Zobrazeno 1 - 10
of 24 080
pro vyhledávání: '"Jack M"'
Autor:
Sudarshawn Damodharan, Jack M. Shireman, Elliot Xie, Emily Distler, Christina Kendziorski, Mahua Dey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Diffuse midline glioma, H3 K27-altered (DMG) are highly aggressive malignancies of the central nervous system (CNS) that primarily affect the pediatric population. Large scale spatial transcriptomic studies have implicated that tumor microen
Externí odkaz:
https://doaj.org/article/c66719fe1c1c47af9c7b1eaff611319a
Autor:
Arthur S. Lee, Lauren J. Ayers, Michael Kosicki, Wai-Man Chan, Lydia N. Fozo, Brandon M. Pratt, Thomas E. Collins, Boxun Zhao, Matthew F. Rose, Alba Sanchis-Juan, Jack M. Fu, Isaac Wong, Xuefang Zhao, Alan P. Tenney, Cassia Lee, Kristen M. Laricchia, Brenda J. Barry, Victoria R. Bradford, Julie A. Jurgens, Eleina M. England, Monkol Lek, Daniel G. MacArthur, Eunjung Alice Lee, Michael E. Talkowski, Harrison Brand, Len A. Pennacchio, Elizabeth C. Engle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Unsolved Mendelian cases often lack obvious pathogenic coding variants, suggesting potential non-coding etiologies. Here, we present a single cell multi-omic framework integrating embryonic mouse chromatin accessibility, histone modification
Externí odkaz:
https://doaj.org/article/1d31f2afe5204250bcedb785593a825f
Autor:
Zhichao Wu, Karen Dazelle, Zied Abdullaev, Hye-Jung Chung, Sonika Dahiya, Matthew Wood, Han Lee, Calixto-Hope G. Lucas, Qinwen Mao, Lorraina Robinson, Igor Fernandes, Matthew McCord, Peter Pytel, Kyle S. Conway, Rebecca Yoda, Jennifer M. Eschbacher, Ossama M. Maher, Martin Hasselblatt, Bret C. Mobley, Jack M. Raisanen, Kimmo J. Hatanpaa, Joshua Byers, Norman L. Lehman, Patrick J. Cimino, Drew Pratt, Martha Quezado, Kenneth Aldape
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-7 (2024)
Abstract Papillary tumor of the pineal region (PTPR) is an uncommon tumor of the pineal region with distinctive histopathologic and molecular characteristics. Experience is limited with respect to its molecular heterogeneity and clinical characterist
Externí odkaz:
https://doaj.org/article/ccb5b973f4b744df99cf76d1b717245c
Autor:
Jessica Knox, Andrew R. Burns, Brittany Cooke, Savina R. Cammalleri, Megan Kitner, Justin Ching, Jack M. P. Castelli, Emily Puumala, Jamie Snider, Emily Koury, J. B. Collins, Salma Geissah, James J. Dowling, Erik C. Andersen, Igor Stagljar, Leah E. Cowen, Mark Lautens, Inga Zasada, Peter J. Roy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Left unchecked, plant-parasitic nematodes have the potential to devastate crops globally. Highly effective but non-selective nematicides are justifiably being phased-out, leaving farmers with limited options for managing nematode infestation
Externí odkaz:
https://doaj.org/article/609af50dc9664af39474ef0017566555
Autor:
Mary M. McDermott, Christopher R. Martens, Kathryn J. Domanchuk, Dongxue Zhang, Clara B. Peek, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Karen J. Ho, Melina R. Kibbe, Kate Kosmac, Donald Lloyd-Jones, Charlotte A. Peterson, Robert Sufit, Lu Tian, Stephanie Wohlgemuth, Lihui Zhao, Pei Zhu, Christiaan Leeuwenburgh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance. NAD+ reduces oxidative stress and is an essential cofactor for mitochondrial respirat
Externí odkaz:
https://doaj.org/article/2c373f254eb346318d878694e2b1a44e
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThere are increasing reports of the misuse of prescription psychostimulants for cognitive enhancement together with recreational cannabis. This raises a concern that chronic use of cannabis high in Δ9-THC may alter the sensitivity to amphe
Externí odkaz:
https://doaj.org/article/f727d7ba3aa846f99d4bbeb35c235fa5
Publikováno v:
Journal of Obstetric Anaesthesia and Critical Care, Vol 14, Iss 2, Pp 170-172 (2024)
Gestational thrombocytopenia, preeclampsia, and immune thrombocytopenia are commonly recognized etiologies of low platelet counts representing the vast majority of encountered gestational cases (86-100%). However, there are many other rare causes. Th
Externí odkaz:
https://doaj.org/article/75f2679c47d04522b0edf90878a22838
Autor:
Rita K Hayford, Olivia C Haley, Ethalinda K Cannon, John L Portwood, Jack M Gardiner, Carson M Andorf, Margaret R Woodhouse
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Environmental stress factors, such as biotic and abiotic stress, are becoming more common due to climate variability, significantly affecting global maize yield. Transcriptome profiling studies provide insights into the molecular
Externí odkaz:
https://doaj.org/article/802466f5e32a471eb5f4a9fb37411d24
Autor:
Yu Wang, Sylvia A. Sapula, Jonathan J. Whittall, Jack M. Blaikie, Olga Lomovskaya, Henrietta Venter
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The increasing rate of carbapenem-resistant bacteria within healthcare environments is an issue of great concern that needs urgent attention. This resistance is driven by metallo-β-lactamases (MBLs), which can catalyse the hydrolysis of alm
Externí odkaz:
https://doaj.org/article/e0df035d35574827b2da512d0a7645c5
Autor:
Kayonda Hubert Ngamaba, Laddy Sedzo Lombo, Israël Kenda Makopa, Martin Webber, Jack M. Liuta, Joule Ntwan Madinga, Samuel Ma Miezi Mampunza, Cheyann Heap
Publikováno v:
npj Mental Health Research, Vol 3, Iss 1, Pp 1-16 (2024)
Abstract In the Democratic Republic of the Congo (DRC), the prevalence of mental health issues could be greater than in other low-income and middle-income countries because of major risk factors related to armed conflicts and poverty. Given that ment
Externí odkaz:
https://doaj.org/article/857bcf61b6f042f190493b781299de2a