Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jack M Monahan"'
Autor:
Ian J Groves, Emma L A Drane, Marco Michalski, Jack M Monahan, Cinzia G Scarpini, Stephen P Smith, Giovanni Bussotti, Csilla Várnai, Stefan Schoenfelder, Peter Fraser, Anton J Enright, Nicholas Coleman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009875 (2021)
Development of cervical cancer is directly associated with integration of human papillomavirus (HPV) genomes into host chromosomes and subsequent modulation of HPV oncogene expression, which correlates with multi-layered epigenetic changes at the int
Externí odkaz:
https://doaj.org/article/c2ebaa15d87542a8b9191e3a5a74e587
Autor:
Jens Füllgrabe, Walraj S. Gosal, Páidí Creed, Sidong Liu, Casper K. Lumby, David J. Morley, Tobias W. B. Ost, Albert J. Vilella, Shirong Yu, Helen Bignell, Philippa Burns, Tom Charlesworth, Beiyuan Fu, Howerd Fordham, Nicolas J. Harding, Olga Gandelman, Paula Golder, Christopher Hodson, Mengjie Li, Marjana Lila, Yang Liu, Joanne Mason, Jason Mellad, Jack M. Monahan, Oliver Nentwich, Alexandra Palmer, Michael Steward, Minna Taipale, Audrey Vandomme, Rita Santo San-Bento, Ankita Singhal, Julia Vivian, Natalia Wójtowicz, Nathan Williams, Nicolas J. Walker, Nicola C. H. Wong, Gary N. Yalloway, Joanna D. Holbrook, Shankar Balasubramanian
Publikováno v:
Nature Biotechnology.
DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology. Most DNA sequencing approaches address either genetics or epigenetics and thus capture incomplete information. Method
Autor:
Watson P, Suzuki R, Adrien Leger, Brettell I, Felix Loosli, Thomas Thumberger, Erika Tsingos, Katharina Lust, Narendar Aadepu, Wolf N, Cathrin Herder, Jakob Gierten, Tinatini Tavhelidse, Kusminski N, Clara Becker, Omar T. Hammouda, Carl Barton, Jochen Wittbrodt, Colin Q. Lischik, Kiyoshi Naruse, Eva Hasel, Jack M. Monahan, Ewan Birney, Tomas W Fitzgerald, Bettina Welz
Publikováno v:
Genome biology, 23 (1), Article no: 58
Genome Biology
Genome Biology
Background The teleost medaka (Oryzias latipes) is a well-established vertebrate model system, with a long history of genetic research, and multiple high-quality reference genomes available for several inbred strains. Medaka has a high tolerance to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2daecd8a1547ce141309cbab1c1797e
https://eprints.bbk.ac.uk/id/eprint/44359/8/44359a.pdf
https://eprints.bbk.ac.uk/id/eprint/44359/8/44359a.pdf
Autor:
Stephen Smith, Giovanni Bussotti, Cinzia G. Scarpini, Nicholas Coleman, Peter Fraser, Stefan Schoenfelder, Jack M. Monahan, Anton J. Enright, Ian J. Groves, Csilla Várnai, Emma L. A. Drane, Marco Michalski
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 8, p e1009875 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009875 (2021)
Development of cervical cancer is directly associated with integration of human papillomavirus (HPV) genomes into host chromosomes and subsequent modulation of HPV oncogene expression, which correlates with multi-layered epigenetic changes at the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54580ade474293234e2a2d3bbb1fa7ba
https://www.repository.cam.ac.uk/handle/1810/328538
https://www.repository.cam.ac.uk/handle/1810/328538
Autor:
Emma L. A. Drane, Nicholas Coleman, Cinzia G. Scarpini, Marco Michalski, Csilla Várnai, Giovanni Bussotti, Stephen Smith, Anton J. Enright, Jack M. Monahan, Stefan Schoenfelder, Ian J. Groves, Peter Fraser
Development of cervical cancer is directly associated with integration of human papillomavirus (HPV) genomes into host chromosomes and subsequent modulation of HPV oncogene expression, which correlates with multi-layered epigenetic changes at the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fe99a0be6953128acbf002c0f423d5
https://hal-pasteur.archives-ouvertes.fr/pasteur-03210819/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03210819/document
Autor:
Ivayla Ivanova, Stefano Comazzetto, Bo T. Porse, Christian Much, Robin C. Allshire, Lina Vasiliauskaitė, Tatsiana Auchynnikava, Juri Rappsilber, Dimitrios Vitsios, Anton J. Enright, Jack M. Monahan, Marcos Morgan, Monica Di Giacomo, Dónal O'Carroll, Yuka Kabayama
Publikováno v:
Morgan, M, Kabayama, Y, Much, C, Ivanova, I, Di Giacomo, M, Auchynnikava, T, Monahan, J M, Vitsios, D M, Vasiliauskaite, L, Comazzetto, S, Rappsilber, J, Allshire, R C, Porse, B T, Enright, A J & O'Carroll, D 2019, ' A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis ', Cell Research, vol. 29, pp. 221-232 . https://doi.org/10.1038/s41422-018-0128-1
Cell Research
Morgan, M, Kabayama, Y, Much, C, Ivanova, I, Di Giacomo, M, Auchynnikava, T, Monahan, J M, Vitsios, D M, Vasiliauskaitė, L, Comazzetto, S, Rappsilber, J, Allshire, R C, Porse, B T, Enright, A J & O'Carroll, D 2019, ' A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis ', Cell Research, pp. 221–232 . https://doi.org/10.1038/s41422-018-0128-1
Cell Research
Morgan, M, Kabayama, Y, Much, C, Ivanova, I, Di Giacomo, M, Auchynnikava, T, Monahan, J M, Vitsios, D M, Vasiliauskaitė, L, Comazzetto, S, Rappsilber, J, Allshire, R C, Porse, B T, Enright, A J & O'Carroll, D 2019, ' A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis ', Cell Research, pp. 221–232 . https://doi.org/10.1038/s41422-018-0128-1
Several developmental stages of spermatogenesis are transcriptionally quiescent which presents major challenges associated with the regulation of gene expression. Here we identify that the zygotene to pachytene transition is not only associated with
Autor:
Geeta G. Sharma, Sorcha Forde, Hélène Pacquement, Ivonne A. Montes-Mojarro, Ralf Jauch, Wolfram Klapper, Cosimo Lobello, Liam C. Lee, Luca Mologni, Anne Lambilliotte, Suzanne D. Turner, Laurence Brugières, Roberto Chiarle, Stephen P. Ducray, Jamie D. Matthews, Birgit Geoerger, Shahid Pervez, Carlo Gambacorti-Passerini, Lukas Kenner, Šárka Pospíšilová, Klaas Bahnsen, Shi-Lu Luan, Nina Prokoph, Andrea Janíková, G. A. Amos Burke, Olaf Merkel, Huan-Chang Liang, Elif Karaca-Atabay, Hugo Larose, Wilhelm Woessmann, Qi Wang, Andishe Attarbaschi, Jack M. Monahan, Vikas Malik, Judith Landman-Parker, Isaia Barbieri, Gilles Vassal, Gudrun Schleiermacher, Nicola A. Probst
Anaplastic large cell lymphoma (ALCL) is a T-cell malignancy predominantly driven by a hyperactive anaplastic lymphoma kinase (ALK) fusion protein. ALK inhibitors, such as crizotinib, provide alternatives to standard chemotherapy with reduced toxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae853e045a135b7e317c7f6be0735d41
https://www.repository.cam.ac.uk/handle/1810/305799
https://www.repository.cam.ac.uk/handle/1810/305799
Autor:
Matthew P. Davis, Alena Shkumatava, Tania Auchynnikava, Giovanni Bussotti, Harpreet K Saini, Juri Rappsilber, Jack M. Monahan, Claudia Carrieri, Anton J. Enright, Stijn van Dongen, Angelo Bitetti, Tommaso Leonardi, Robin C. Allshire, Dónal O'Carroll
Publikováno v:
Davis, M P, Carrieri, C, Saini, H K, van Dongen, S, Leonardi, T, Bussotti, G, Monahan, J M, Auchynnikava, T, Bitetti, A, Rappsilber, J, Allshire, R C, Shkumatava, A, O'Carroll, D & Enright, A J 2017, ' Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution ', EMBO Reports . https://doi.org/10.15252/embr.201744059
EMBO Reports
EMBO Reports
Spermatogenesis is associated with major and unique changes to chromosomes and chromatin. Here, we sought to understand the impact of these changes on spermatogenic transcriptomes. We show that long terminal repeats (LTRs) of specific mouse endogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b781a2e13b8c255567ada534c120653
https://www.repository.cam.ac.uk/handle/1810/269628
https://www.repository.cam.ac.uk/handle/1810/269628
Autor:
Vydianathan Ravi, Shipra Bhatia, Sydney Brenner, Byrappa Venkatesh, Dirk A. Kleinjan, Philippe Gautier, Emma Murdoch, Jack M. Monahan, Veronica van Heyningen
Publikováno v:
Developmental Biology. 387:214-228
Biological differences between cell types and developmental processes are characterised by differences in gene expression profiles. Gene-distal enhancers are key components of the regulatory networks that specify the tissue-specific expression patter
Autor:
Füllgrabe, Jens, Gosal, Walraj S., Creed, Páidí, Liu, Sidong, Lumby, Casper K., Morley, David J., Ost, Tobias W. B., Vilella, Albert J., Yu, Shirong, Bignell, Helen, Burns, Philippa, Charlesworth, Tom, Fu, Beiyuan, Fordham, Howerd, Harding, Nicolas J., Gandelman, Olga, Golder, Paula, Hodson, Christopher, Li, Mengjie, Lila, Marjana
Publikováno v:
Nature Biotechnology; Oct2023, Vol. 41 Issue 10, p1457-1464, 8p