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of 5
pro vyhledávání: '"Jack Hermsen"'
Autor:
Jack Hermsen, Bryan Hambley
Publikováno v:
Cancers, Vol 15, Iss 13, p 3477 (2023)
Acute promyelocytic leukemia (APL) has a well-established mechanism and a long-term prognosis that exceeds that of any other acute leukemia. These improving outcomes are due, in part, to all-trans retinoic acid (ATRA) and arsenic trioxide (ATO), two
Externí odkaz:
https://doaj.org/article/bc670b8b15d74eb186971fd5e421ee7b
Autor:
Jack Hermsen, Matthew E. Brown
Publikováno v:
Curr Protoc Stem Cell Biol
New human pluripotent stem cell (hPSC)-derived therapies are advancing to clinical trials at an increasingly rapid pace. In addition to ensuring that the therapies function properly, there is a critical need to investigate the human immune response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78ea221eda79ebac66bd5196dd1e2d7
https://europepmc.org/articles/PMC7436941/
https://europepmc.org/articles/PMC7436941/
Autor:
Wendy C. Crone, Adriana M. Rodriguez, Timothy J. Kamp, William J. Burlingham, Wenxuan Cai, Luke Profio, Mitch Biermann, Brett N. Napiwocki, Matthew E. Brown, Dona Greta Isai, Di Lang, Tianxiao Han, Ying Ge, Annie Shao, Marites T. Woon, Jack Hermsen, Alexey V. Glukhov, Timothy A. Hacker, Donglim Esther Park, Ying Zhou, Andras Czirok
Publikováno v:
Stem Cells
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to promote cardiomyocyte maturation have focused interventions on differentiated hPSC-CMs, but this
Autor:
Mitch Biermann, Wenxuan Cai, Di Lang, Jack Hermsen, Luke Profio, Annie Shao, Tianxiao Han, Marites Woon, Alexey Glukhov, Ying Ge, Timothy J Kamp
Publikováno v:
Circulation. 138
Cardiomyocytes derived from human induced pluripotent stem cells (hiPS-CMs) hold promise for disease modeling, drug discovery, and therapy, but the challenge remains to create mature cardiomyocytes like those found in the adult heart. While groups ha
Autor:
Virginia Tuncel, Jack Hermsen, Robert Laughlin, Mark T. McNally, T.J. Davis, Michael Weeden, David Sampe, Justin Johnson, Brett Poniewaz, Maurice Lucre, Evan Bruss, Gina Wade, Chad Marable
Publikováno v:
The FASEB Journal. 29
Human cells have the remarkable capability to regulate protein production by degrading target mRNA by two pathways: RNA interference (RNAi) and micro RNA (miRNA). Central to these pathways is the protein Argonaute-2 (Ago-2). In the RNAi pathway, smal