Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jack F Cazet"'
Publikováno v:
eLife, Vol 10 (2021)
During whole-body regeneration, a bisection injury can trigger two different types of regeneration. To understand the transcriptional regulation underlying this adaptive response, we characterized transcript abundance and chromatin accessibility duri
Externí odkaz:
https://doaj.org/article/646315c0bf5b478ca4e24c390962312c
Autor:
Jack F. Cazet, Stefan Siebert, Hannah Morris Little, Philip Bertemes, Abby S. Primack, Peter Ladurner, Matthias Achrainer, Mark T. Fredriksen, R. Travis Moreland, Sumeeta Singh, Suiyuan Zhang, Tyra G. Wolfsberg, Christine E. Schnitzler, Andreas D. Baxevanis, Oleg Simakov, Bert Hobmayer, Celina E. Juliano
Publikováno v:
Genome Research. 33:283-298
The epithelial and interstitial stem cells of the freshwater polypHydraare the best-characterized stem cell systems in any cnidarian, providing valuable insight into cell type evolution and the origin of stemness in animals. However, little is known
Autor:
Abby S Primack, Jack F Cazet, Hannah Morris Little, Susanne Mühlbauer, Ben D Cox, Charles N David, Jeffrey A Farrell, Celina E Juliano
Publikováno v:
bioRxiv
The small freshwater cnidarian polypHydra vulgarisuses adult stem cells (interstitial stem cells) to continually replace neurons throughout its life. This feature, combined with the ability to image the entire nervous system (Badhiwala et al., 2021;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a251fa7b52ba8e9e638859e94e83977
https://doi.org/10.1101/2023.03.15.531610
https://doi.org/10.1101/2023.03.15.531610
Autor:
Jack F. Cazet, Stefan Siebert, Hannah Morris Little, Philip Bertemes, Abby S. Primack, Peter Ladurner, Matthias Achrainer, Mark T. Fredriksen, R. Travis Moreland, Sumeeta Singh, Suiyuan Zhang, Tyra G. Wolfsberg, Christine E. Schnitzler, Andreas D. Baxevanis, Oleg Simakov, Bert Hobmayer, Celina E. Juliano
The epithelial and interstitial stem cells of the freshwater polyp Hydra are the best characterized stem cell systems in any cnidarian, providing valuable insight into cell type evolution and the origin of stemness in animals. However, little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500030d32f05e6ef89d51898d81980fb
https://doi.org/10.1101/2022.06.21.496857
https://doi.org/10.1101/2022.06.21.496857
Publikováno v:
RNA. 26:550-563
Transposable elements (TEs) can damage genomes, thus organisms use a variety of mechanisms to repress TE expression. The PIWI–piRNA pathway is a small RNA pathway that represses TE expression in the germline of animals. Here we explore the function
Differential gene regulation in DAPT-treated Hydra reveals candidate direct Notch signalling targets
Autor:
Andrea Prexl, Qin Pan, Celina E. Juliano, Stefan Krebs, Stefan Siebert, Angelika Böttger, Jack F Cazet, Jasmin Moneer
Publikováno v:
J Cell Sci
In Hydra, Notch inhibition causes defects in head patterning and prevents differentiation of proliferating nematocyte progenitor cells into mature nematocytes. To understand the molecular mechanisms by which the Notch pathway regulates these processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac98b9a025043f2b0bb1a3384f346755
https://europepmc.org/articles/PMC8353520/
https://europepmc.org/articles/PMC8353520/
Autor:
Jack F Cazet, Jasmin Moneer, Andrea Prexl, Celina E. Juliano, Stefan Siebert, Pan Q, Stefan Krebs, Angelika Böttger
The Notch pathway is highly conserved and essential for animal development. We investigated the function of Notch-signalling inHydraby using the presenilin inhibitor DAPT, which efficiently blocks propagation of Notch-signals. InHydra, DAPT treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8380496e098d7331c1b94ca95ca6ee7b
https://doi.org/10.1101/2021.02.09.430419
https://doi.org/10.1101/2021.02.09.430419
Publikováno v:
RNA (New York, N.Y.), vol 26, iss 5
Transposable elements (TEs) can damage genomes, thus organisms employ a variety of mechanisms to repress TE expression. However, these mechanisms often fail over time leading to de-repression of TEs in aging tissues. The PIWI-piRNA pathway is a small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23d7a438cbb9c48c3d8a9a37b405f56
https://escholarship.org/uc/item/7rf489pv
https://escholarship.org/uc/item/7rf489pv
Publikováno v:
RNA
Transposable elements (TEs) can damage genomes, thus organisms use a variety of mechanisms to repress TE expression. The PIWI–piRNA pathway is a small RNA pathway that represses TE expression in the germline of animals. Here we explore the function