Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Jack Gauldie"'
Autor:
Tina Bormann, Regina Maus, Jennifer Stolper, Meritxell Tort Tarrés, Christina Brandenberger, Dirk Wedekind, Danny Jonigk, Tobias Welte, Jack Gauldie, Martin Kolb, Ulrich A. Maus
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung interstitium, which contributes to substantial morbidity and mortal
Externí odkaz:
https://doaj.org/article/21db241c974f480aaaa03111058bc8f0
Autor:
Mark G Jones, Orestis G Andriotis, James JW Roberts, Kerry Lunn, Victoria J Tear, Lucy Cao, Kjetil Ask, David E Smart, Alessandra Bonfanti, Peter Johnson, Aiman Alzetani, Franco Conforti, Regan Doherty, Chester Y Lai, Benjamin Johnson, Konstantinos N Bourdakos, Sophie V Fletcher, Ben G Marshall, Sanjay Jogai, Christopher J Brereton, Serena J Chee, Christian H Ottensmeier, Patricia Sime, Jack Gauldie, Martin Kolb, Sumeet Mahajan, Aurelie Fabre, Atul Bhaskar, Wolfgang Jarolimek, Luca Richeldi, Katherine MA O'Reilly, Phillip D Monk, Philipp J Thurner, Donna E Davies
Publikováno v:
eLife, Vol 7 (2018)
Matrix stiffening with downstream activation of mechanosensitive pathways is strongly implicated in progressive fibrosis; however, pathologic changes in extracellular matrix (ECM) that initiate mechano-homeostasis dysregulation are not defined in hum
Externí odkaz:
https://doaj.org/article/2541e80c33c2458ba21e589aed967251
Autor:
Amanda L Tatler, Amanda T Goodwin, Olumide Gbolahan, Gauri Saini, Joanne Porte, Alison E John, Rachel L Clifford, Shelia M Violette, Paul H Weinreb, Helen Parfrey, Paul J Wolters, Jack Gauldie, Martin Kolb, Gisli Jenkins
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0158047 (2016)
Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive disease with poor survival rates and limited treatment options. Upregulation of αvβ6 integrins within the alveolar epithelial cells is a characteristic feature of IPF and correlates
Externí odkaz:
https://doaj.org/article/d277082847c747f6b1228aba08233da2
Autor:
Daniela Damjanovic, Amandeep Khera, Maria Fe Medina, Jane Ennis, Jeffrey D Turner, Jack Gauldie, Zhou Xing
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Pneumococcal infections are the leading cause of community-acquired pneumonia. Although the type 1 interferon-α (IFN-α) is a well-known antiviral cytokine, the role of IFN-α in antipneumococcal host defense and its therapeutic potential remain poo
Externí odkaz:
https://doaj.org/article/f149ddf9d8044f6c8ad66a1682e41a0a
Publikováno v:
Canadian Respiratory Journal, Vol 4, Iss 4, Pp 205-210 (1997)
OBJECTIVES: To compare numbers of myofibroblasts, a fibroblast phenotype associated with chronically inflamed tissue, in nasal polyp tissues from untreated and corticosteroid-treated subjects. To study whether corticosteroids can directly affect myof
Externí odkaz:
https://doaj.org/article/8133aca7313f44489145bf36a6e61054
Autor:
Christina M Carlson, Elizabeth A Turpin, Lindsey A Moser, Kevin B O'Brien, Troy D Cline, Jeremy C Jones, Terrence M Tumpey, Jacqueline M Katz, Laura A Kelley, Jack Gauldie, Stacey Schultz-Cherry
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001136 (2010)
Transforming growth factor-beta (TGF-β), a multifunctional cytokine regulating several immunologic processes, is expressed by virtually all cells as a biologically inactive molecule termed latent TGF-β (LTGF-β). We have previously shown that TGF-
Externí odkaz:
https://doaj.org/article/c914a8ab6375431794ca62e848a92eeb
Autor:
Jeffrey E. Green, Jack Gauldie, R. Mark Simpson, Shelley Hoover, Joshua D. Webster, Anne Sally Davis, Isabel Chu, Jane Ann Smith, Aleksandra M. Michalowski, Lara H. El Touny, Dalit Barkan
Supplementary Figure Legend 2 from Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02888705471ba560c35f602d2fc8575e
https://doi.org/10.1158/0008-5472.22383681
https://doi.org/10.1158/0008-5472.22383681
Autor:
Jeffrey E. Green, Jack Gauldie, R. Mark Simpson, Shelley Hoover, Joshua D. Webster, Anne Sally Davis, Isabel Chu, Jane Ann Smith, Aleksandra M. Michalowski, Lara H. El Touny, Dalit Barkan
Supplementary Figure 6 from Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ba8f391557703856283f3a03ed9140
https://doi.org/10.1158/0008-5472.22383690.v1
https://doi.org/10.1158/0008-5472.22383690.v1
Autor:
Jeffrey E. Green, Jack Gauldie, R. Mark Simpson, Shelley Hoover, Joshua D. Webster, Anne Sally Davis, Isabel Chu, Jane Ann Smith, Aleksandra M. Michalowski, Lara H. El Touny, Dalit Barkan
Breast cancer that recurs as metastatic disease many years after primary tumor resection and adjuvant therapy seems to arise from tumor cells that disseminated early in the course of disease but did not develop into clinically apparent lesions. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160176f2ec020ef77662f56f71a13ded
https://doi.org/10.1158/0008-5472.c.6500634.v1
https://doi.org/10.1158/0008-5472.c.6500634.v1
Autor:
Jeffrey E. Green, Jack Gauldie, R. Mark Simpson, Shelley Hoover, Joshua D. Webster, Anne Sally Davis, Isabel Chu, Jane Ann Smith, Aleksandra M. Michalowski, Lara H. El Touny, Dalit Barkan
Supplementary Methods from Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dabe21f58f190597014aacbf79ff983
https://doi.org/10.1158/0008-5472.22383672
https://doi.org/10.1158/0008-5472.22383672