Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jack Jansma"'
Autor:
Jack Jansma, Nicola U. Thome, Markus Schwalbe, Anastasia Chrysovalantou Chatziioannou, Somayah S. Elsayed, Gilles P. van Wezel, Pieter van den Abbeele, Saskia van Hemert, Sahar El Aidy
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTThe gut microbiota plays a pivotal role in health and disease. The use of probiotics as microbiota-targeted therapies is a promising strategy to improve host health. However, the molecular mechanisms involved in such therapies are often not w
Externí odkaz:
https://doaj.org/article/aefc9eaf089d4395beb16aea36d020a3
Autor:
Jack Jansma, Anastasia Chrysovalantou Chatziioannou, Kitty Castricum, Saskia van Hemert, Sahar El Aidy
Publikováno v:
mSystems, Vol 8, Iss 5 (2023)
ABSTRACT The gut microbiota plays a crucial role in maintaining overall health and probiotics have emerged as a promising microbiota-targeted therapy for improving human health. However, the molecular mechanisms of probiotics action in general and th
Externí odkaz:
https://doaj.org/article/3cc32c7d07664d82b26067ea9c832bd1
Autor:
Jack Jansma, Sahar El Aidy
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract The human gut harbors an enormous number of symbiotic microbes, which is vital for human health. However, interactions within the complex microbiota community and between the microbiota and its host are challenging to elucidate, limiting dev
Externí odkaz:
https://doaj.org/article/d3db0d50099b4c088d997b240927e539
Autor:
Jack Jansma, Nicola U. Thome, Markus Schwalbe, Anastasia Chrysovalantou Chatziioannou, Somayah S. Elsayed, Gilles P. van Wezel, Pieter van den Abbeele, Saskia van Hemert, Sahar El Aidy
The gut microbiota plays a pivotal role in health and disease. The use of probiotics as microbiota-targeted therapies is a promising strategy to improve host health. However, dynamic molecular mechanisms are often not elucidated, especially when targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ade563a261d3a11f36325f0a8d1aceb
https://doi.org/10.1101/2023.01.29.525861
https://doi.org/10.1101/2023.01.29.525861
Autor:
Sjors Maassen, Harry Warner, Melina Ioannidis, Jack Jansma, Hugo Markus, Sahar El Aidy, María-Dolores Chiara, Jose Luis Chiara, Larissa Maierhofer, Helen Weavers, Geert van den Bogaart
Publikováno v:
Free Radic. Biol. Med.
Weavers, H 2022, ' Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages. ', Free Radical Biology and Medicine, vol. 188, pp. 287-297 . https://doi.org/10.1016/j.freeradbiomed.2022.06.235
Free Radical Biology and Medicine, 188:202206235, 287-297. ELSEVIER SCIENCE INC
Weavers, H 2022, ' Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages. ', Free Radical Biology and Medicine, vol. 188, pp. 287-297 . https://doi.org/10.1016/j.freeradbiomed.2022.06.235
Free Radical Biology and Medicine, 188:202206235, 287-297. ELSEVIER SCIENCE INC
5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is uncle
Autor:
Rogier van Essen, Anastasia Chrysovalantou Chatziioannou, Iris E. C. Sommer, Sahar El Aidy, Saskia van Hemert, Bartholomeus C M Haarman, Jenny Borkent, Jack Jansma, Magdalini Ioannou
Publikováno v:
Journal of Psychiatric Research, 151, 507-515. PERGAMON-ELSEVIER SCIENCE LTD
The brain-gut axis is increasingly recognized as an important contributing factor in the onset and progression of severe mental illnesses such as schizophrenia spectrum disorders and bipolar disorder. This study investigates associations between leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54d44778b471e08c3c6b64392eeb2ff
https://doi.org/10.1101/2021.12.01.21267133
https://doi.org/10.1101/2021.12.01.21267133
Autor:
Sahar El Aidy, Jack Jansma
Publikováno v:
Microbiome
Microbiome, Vol 9, Iss 1, Pp 1-14 (2021)
Microbiome, Vol 9, Iss 1, Pp 1-14 (2021)
The human gut harbors an enormous number of symbiotic microbes, which is vital for human health. However, interactions within the complex microbiota community and between the microbiota and its host are challenging to elucidate, limiting development
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 106:110169. PERGAMON-ELSEVIER SCIENCE LTD
The endocannabinoid system is a metabolic pathway involved in the communication between the gut microbiota and the host. In the gut, the endocannabinoid system regulates the integrity of the intestinal barrier. A compromised integrity of the intestin