Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Jack M. F. Su"'
1
Akademický článek
Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas
Autor: Sibo Zhao, Jia Li, Huiyuan Zhang, Lin Qi, Yuchen Du, Mari Kogiso, Frank K. Braun, Sophie Xiao, Yulun Huang, Jianfang Li, Wan-Yee Teo, Holly Lindsay, Patricia Baxter, Jack M. F. Su, Adekunle Adesina, Miklós Laczik, Paola Genevini, Anne-Clemence Veillard, Sol Schvartzman, Geoffrey Berguet, Shi-Rong Ding, Liping Du, Clifford Stephan, Jianhua Yang, Peter J. A. Davies, Xinyan Lu, Murali Chintagumpala, Donald William Parsons, Laszlo Perlaky, Yun-Fei Xia, Tsz-Kwong Man, Yun Huang, Deqiang Sun, Xiao-Nan Li
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
While recurrence is frequent in ependymoma, the underlying molecular mechanisms remain to be explored. Here, the authors investigate epigenetic, genetic and tumorigenic changes in 30 patient-matched repeated relapses over 13 years and identify distin
Externí odkaz: https://doaj.org/article/67ce4ebc1c4e4e89b80aca05d5ec1d5f
Zobrazit plný text záznamu
2
Akademický článek
Maximizing the potential of aggressive mouse tumor models in preclinical drug testing
Autor: M. Tarek Elghetany, Jia-Min Ho, Lois Hew Shi-Qi, Sekar Karthik, Jack M. F. Su, Qi Lin, YuChen Du, Jianhe Shen, Wing-Yuk Chow, Ching C. Lau, Adekunle Adesina, Angela Major, Anat Erdreich-Epstein, Kam-Man Hui, Xiao-Nan Li, Wan-Yee Teo
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Atypical teratoid rhabdoid tumor (ATRT) is an aggressive embryonal brain tumor among infants and young children. Two challenges exist for preclinical testing in ATRT. First, genetically quiet, ATRT is a difficult tumor to target molecularly.
Externí odkaz: https://doaj.org/article/de5f4ee8efbe4626bc463e33bc5fd9a4
Zobrazit plný text záznamu
3
Akademický článek
Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion
Autor: Yulun Huang, Lin Qi, Mari Kogiso, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Sophie Xiao, Wan‐Yee Teo, Holly Lindsay, Sibo Zhao, Patricia Baxter, Jack M. F. Su, Adekunle Adesina, Jianhua Yang, Sebastian Brabetz, Marcel Kool, Stefan M. Pfister, Murali Chintagumpala, Laszlo Perlaky, Zhong Wang, Youxin Zhou, Tsz‐Kwong Man, Xiao‐Nan Li
Publikováno v: Advanced Science, Vol 8, Iss 23, Pp n/a-n/a (2021)
Abstract Diffuse invasion is the primary cause of treatment failure of glioblastoma (GBM). Previous studies on GBM invasion have long been forced to use the resected tumor mass cells. Here, a strategy to reliably isolate matching pairs of invasive (G
Externí odkaz: https://doaj.org/article/d951663ff7d440bebd6494e2644f1aa3
Zobrazit plný text záznamu
5
MEDB-08. Inhibition of different mitotic targets demonstrated distinct DNA damage and cell death response in p53-mutant medulloblastoma
Autor: Shiying Huang, Jie-Ling Pan, Sekar Karthik, YuChen Du, Qi Lin, Ching C Lau, Adesina Adekunle, Jack M F Su, Angela Major, M Tarek Elghetany, Kam-Man Hui, Xiaonan Li, Wan-Yee Teo
Publikováno v: Neuro-Oncology. 24:i105-i105
BACKGROUND: In normal cells, cell cycle is tightly regulated by mitotic proteins to ensure smooth transition through each phase of cell division. Here, we examine two proteins – KIF11, a mitotic kinesin, responsible for assembly and maintenance of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ad6d8c100ec7e764fb9101af68cf46d
https://doi.org/10.1093/neuonc/noac079.383
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje