri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb12ccef04b8a0b496777946efe6bc70
https://doi.org/10.1093/annweh/wxac087.059
https://doi.org/10.1093/annweh/wxac087.059
Publikováno v:
Annals of Work Exposures and Health. 67:i23-i23
Silicosis, one of the oldest recorded occupational diseases, is a form of lung disease caused by the inhalation of respirable crystalline silica (RCS) within occupational settings such as quarrying, foundries, potteries and stone masonry. Hence worke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::181faef683d0214d992377121d9e235f
https://doi.org/10.1093/annweh/wxac087.061
https://doi.org/10.1093/annweh/wxac087.061
Publikováno v:
Proceedings of the 32nd International Symposium on Ballistics.
The performance of a shaped charge warhead is a direct consequence of specific design features such as the liner geometry. By dynamically modifying the geometry of the shaped charge design through a newly developed hydrocode optimisation and paramete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146a3855aa49a3f685475a89f18a5929
https://doi.org/10.12783/ballistics22/36076
https://doi.org/10.12783/ballistics22/36076
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 8 (2016)
ResearcherID
ResearcherID
The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories. The creation of these CA3 ensembles depends on neuromodulatory input
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::691a5c328ad9562cf566995456791b09
http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00032/full
http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00032/full
Autor:
Adriana Tomic, Donal T. Skelly, Ane Ogbe, Daniel O’Connor, Matthew Pace, Emily Adland, Frances Alexander, Mohammad Ali, Kirk Allott, M. Azim Ansari, Sandra Belij-Rammerstorfer, Sagida Bibi, Luke Blackwell, Anthony Brown, Helen Brown, Breeze Cavell, Elizabeth A. Clutterbuck, Thushan de Silva, David Eyre, Sheila Lumley, Amy Flaxman, James Grist, Carl-Philipp Hackstein, Rachel Halkerston, Adam C. Harding, Jennifer Hill, Tim James, Cecilia Jay, Síle A. Johnson, Barbara Kronsteiner, Yolanda Lie, Aline Linder, Stephanie Longet, Spyridoula Marinou, Philippa C. Matthews, Jack Mellors, Christos Petropoulos, Patpong Rongkard, Cynthia Sedik, Laura Silva-Reyes, Holly Smith, Lisa Stockdale, Stephen Taylor, Stephen Thomas, Timothy Tipoe, Lance Turtle, Vinicius Adriano Vieira, Terri Wrin, OPTIC Clinical Group, PITCH Study Group, C-MORE Group, Andrew J. Pollard, Teresa Lambe, Chris P. Conlon, Katie Jeffery, Simon Travis, Philip Goulder, John Frater, Alex J. Mentzer, Lizzie Stafford, Miles W. Carroll, William S. James, Paul Klenerman, Eleanor Barnes, Christina Dold, Susanna J. Dunachie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The engagement of immunological memory is a key component to the protective anti-SARS-CoV-2 B and T cell responses. Here the authors assess the B and T cells of a cohort of UK healthcare workers in response to infection and longitudinally track the c
Externí odkaz:
https://doaj.org/article/2417a49e71464bef98f394f4f14f9e6e
Autor:
Jack Mellors, Tom Tipton, Sarah Katharina Fehling, Joseph Akoi Bore, Fara Raymond Koundouno, Yper Hall, Jacob Hudson, Frances Alexander, Stephanie Longet, Stephen Taylor, Andrew Gorringe, N’Faly Magassouba, Mandy Kader Konde, Julian Hiscox, Thomas Strecker, Miles Carroll
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The 2013–2016 Ebola virus (EBOV) epidemic in West Africa was unprecedented in case numbers and fatalities, and sporadic outbreaks continue to arise. Antibodies to the EBOV glycoprotein (GP) are strongly associated with survival and their use in imm
Externí odkaz:
https://doaj.org/article/c794e7601b4547d6ac2a0d3c23b54e9c