Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jack Jhamandas"'
Autor:
Rania Soudy, Ryoichi Kimura, Aarti Patel, Wen Fu, Kamaljit Kaur, David Westaway, Jing Yang, Jack Jhamandas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/3654b8933c2a4e488728abfc7f4098ef
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Extracellular vesicles (EVs) are double membrane structures released by all cell types with identified roles in the generation, transportation, and degradation of amyloid-β protein (Aβ) oligomers in Alzheimer’s disease (AD). EVs are thus increasi
Externí odkaz:
https://doaj.org/article/c8e10a580cea4e278ea7bc37b0f8690f
Autor:
Jennifer Croden, Josue Rodrigues Silva, Wenlong Huang, Nancy Gupta, Wen Fu, Kaja Matovinovic, Mazzen Black, Xian Li, Kunsong Chen, Yulian Wu, Jack Jhamandas, Gina R Rayat
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258208 (2021)
Islet transplantation is being considered as an alternative treatment for type 1 diabetes. Despite recent progress, transplant recipients continue to experience progressive loss of insulin independence. Cyanidin-3-O-Glucoside (C3G) has shown to be pr
Externí odkaz:
https://doaj.org/article/b9c73ac7b4974340bc4a9c3c8adefc23
Autor:
Wen Fu, Vlatka Vukojevic, Aarti Patel, Rania Soudy, David MacTavish, David Westaway, Kamaljit Kaur, Valeri Goncharuk, Jack Jhamandas
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Background Neuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer’s disease (AD) pathology. Amyloid beta (Aβ) protein is known to activate microglia and unleash an inflammator
Externí odkaz:
https://doaj.org/article/9a9fa02c523c4fa99cf9b49d41312e22
Autor:
Janelle N, Fawver, Yonatan, Ghiwot, Catherine, Koola, Wesley, Carrera, Jennifer, Rodriguez-Rivera, Caterina, Hernandez, Kelly T, Dineley, Yu, Kong, Jianrong, Li, Jack, Jhamandas, George, Perry, Ian V J, Murray
Publikováno v:
Current Alzheimer research. 11(10)
Amyloid formation is the pathological hallmark of type 2 diabetes (T2D) and Alzheimer's disease (AD). These diseases are marked by extracellular amyloid deposits of islet amyloid polypeptide (IAPP) in the pancreas and amyloid β (Aβ) in the brain. S
Autor:
Yohannes, Haile, Wen, Fu, Beipei, Shi, David, Westaway, Glen, Baker, Jack, Jhamandas, Fabrizio, Giuliani
Publikováno v:
Journal of neuroscience research. 92(9)
Primary human fetal neurons and astrocytes (HFNs and HFAs, respectively) provide relevant cell types with which to study in vitro the mechanisms involved in various human neurological diseases, such as multiple sclerosis, Parkinson's disease, and Alz