Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jack E, Teasdale"'
Autor:
Laura J, Corbin, Stephen J, White, Amy E, Taylor, Christopher M, Williams, Kurt, Taylor, Marion T, van den Bosch, Jack E, Teasdale, Matthew, Jones, Mark, Bond, Matthew T, Harper, Louise, Falk, Alix, Groom, Georgina G J, Hazell, Lavinia, Paternoster, Marcus R, Munafò, Børge G, Nordestgaard, Anne, Tybjærg-Hansen, Stig E, Bojesen, Caroline, Relton, Josine L, Min, George, Davey Smith, Andrew D, Mumford, Alastair W, Poole, Nicholas J, Timpson
Publikováno v:
Circulation research. 130(3)
DNA hypomethylation at theWe conducted multiple independent experiments to assess whether DNA hypomethylation atObservationally, DNA methylation atSmoking-induced epigenetic DNA hypomethylation at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0e2e1314b8e9d9393c96726078206ff
https://pubmed.ncbi.nlm.nih.gov/35012325
https://pubmed.ncbi.nlm.nih.gov/35012325
Autor:
Laura J. Corbin, Stephen J. White, Amy E. Taylor, Christopher M. Williams, Kurt Taylor, Marion T. van den Bosch, Jack E. Teasdale, Matthew Jones, Mark Bond, Matthew T. Harper, Louise Falk, Alix Groom, Georgina G.J. Hazell, Lavinia Paternoster, Marcus R. Munafò, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Stig E. Bojesen, Caroline Relton, Josine L. Min, George Davey Smith, Andrew D. Mumford, Alastair W. Poole, Nicholas J. Timpson
Publikováno v:
Corbin, L J, White, S J, Taylor, A E, Williams, C M, Taylor, K, Van Den Bosch, M T, Teasdale, J E, Jones, M, Bond, M, Harper, M T, Falk, L, Groom, A, Hazell, G G J, Paternoster, L, Munafò, M R, Nordestgaard, B G, Tybjærg-Hansen, A, Bojesen, S E, Relton, C, Min, J L, Davey Smith, G, Mumford, A D, Poole, A W & Timpson, N J 2022, ' Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function ', Circulation Research, vol. 130, no. 3, pp. 384-400 . https://doi.org/10.1161/CIRCRESAHA.121.318836
Corbin, L J, White, S J, Taylor, A E, Williams, C M, Taylor, K, Van Den Bosch, M T J, Teasdale, J E, Jones, M L, Bond, M, Harper, M T, Falk, L, Groom, A, Hazell, G G J, Paternoster, L, Munafo, M R, Nordestgaard, B G, Tybjaerg-Hansen, A, Bojesen, S E, Relton, C L, Min, J L, Davey Smith, G, Mumford, A D, Poole, A W & Timpson, N J 2022, ' Epigenetic regulation of F2RL3 associates with myocardial infarction and platelet function ', Circulation Research, vol. 130, no. 3, pp. 384-400 . https://doi.org/10.1161/CIRCRESAHA.121.318836
Corbin, L J, White, S J, Taylor, A E, Williams, C M, Taylor, K, Van Den Bosch, M T J, Teasdale, J E, Jones, M L, Bond, M, Harper, M T, Falk, L, Groom, A, Hazell, G G J, Paternoster, L, Munafo, M R, Nordestgaard, B G, Tybjaerg-Hansen, A, Bojesen, S E, Relton, C L, Min, J L, Davey Smith, G, Mumford, A D, Poole, A W & Timpson, N J 2022, ' Epigenetic regulation of F2RL3 associates with myocardial infarction and platelet function ', Circulation Research, vol. 130, no. 3, pp. 384-400 . https://doi.org/10.1161/CIRCRESAHA.121.318836
Background: DNA hypomethylation at the F2RL3 (F2R like thrombin or trypsin receptor 3) locus has been associated with both smoking and atherosclerotic cardiovascular disease; whether these smoking-related associations form a pathway to disease is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473fb21bcf65ec3e1e8f70d3954772e
https://curis.ku.dk/portal/da/publications/epigenetic-regulation-of-f2rl3-associates-with-myocardial-infarction-and-platelet-function(9edd7f9a-ae4c-4c1a-8e3e-eda1d3fad1da).html
https://curis.ku.dk/portal/da/publications/epigenetic-regulation-of-f2rl3-associates-with-myocardial-infarction-and-platelet-function(9edd7f9a-ae4c-4c1a-8e3e-eda1d3fad1da).html
Autor:
Glenn Ferris, Amir Keshmiri, Alex Langford-Smith, Hans Degens, Ping Wang, Martin Humphries, Jason L. Johnson, Yvonne Alexander, Stephen J. White, Thomas W Johnson, Michael McElroy, Frank J. H. Gijsen, Sandro Satta, Peter Libby, Georgina G J Hazell, Jack E. Teasdale, Ghislaine Gayan-Ramirez, Giampaolo Niccoli, Filippo Crea, Graciela B. Sala-Newby, Ajime Tom Tanjeko, Jef Serré, Yongcheol Kim, Andrew C. Newby
Publikováno v:
Acute Coronary Syndromes.
Introduction Endothelial erosion of atherosclerotic plaques and resulting thrombosis causes approximately 30% of acute coronary syndromes (ACS). Plaque erosion is most frequently observed in smokers, which induces endothelial dysfunction, partially t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3553a3e703a801777cba470d3a1772a
https://doi.org/10.1136/heartjnl-2019-bcs.140
https://doi.org/10.1136/heartjnl-2019-bcs.140
Autor:
Martin J. Humphries, Amir Keshmiri, Yvonne Alexander, Ping Wang, Thomas W Johnson, Alex Langford-Smith, Peter Libby, Jason L. Johnson, Georgina G J Hazell, Sandro Satta, Jef Serré, Yongcheol Kim, Andrew C. Newby, Jack E. Teasdale, Ghislaine Gayan-Ramirez, Michael McElroy, Stephen J. White, Glenn Ferris, G. Sala Newby, Hans Degens, F.J.H. Gijsen, Ajime Tom Tanjeko, Giampaolo Niccoli, Filippo Crea
Endothelial erosion of atherosclerotic plaques and resulting thrombosis causes approximately 30% of acute coronary syndromes (ACS). As changes in the haemodynamic environment strongly influence endothelial function and contribute to plaque developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce508baf86bca28d2644acbfc789652
https://doi.org/10.1101/537852
https://doi.org/10.1101/537852
Publikováno v:
Teasdale, J E, Newby, A C, Timpson, N J, Munafò, M R & White, S J 2016, ' Cigarette smoke but not electronic cigarette aerosol activates a stress response in human coronary artery endothelial cells in culture ', Drug and Alcohol Dependence, vol. 163, pp. 256-260 . https://doi.org/10.1016/j.drugalcdep.2016.04.020
Drug and Alcohol Dependence
Drug and Alcohol Dependence
Highlights • Human coronary artery endothelial cells show a biological response to cigarette smoke. • This response was not seen following exposure to e-cigarette aerosol. • Using e-cigarettes instead of cigarettes may reduce immediate cardiova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdea4bd0495bb82a2f299404e07b8b6
https://doi.org/10.1016/j.drugalcdep.2016.04.020
https://doi.org/10.1016/j.drugalcdep.2016.04.020
Autor:
Alastair W. Poole, Nicholas J. Timpson, Kurt Taylor, Marion T.J. van den Bosch, Andrew D Mumford, Børge G. Nordestgaard, Amy E Taylor, Alix Groom, Christopher Williams, Lavinia Paternoster, Stig E. Bojesen, Jack E. Teasdale, Stephen J. White, Matthew Jones, Georgina G J Hazell, Anne Tybjærg-Hansen, Louise Falk, Laura J Corbin, Marcus R. Munafò, Caroline L Relton, Josine L. Min, George Davey Smith, Matthew T. Harper, Mark Bond
Protease-activated receptor 4 (PAR4) is a potent thrombin receptor. Epigenetic control of theF2RL3locus (which encodes for PAR4) via DNA methylation is associated with both smoking and cardiovascular disease. We examined the association between DNA h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e2cbf6dd5c1e49b88c3df8aab21f87
https://doi.org/10.1101/473728
https://doi.org/10.1101/473728
Autor:
Stephen J. White, Tom Johnson, Georgina Hazell, Jason Johnson, Graciela Sala-Newby, Yvonne Alexander, Sandro Satta, Andrew Newby, Jack E. Teasdale
Publikováno v:
Basic Science.
Endothelial erosion of plaques is the underlying mechanism of approximately 30% of heart attacks. It describes a pathology where endothelial detachment from an intact fibrous cap (normally over a highly-stenotic plaque) precipitates thrombosis, trigg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41bf848542b90e18cf7b3b0342740323
https://doi.org/10.1136/heartjnl-2018-bcs.131
https://doi.org/10.1136/heartjnl-2018-bcs.131
Autor:
Andrew C. Newby, Jack E. Teasdale, Stephen J. White, Yvonne Alexander, A. Peachey, Georgina Hazell, T. McKay, Graciela B. Sala-Newby, Jason L. Johnson, Sandro Satta
Publikováno v:
European Heart Journal. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d465d3bec0b6e56820a212705da0e01
https://doi.org/10.1093/eurheartj/ehx504.p3487
https://doi.org/10.1093/eurheartj/ehx504.p3487
Autor:
Jack E, Teasdale, Georgina G J, Hazell, Alasdair M G, Peachey, Graciela B, Sala-Newby, Charles C T, Hindmarch, Tristan R, McKay, Mark, Bond, Andrew C, Newby, Stephen J, White
Publikováno v:
Scientific Reports
Endothelial dysfunction caused by the combined action of disturbed flow, inflammatory mediators and oxidants derived from cigarette smoke is known to promote coronary atherosclerosis and increase the likelihood of myocardial infarctions and strokes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a55a3861636ed16a1b1d87a374465adc
https://pubmed.ncbi.nlm.nih.gov/28059114
https://pubmed.ncbi.nlm.nih.gov/28059114
Autor:
Georgina G J, Hazell, Alasdair M G, Peachey, Jack E, Teasdale, Graciela B, Sala-Newby, Gianni D, Angelini, Andrew C, Newby, Stephen J, White
Publikováno v:
Scientific Reports
Raised endothelial shear stress is protective against atherosclerosis but such protection may be lost at sites of inflammation. We found that four splice variants of the peptidase inhibitor 16 (PI16) mRNA are among the most highly shear stress regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37428234914a3e485e66540877188e2c
https://pubmed.ncbi.nlm.nih.gov/27996045
https://pubmed.ncbi.nlm.nih.gov/27996045