Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jack MF Su"'
Autor:
Zi-Lu Huang, Zhi-Gang Liu, Qi Lin, Ya-Lan Tao, Xinzhuoyun Li, Patricia Baxter, Jack MF Su, Adekunle M. Adesina, Chris Man, Murali Chintagumpala, Wan Yee Teo, Yu-Chen Du, Yun-Fei Xia, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101988- (2024)
Radiation is one of the standard therapies for pediatric high-grade glioma (pHGG), of which the prognosis remains poor. To gain an in-depth understanding of biological consequences beyond the classic DNA damage, we treated 9 patient-derived orthotopi
Externí odkaz:
https://doaj.org/article/42c4611929cf4552aa6cf7dffa17679b
Autor:
Wan-Yee Teo, Shiying Huang, Sekar Karthik, Qi Lin, YuChen Du, Ching C Lau, Adesina Adekunle, Jack MF Su, Angela Major, M. Tarek Elghetany, Kam-Man Hui, Xiaonan Li
Publikováno v:
WFNOS 2022 Abstract Book.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c443e32bea3213a8ed48080aedf6a924
https://doi.org/10.14791/btrt.2022.10.f-2685
https://doi.org/10.14791/btrt.2022.10.f-2685
Autor:
Sibo Zhao, Huiyuan Zhang, Jack Mf Su, Xiao-Nan Li, Lei Guo, Mari Kogiso, Lin Qi, Malcolm A. Smith, Frank K. Braun, Stephen W. Erickson, Patricia Baxter, Eric J. Earley, Yuchen Du, Beverly A. Teicher, Sophie Xiao, Holly Lindsay, Sarah Injac
Publikováno v:
Lab Invest
Brain tumors are the leading cause of cancer-related death in children. Tazemetostat is an FDA-approved enhancer of zeste homolog (EZH2) inhibitor. To determine its role in difficult-to-treat pediatric brain tumors, we examined EZH2 levels in a panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d225cd17e3396922703c2c8ea4b6e858
https://pubmed.ncbi.nlm.nih.gov/34802040
https://pubmed.ncbi.nlm.nih.gov/34802040
Autor:
Laszlo Perlaky, Zhigang Liu, Adekunle M. Adesina, Jianhua Yang, Holly Lindsay, Jack Mf Su, Xiumei Zhao, Huiyuan Zhang, Murali Chintagumpala, Mari Kogiso, Wan-Yee Teo, Xiao-Nan Li, Yuchen Du, Ching C. Lau, Patricia Baxter, Xingding Zhang, Sibo Zhao, Frank K. Braun, Litian Yu, Yulun Huang, Chris Man, Lin Qi
Publikováno v:
Cancer Lett
Brain tumor is the leading cause of cancer related death in children. Clinically relevant animals are critical for new therapy development. To address the potential impact of animal gender on tumorigenicity rate, xenograft growth and in vivo drug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a80fdb303acdc6007856c0a72423e8
https://europepmc.org/articles/PMC10306089/
https://europepmc.org/articles/PMC10306089/
Autor:
Holly Lindsay, Sarah Injac, Stacey L. Berg, Frank K. Braun, Mark G. Qian, Huiyuan Zhang, Xiao-Nan Li, Yuchen Du, Patricia Baxter, Adekunle M. Adesina, Sibo Zhao, Mari Kogiso, Debra Liao, Frank Y. Lin, Jodi A. Muscal, Jack Mf Su, Linna Zhang, Lin Qi
Publikováno v:
Clinical Cancer Research. 24:2159-2170
Purpose: Pediatric glioblastoma multiforme (pGBM) is a highly aggressive tumor in need of novel therapies. Our objective was to demonstrate the therapeutic efficacy of MLN8237 (alisertib), an orally available selective inhibitor of Aurora A kinase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c3aa5fb278e2d8d6b6197b2c65529a
https://doi.org/10.1158/1078-0432.ccr-17-2256
https://doi.org/10.1158/1078-0432.ccr-17-2256
Autor:
Xiao-Nan Li, Wan-Yee Teo, M. Tarek Elghetany, Aixin Yap, Jack Mf Su, Kam M. Hui, Angela Major
Publikováno v:
Neuro-Oncology. 19:iv38-iv39
Medulloblastoma (MB) is the most common childhood malignant brain tumor. We have previously described the presence of tumor-infiltrating macrophages among patient MBs (n=60). There are diverse subsets of tumor-infiltrating macrophages, we studied one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab5d013f09a9183588273b3949aa49f
https://doi.org/10.1093/neuonc/nox083.158
https://doi.org/10.1093/neuonc/nox083.158
Autor:
Lindsay Holly, Adekunle M. Adesina, Kogiso Mari, Will Parsons, Xiumei Zhao, Lin Qi, Liu Zhigang, Du Yuchen, Andrew W. Walter, Baxter A. Patricia, Jeffery Murray, Javad Nazarian, Murali Chintagumpala, Susan M. Blaney, Jack Mf Su, Yujing Zhang, Xiao-Nan Li, Rene Y. McNall-Knapp
Publikováno v:
Cancer Research. 75:1450-1450
Brain tumors are the leading cause of cancer related death in children, and there is biological differences between treatment naïve tumors and their therapy resistant relapses. As surgery is rarely an option for terminal brain tumors that have faile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31f0390a4b204ee3b23c76bbacd37b66
https://doi.org/10.1158/1538-7445.am2015-1450
https://doi.org/10.1158/1538-7445.am2015-1450
Autor:
Xiao-Nan Li, Jack Mf Su, Jeffrey C. Murray, Donald W. Parsons, Adekunle M. Adesina, Patricia Baxter, Mari Kogiso, Laszlo Perlaky, Holly Lindsay, Lin Qi, Murali Chintagumpala
Publikováno v:
Cancer Research. 75:3292-3292
Introduction: Atypical teratoid rhabdoid tumors (ATRTs) are a high grade pediatric brain malignancy with extremely poor survival outcomes. They are molecularly defined by deletions or mutations in the tumor suppressor gene INI1. INI1 deficiency cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e9c10642f817fad52827e2e205be96a
https://doi.org/10.1158/1538-7445.am2015-3292
https://doi.org/10.1158/1538-7445.am2015-3292
Autor:
Yulun Huang, Murali Chintagumpala, Laszlo Perlaky, Mari Kogiso, Hua Mao, Patricia Baxter, Ching C. Lau, Lin Qi, Jack Mf Su, Xiao-Nan Li
Publikováno v:
Cancer Research. 74:1484-1484
Glioblastoma multiforme (GBM) is the most aggressive and lethal brain tumor that occurs both in children and adults. Diffuse invasion into normal brain tissue is one of the important biologic features that make GBM refractory to conventional therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::055e46bded0b29e2b1ea7de379f3a7df
https://doi.org/10.1158/1538-7445.am2014-1484
https://doi.org/10.1158/1538-7445.am2014-1484