Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jack Littrell"'
Autor:
Linda Berg Luecke, Matthew Waas, Jack Littrell, Melinda Wojtkiewicz, Chase Castro, Maria Burkovetskaya, Erin N. Schuette, Amanda Rae Buchberger, Jared M. Churko, Upendra Chalise, Michelle Waknitz, Shelby Konfrst, Roald Teuben, Justin Morrissette-McAlmon, Claudius Mahr, Daniel R. Anderson, Kenneth R. Boheler, Rebekah L. Gundry
Publikováno v:
Nature Cardiovascular Research. 2:76-95
Cardiac cell surface proteins are drug targets and useful biomarkers for discriminating among cellular phenotypes and disease states. Here we developed an analytical platform, CellSurfer, that enables quantitative cell surface proteome (surfaceome) p
Autor:
Jack Littrell, Chase Castro, Matthew Waas, Maia I. Kelly, Ellen Poon, Rebekah L. Gundry, Mustafa Albahrani, Kenneth R. Boheler, Bin Yan
Publikováno v:
Pflugers Archiv
Pflugers Arch
Pflugers Arch
Proper protein glycosylation is critical to normal cardiomyocyte physiology. Aberrant glycosylation can alter protein localization, structure, drug interactions, and cellular function. The in vitro differentiation of human pluripotent stem cells into
Publikováno v:
J Am Soc Mass Spectrom
Cell surface transmembrane, extracellular, and secreted proteins are high value targets for immunophenotyping, drug development, and studies related to intercellular communication in health and disease. As the number of specific and validated affinit
Autor:
Rachel A. Jones Lipinski, Rebekah L. Gundry, Matthew Waas, Polly A. Hansen, Shana T. Snarrenberg, Jack Littrell, John A. Corbett
Publikováno v:
Bioinformatics
Motivation Cell-type-specific surface proteins can be exploited as valuable markers for a range of applications including immunophenotyping live cells, targeted drug delivery and in vivo imaging. Despite their utility and relevance, the unique combin
Autor:
Rebekah L. Gundry, Jack Littrell, Chase Castro, Maia I. Kelly, Matthew Waas, Kenneth R. Boheler, Mustafa Albahrani, Ellen Poon, Bin Yan
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 473:1167-1167
Autor:
Rebekah L. Gundry, Rachel A. Jones Lipinski, John A. Corbett, Polly A. Hansen, Matthew Waas, Shana T. Snarrenberg, Jack Littrell
MotivationCell-type specific surface proteins can be exploited as valuable markers for a range of applications including immunophenotyping live cells, targeted drug delivery, and in vivo imaging. Despite their utility and relevance, the unique combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bcac22df20f7794bdf898b69d5132a
Autor:
Christy B. Erbe, Christina L. Runge, Joseph E. Kerschner, Gabor T. Marth, David R. Friedland, Wai-Meng Kwok, Regina Cole, Kate Merath, Roland James, Amit Indap, Ericka King, Harald H H Göring, Jack Littrell, Jack W. Kent, Michael Olivier, Yifan Zhou, Franz Rüschendorf, Norbert Hubner
Publikováno v:
JAMA otolaryngology-- headneck surgery. 142(9)
Importance Sensorineural hearing loss (SNHL) is commonly caused by conditions that affect cochlear structures or the auditory nerve, and the genes identified as causing SNHL to date only explain a fraction of the overall genetic risk for this debilit
Autor:
Yi Zhang, Ann DeLaForest, Gabriele E. Sonnenberg, Erin MacKinney, Russell A. Wilke, Jennifer Gunnell, Jack Littrell, Cecilia J. Hillard, Ahmed H. Kissebah, Tesfaye M. Baye, Michael Olivier
Publikováno v:
Pharmacogenomics. 10:1929-1939
A more thorough understanding of the genetic architecture underlying obesity-related lipid disorders could someday facilitate cardiometabolic risk reduction through early clinical intervention based upon improved characterization of individual risk.
Publikováno v:
Genomics, Proteomics & Bioinformatics
High-throughput SNP genotyping platforms use automated genotype calling algorithms to assign genotypes. While these algorithms work efficiently for individual platforms, they are not compatible with other platforms, and have individual biases that re
Autor:
Jack Littrell, J. Eckert, Michael Olivier, Regina Cole, Xujing Wang, Edward M. Smith, Ahmed H. Kissebah
Publikováno v:
Genomics. 88(4):407-414
The International HapMap Consortium has determined the linkage disequilibrium (LD) patterns of four major human populations. The aim of our investigation was to compare the LD patterns of the HapMap CEPH (Centre d'Etude du Polymorphisme Humain) sampl