Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jack M. Gallup"'
Autor:
Dirk Roymans, Sarhad S Alnajjar, Michael B Battles, Panchan Sitthicharoenchai, Polina Furmanova-Hollenstein, Peter Rigaux, Joke Van den Berg, Leen Kwanten, Marcia Van Ginderen, Nick Verheyen, Luc Vranckx, Steffen Jaensch, Eric Arnoult, Richard Voorzaat, Jack M. Gallup, Alejandro Larios-Mora, Marjolein Crabbe, Dymphy Huntjens, Pierre Raboisson, Johannes P. Langedijk, Mark R. Ackermann, Jason S McLellan, Sandrine Vendeville, Anil Koul
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Respiratory syncytial virus causes lung infections in children, immunocompromised adults, and in the elderly. Here the authors show that a chemical inhibitor to a viral fusion protein is effective in reducing viral titre and ameliorating infection in
Externí odkaz:
https://doaj.org/article/a53af0caadf64c108081ce0c70f541ee
Autor:
Rachel J. Derscheid, Albert van Geelen, Jodi L. McGill, Jack M. Gallup, Tomas Cihlar, Randy E. Sacco, Mark R. Ackermann
Publikováno v:
Viruses, Vol 5, Iss 11, Pp 2881-2897 (2013)
Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in infants and young children. A small percentage of these individuals develop severe and even fatal disease. To better understand the pathogenesis of severe disease and deve
Externí odkaz:
https://doaj.org/article/f3bb42783f9a44429af4d550a43ac393
Autor:
Albert Van Geelen, Mark R. Ackermann, Laurent Detalle, Thomas Stohr, Linde Duprez, Alejandro Larios Mora, Jack M. Gallup
Publikováno v:
mAbs. 10:778-795
Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory disease in infants and young children worldwide. Currently, treatment is supportive and no vaccines are available. The use of newborn lambs to model hRSV infection in huma
Autor:
Laurent Detalle, Thomas Stohr, Sarhad Alnajjar, Albert Van Geelen, Linde Duprez, Panchan Sitthicharoenchai, Alejandro Lorios‐Mora, Anne Brochot, Mark R. Ackermann, Jack M Gallup
Publikováno v:
The FASEB Journal. 33
Autor:
Mark R. Ackermann, David Verhoeven, Jack M. Gallup, Panchan Sitthicharoenchai, Sarhad Alnajjar
Publikováno v:
The FASEB Journal. 32
Human Respiratory Syncytial Virus Memphis 37 Causes Acute Respiratory Disease in Perinatal Lamb Lung
Autor:
Albert Van Geelen, Tomas A. Cihlar, Daniel A. Shelly, Rachel J. Derscheid, Jack M. Gallup, Thomas Kienzle, Robert R. King, Mark R. Ackermann
Publikováno v:
BioResearch Open Access, Vol 3, Iss 2, Pp 60-69 (2014)
BioResearch Open Access
BioResearch Open Access
Respiratory syncytial virus (RSV) is the leading cause of hospitalization due to respiratory illness among infants and young children of industrialized countries. There is a lack of understanding of the severe disease mechanisms as well as limited tr
Autor:
Sarhad Alnajjar, Alejandro Larios-Mora, Marjolein Crabbe, Dymphy Huntjens, Eric Arnoult, Nick Verheyen, Jason S. McLellan, Mark R. Ackermann, Jack M. Gallup, Anil Koul, Leen Kwanten, Michael B. Battles, Steffen Jaensch, Joke Van den Berg, Luc Vranckx, Marcia Van Ginderen, Dirk Roymans, Panchan Sitthicharoenchai, Richard Voorzaat, Peter Rigaux, Sandrine Vendeville, Pierre Jean-Marie Bernard Raboisson, Polina Furmanova-Hollenstein, Johannes P. M. Langedijk
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Respiratory syncytial virus is a major cause of acute lower respiratory tract infection in young children, immunocompromised adults, and the elderly. Intervention with small-molecule antivirals specific for respiratory syncytial virus presents an imp
Autor:
Christopher K. Tuggle, Meghan J. Wymore, Mark R. Ackermann, Dan Nettleton, Cumhur Yusuf Demirkale, Amanda E. Ramer-Tait, Jack M. Gallup, Albert E. Jergens, Vicki L. Wilke, Michael J. Wannemuehler
Publikováno v:
American Journal of Veterinary Research. 73:1219-1229
Objective—To characterize mucosal gene expression in dogs with chronic enteropathy (CE). Animals—18 dogs with CE and 6 healthy control dogs. Procedures—Small intestinal mucosal biopsy specimens were endoscopically obtained from dogs. Disease se
Autor:
Jack M. Gallup, Mark R. Ackermann, Rachel J. Derscheid, Subramaniam Krishnan, Fatoumata B. Sow
Publikováno v:
Immunological Investigations. 41:304-316
Perinatal lambs are increasingly appreciated as a model to study respiratory infections of premature and newborn human infants. To explore the relationship between developmental age and immunological competence in the respiratory tract, the basal lev
Autor:
Alicia K. Olivier, Jack M. Gallup, Mark R. Ackermann, Marcia M.M.A. de Macedo, Steven M. Varga
Publikováno v:
International Journal of Experimental Pathology. 90:431-438
Human respiratory syncytial virus (hRSV) is a pneumovirus that causes significant respiratory disease in premature and full-term infants. It was our hypothesis that a common strain of RSV, strain A2, would infect, cause pulmonary pathology, and alter