Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jack L. Radomski"'
Autor:
Jack L. Radomski, Geoffrey Woodard
Publikováno v:
Journal of the American Pharmaceutical Association. American Pharmaceutical Association. 35(10)
By making use of a modified voluntary ingestion procedure, the dosage‐mortality curves for both male and female rats were determined for 4 red squill standards of widely varying potency. The ratio of the LD 50 's for males to the LD 50 's for femal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41b839b4897bed14221151852a14381
https://pubmed.ncbi.nlm.nih.gov/21002911
https://pubmed.ncbi.nlm.nih.gov/21002911
Autor:
Jack L. Radomski
Publikováno v:
Annual Review of Pharmacology. 14:127-137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::928c0e2cfa3a3ef8198706ec64daf2af
https://doi.org/10.1146/annurev.pa.14.040174.001015
https://doi.org/10.1146/annurev.pa.14.040174.001015
Publikováno v:
Cancer Letters. 11:309-313
The glucuronic acid conjugate of N-hydroxy-4-aminobiphenyl was tested for carcinogenicity using a heterotopically transplanted rat urinary bladder (HTB) diverted from urine flow. A low-grade transitional cell carcinoma developed in 1 of 16 HTB and sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b68ae1044b77cc7d5425a9ab0813d6
https://doi.org/10.1016/0304-3835(81)90096-3
https://doi.org/10.1016/0304-3835(81)90096-3
Publikováno v:
CRC Critical Reviews in Toxicology. 6:81-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98236ab886d03b341bf52f90b36af55
https://doi.org/10.3109/10408447909113047
https://doi.org/10.3109/10408447909113047
Publikováno v:
JNCI: Journal of the National Cancer Institute. 60:327-333
So that the earliest morphologic changes produced in dog bladders by a bladder carcinogen could be detected, 25 mg 2-naphthylamine/kg was given daily to dogs for 1, 6, and 36 weeks. Among early changes observed in some, but not all, dogs at 1 and 6 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da2aa71342546d78cdc1cdaebff5fa0c
https://doi.org/10.1093/jnci/60.2.327
https://doi.org/10.1093/jnci/60.2.327
Publikováno v:
Toxicology and Applied Pharmacology. 50:479-484
Glucuronide conjugates of carcinogenic N -hydroxy metabolites of the primary aromatic amines, 4-aminobiphenyl (4-ABP), 2-naphthylamine (2-NA), and 1-naphthylamine (1-NA) were isolated from the urine of dogs administered the respective primary amine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cb7aec0a32f84f4b0c4e736ed013c2
https://doi.org/10.1016/0041-008x(79)90401-0
https://doi.org/10.1016/0041-008x(79)90401-0
Publikováno v:
JNCI: Journal of the National Cancer Institute. 58:1831-1834
Administration of a dietary supplement of 6 g D,L tryptophan/day for 4 1/2 years following the administration of a single dose of 50 mg 4-aminobiphenyl/kg produced a bladder tumor in 1 of 4 beagle dogs. No tumors were observed in 6 dogs given the sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b88503613a2d4f0441a3c6cadb45609
https://doi.org/10.1093/jnci/58.6.1831
https://doi.org/10.1093/jnci/58.6.1831
Publikováno v:
Toxicology and Applied Pharmacology. 7:122-127
An experiment was conducted in which male and female mice of four different strains, namely DBA, Swiss, C3H, and C57 black were fed for the duration of their life a mixture of foods (fruit compote, beef, tuna fish, sweet potato, and corn), all of whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e8f40136986559723a4c8a9fc217db5
https://doi.org/10.1016/0041-008x(65)90083-9
https://doi.org/10.1016/0041-008x(65)90083-9
Publikováno v:
Toxicology and Applied Pharmacology. 7:113-121
Beef stew (C-ration) and evaporated milk, irradiated at levels of 2.79 and 5.58 megarads were fed to rats and to dogs as 35% of their diets for a period of two years. Fat-soluble vitamins were administered separately to both species. Nonirradiated be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35ef593f2ee78e53c11bd5196bd8e44
https://doi.org/10.1016/0041-008x(65)90082-7
https://doi.org/10.1016/0041-008x(65)90082-7
Publikováno v:
JNCI: Journal of the National Cancer Institute. 50:989-995
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12c6035a01f21ac6d3f25af1200b2ab2
https://doi.org/10.1093/jnci/50.4.989
https://doi.org/10.1093/jnci/50.4.989