Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jack D. Chan"'
Autor:
Imran G. House, Emily B. Derrick, Kevin Sek, Amanda X.Y. Chen, Jasmine Li, Junyun Lai, Kirsten L. Todd, Isabelle Munoz, Jessica Michie, Cheok Weng Chan, Yu-Kuan Huang, Jack D. Chan, Emma V. Petley, Junming Tong, DatMinh Nguyen, Sven Engel, Peter Savas, Simon J. Hogg, Stephin J. Vervoort, Conor J. Kearney, Marian L. Burr, Enid Y.N. Lam, Omer Gilan, Sammy Bedoui, Ricky W. Johnstone, Mark A. Dawson, Sherene Loi, Phillip K. Darcy, Paul A. Beavis
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113793- (2024)
Externí odkaz:
https://doaj.org/article/3bc9e9ff1e6348e1add4deb56de520ff
Autor:
Imran G. House, Emily B. Derrick, Kevin Sek, Amanda X.Y. Chen, Jasmine Li, Junyun Lai, Kirsten L. Todd, Isabelle Munoz, Jessica Michie, Cheok Weng Chan, Yu-Kuan Huang, Jack D. Chan, Emma V. Petley, Junming Tong, DatMinh Nguyen, Sven Engel, Peter Savas, Simon J. Hogg, Stephin J. Vervoort, Conor J. Kearney, Marian L. Burr, Enid Y.N. Lam, Omer Gilan, Sammy Bedoui, Ricky W. Johnstone, Mark A. Dawson, Sherene Loi, Phillip K. Darcy, Paul A. Beavis
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113014- (2023)
Summary: CXCL9 expression is a strong predictor of response to immune checkpoint blockade therapy. Accordingly, we sought to develop therapeutic strategies to enhance the expression of CXCL9 and augment antitumor immunity. To perform whole-genome CRI
Externí odkaz:
https://doaj.org/article/36f8c10bf54b436e8b3737f736a4464b
Autor:
Emma V. Petley, Hui-Fern Koay, Melissa A. Henderson, Kevin Sek, Kirsten L. Todd, Simon P. Keam, Junyun Lai, Imran G. House, Jasmine Li, Magnus Zethoven, Amanda X. Y. Chen, Amanda J. Oliver, Jessica Michie, Andrew J. Freeman, Lauren Giuffrida, Jack D. Chan, Angela Pizzolla, Jeffrey Y. W. Mak, Timothy R. McCulloch, Fernando Souza-Fonseca-Guimaraes, Conor J. Kearney, Rosemary Millen, Robert G. Ramsay, Nicholas D. Huntington, James McCluskey, Jane Oliaro, David P. Fairlie, Paul J. Neeson, Dale I. Godfrey, Paul A. Beavis, Phillip K. Darcy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Mucosal-associated invariant T (MAIT) cells facilitate anti-microbial responses, but their functions in cancer protection is unclear. Here the authors show that activated MAIT cells induce an IFN-γ transcriptome in natural killer (NK) cells and enha
Externí odkaz:
https://doaj.org/article/01f893fc7b8b403cadf95ab8ec274a3e
Autor:
Aesha I. Ali, Amanda J. Oliver, Tinaz Samiei, Jack D. Chan, Michael H. Kershaw, Clare Y. Slaney
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Conventional treatments for pancreatic cancer are largely ineffective, and the prognosis for the vast majority of patients is poor. Clearly, new treatment options are desperately needed. Immunotherapy offers hope for the development of treatments for
Externí odkaz:
https://doaj.org/article/51e0a4cffdf94123945068b69d0132df
Autor:
Jack D Chan, Bianca vonScheidt, Bijun Zeng, Amanda J Oliver, Ashleigh S Davey, Aesha I Ali, Ranjeny Thomas, Joseph A Trapani, Phillip K Darcy, Michael H Kershaw, Riccardo Dolcetti, Clare Y Slaney
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Objectives Adoptive transfer of chimeric antigen receptor (CAR)‐modified T cells is a form of cancer immunotherapy that has achieved remarkable efficacy in patients with some haematological cancers. However, challenges remain in CAR T‐ce
Externí odkaz:
https://doaj.org/article/fcf8f427b57d41fd96ae5a6361cd0f8b
Autor:
Amanda J Oliver, Ashleigh S Davey, Simon P Keam, Sherly Mardiana, Jack D Chan, Bianca vonScheidt, Paul A Beavis, Imran G House, Jonas RM Van Audernaerde, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 11, Pp n/a-n/a (2019)
Abstract Objectives Investigation of variable response rates to cancer immunotherapies has exposed the immunosuppressive tumor microenvironment (TME) as a limiting factor of therapeutic efficacy. A determinant of TME composition is the tumor location
Externí odkaz:
https://doaj.org/article/84748edd17204404b2b19d4bc17f0392
Autor:
Clare Y. Slaney, Michael H. Kershaw, Phillip K. Darcy, Ricky W. Johnstone, Belinda Lee, Yuchen Bai, Xin Du, Jack D. Chan, Amanda J. Oliver, Jian Kang, Daniela G.M. Tantalo, Aaron J. Harrison, Pilar M. Dominguez, Bianca von Scheidt, Minyu Wang, Aesha I. Ali
Supplementary Figure 3. Pano induced pancreatic tumor cell apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34389ace6e4270528428771aeee8c0d2
https://doi.org/10.1158/1078-0432.22481435.v1
https://doi.org/10.1158/1078-0432.22481435.v1
Autor:
Clare Y. Slaney, Michael H. Kershaw, Phillip K. Darcy, Ricky W. Johnstone, Belinda Lee, Yuchen Bai, Xin Du, Jack D. Chan, Amanda J. Oliver, Jian Kang, Daniela G.M. Tantalo, Aaron J. Harrison, Pilar M. Dominguez, Bianca von Scheidt, Minyu Wang, Aesha I. Ali
Supplementary Figure 2. Pancreatic cells are resistant to VV-gp100 oncolysis but sensitive to CAR T cell-mediated cytotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c9d72027703a914aafcf22cecdd8a7
https://doi.org/10.1158/1078-0432.22481438
https://doi.org/10.1158/1078-0432.22481438
Autor:
Clare Y. Slaney, Michael H. Kershaw, Phillip K. Darcy, Ricky W. Johnstone, Belinda Lee, Yuchen Bai, Xin Du, Jack D. Chan, Amanda J. Oliver, Jian Kang, Daniela G.M. Tantalo, Aaron J. Harrison, Pilar M. Dominguez, Bianca von Scheidt, Minyu Wang, Aesha I. Ali
Supplementary Figure 4. Pano did not enhance the cytotoxicity of CARaMEL cells nor oncolysis of VV-gp100.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee265cad79f9b4e9fa3df5a79596bbb
https://doi.org/10.1158/1078-0432.22481429
https://doi.org/10.1158/1078-0432.22481429
Autor:
Clare Y. Slaney, Michael H. Kershaw, Phillip K. Darcy, Ricky W. Johnstone, Belinda Lee, Yuchen Bai, Xin Du, Jack D. Chan, Amanda J. Oliver, Jian Kang, Daniela G.M. Tantalo, Aaron J. Harrison, Pilar M. Dominguez, Bianca von Scheidt, Minyu Wang, Aesha I. Ali
Supplementary Figure 1. Panc02-Her2, KPC-Her2 and 24JK-Her2 cells express comparable levels of Her2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32234af432f472a714e764329e3cfe8e
https://doi.org/10.1158/1078-0432.22481441.v1
https://doi.org/10.1158/1078-0432.22481441.v1