Zobrazeno 1 - 10
of 5 218
pro vyhledávání: '"Jack K"'
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 3238-3247 (2024)
Externí odkaz:
https://doaj.org/article/218208b62d4042958f0f869f7281d636
Autor:
Rodion Isakovich, Valerie C. Cates, Brandon A. Pentz, Jordan D. Bird, Emily R. Vanden Berg, Emily M. deFreitas, Cassandra E. Nysten, Jack K. Leacy, Ken D. O'Halloran, Thomas D. Brutsaert, Mingma T. Sherpa, Trevor A. Day
Publikováno v:
Experimental Physiology, Vol 109, Iss 7, Pp 1080-1098 (2024)
Abstract High altitude (HA) ascent imposes systemic hypoxia and associated risk of acute mountain sickness. Acute hypoxia elicits a hypoxic ventilatory response (HVR), which is augmented with chronic HA exposure (i.e., ventilatory acclimatization; VA
Externí odkaz:
https://doaj.org/article/015f1fa224b34a7c904e7ebe5a7e43ca
Autor:
Jack K. Donohue, Danielle S. Gruen, Nidhi Iyanna, John M. Lorence, Joshua B. Brown, Francis X. Guyette, Brian J. Daley, Brian J. Eastridge, Richard S. Miller, Raminder Nirula, Brian G. Harbrecht, Jeffrey A. Claridge, Herb A. Phelan, Gary A. Vercruysse, Terence O’Keeffe, Bellal Joseph, Matthew D. Neal, Timothy R. Billiar, Jason L. Sperry
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Injury mechanism is an important consideration when conducting clinical trials in trauma. Mechanisms of injury may be associated with differences in mortality risk and immune response to injury, impacting the potential success of the trial.
Externí odkaz:
https://doaj.org/article/fb736ecef55a4e4d8e607f38370a6f96
Publikováno v:
IEEE Access, Vol 12, Pp 11378-11387 (2024)
The critical current in a one-dimensional (1D) crossed-field gap is defined by the transition from a cycloidal flow to a near-Brillouin (nB) state characterized by electron flow orthogonal to both the electric and magnetic fields and uniform virtual
Externí odkaz:
https://doaj.org/article/f7998a84058f45a1b457ee1d3b71f3b3
Autor:
Bellal Joseph, Raminder Nirula, Brian J Eastridge, Jason L Sperry, Gary Vercruysse, Francis X Guyette, Joshua B Brown, Richard S Miller, Brian G Harbrecht, Herb A Phelan, Matthew D Neal, Jack K Donohue, Nidhi Iyanna, John M Lorence, Terence O'Keeffe, Jeffrey A Claridge, Elizabeth Gimbel, Brian J Daley
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss 1 (2024)
Background The reporting of adverse events (AEs) is required and well defined in the execution of clinical trials, but is poorly characterized particularly in prehospital trials focusing on traumatic injury. In the setting of prehospital traumatic in
Externí odkaz:
https://doaj.org/article/b85cd3a6c6fb4d58bf1919d3111354b5
Autor:
Bellal Joseph, Raminder Nirula, Brian J Eastridge, Jason L Sperry, Joshua B Brown, Matthew D Neal, Gary A Vercruysse, Jack K Donohue, Nidhi Iyanna, John M Lorence, Frances X Guyette, Terence O'Keeffe
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss 1 (2024)
Background Tranexamic acid (TXA) has been hypothesized to mitigate coagulopathy in patients after traumatic injury. Despite previous prehospital clinical trials demonstrating a TXA survival benefit, none have demonstrated correlated changes in thromb
Externí odkaz:
https://doaj.org/article/57965e24b9a949b5ac468d7df743f619
Autor:
Benedikt Goretzki, Christoph Wiedemann, Brett A. McCray, Stefan L. Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K. Donohue, Cy M. Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J. Sumner, Gerhard Hummer, Ute A. Hellmich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large
Externí odkaz:
https://doaj.org/article/164d0c141a984b619e153ae313a859dd
Autor:
Jack K. Donohue, Jason L. Sperry, Philip C. Spinella, Darrell J. Triulzi, Christine L. Leeper, Mark H. Yazer
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTBackground The introduction of low titer group O whole blood (LTOWB) that contains potentially ABO-incompatible plasma and the increasing use of group A plasma, due to shortages of AB plasma, in trauma patients whose ABO group is unknown coul
Externí odkaz:
https://doaj.org/article/d92c028323ad491e8b8ba4a3ec042216
Autor:
Jack K. Donohue, Eric J. Hyzny, Sarah Clifford, Ernest G. Chan, Jenalee Nicole Coster, Masashi Furukawa, Pablo G. Sanchez
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 22, p 7028 (2023)
Background: With new variants challenging the effectiveness of preventive measures, we are beginning to recognize the reality that COVID-19 will continue to pose an endemic threat. The manifestations of COVID-19 in lung transplant recipients during i
Externí odkaz:
https://doaj.org/article/5f62e3c7152a484f947e56313d1060c8
Autor:
Jack K. S. Möller, Kinga Linowiecka, Maciej Gagat, Anna A. Brożyna, Marek Foksiński, Agnieszka Wolnicka-Glubisz, Elżbieta Pyza, Russel J. Reiter, Meri K. Tulic, Andrzej T. Slominski, Kerstin Steinbrink, Konrad Kleszczyński
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14947 (2023)
Melatonin (N-acetyl-5-methoxytryptamine, MEL), its kynurenic (N1-acetyl-N2-formyl-5-methoxykynurenine, AFMK) and indolic derivatives (6-hydroxymelatonin, 6(OH)MEL and 5-methoxytryptamine, 5-MT) are endogenously produced in human epidermis. Melatonin,
Externí odkaz:
https://doaj.org/article/d3f3ebafbb9d4d1ebbbdb53a90b8a928