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of 3
pro vyhledávání: '"Jack Lopuszynski"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 4088 (2024)
One of the bottlenecks to bringing new therapies to the clinic has been a lack of vectors for delivering novel therapeutics in a targeted manner. Cell penetrating peptides (CPPs) have received a lot of attention and have been the subject of numerous
Externí odkaz:
https://doaj.org/article/921325dae9b1445daa99f0ceea2b7a48
Autor:
Maliha Zahid, Beth Weber, Ray Yurko, Kazi Islam, Vaishavi Agrawal, Jack Lopuszynski, Hisato Yagi, Guy Salama
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2107 (2023)
Background: Amiodarone is underutilized due to significant off-target toxicities. We hypothesized that targeted delivery to the heart would lead to the lowering of the dose by utilizing a cardiomyocyte-targeting peptide (CTP), a cell-penetrating pept
Externí odkaz:
https://doaj.org/article/4715d0ab7cca4914b0c2ebd9d5b30beb
Publikováno v:
Medical Research Archives. 10
Cell penetrating peptides (CPPs) offer unique and promising solutions to overcome barriers to intracellular delivery of potential therapeutics for a variety of diseases, particularly when used as a delivery method for RNA interference agents such as