Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jack D. Anderson"'
Autor:
Roger J. Bontems, Howard B. Cottam, Hassan A. Alaghamandan, Roland K. Robins, Jack D. Anderson, Donald F. Smee, W. B. Jolley, B. S. Sharma, A. Jin
Publikováno v:
ChemInform. 22
Several guanosine analogues were synthesized in the pyrazolo[3,4-d]pyrimidine ring system with various substituents at the 3-position. The new analogues prepared here include the CH3 (2-amino-3-methyl-1-beta-D-ribofuranosylpyrazolo[3,4-d]pyrimidin-4
Autor:
Donald F. Smee, Ganesh D. Kini, Yogesh S. Sanghvi, Ganapathi R. Revankar, Howard B. Cottam, Jack D. Anderson, Roland K. Robins, Arthur F. Lewis
Publikováno v:
ChemInform. 23
Several sugar-modified nucleoside derivatives of the purine analogue 5-amino-3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidine-2,7-dione (1) were synthesized. Phosphorylation of 1 using POCl3 resulted in 5'-monophosphate 2, which was subsequently conve
Autor:
Jack D. Anderson, Arthur F. Lewis, Yogesh S. Sanghvi, Howard B. Cottam, Ganesh D. Kini, Roland K. Robins, Ganapathi R. Revankar, Donald F. Smee
Publikováno v:
Journal of Medicinal Chemistry. 34:3006-3010
Several sugar-modified nucleoside derivatives of the purine analogue 5-amino-3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidine-2,7-dione (1) were synthesized. Phosphorylation of 1 using POCl3 resulted in 5'-monophosphate 2, which was subsequently conve
Autor:
L. Dee Nord, Steven B. Larson, Jack D. Anderson, G. R. Revankar, Roland K. Robins, Howard B. Cottam
Publikováno v:
Journal of Heterocyclic Chemistry. 27:439-453
Synthesis of the pyrazolo[3,4-d]pyrimidin-3-one congeners of guanosine, adenosine and inosine is described. Glycosylation of 3-methoxy-6-methylthio-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (13) with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose (16) in
Autor:
Roland K. Robins, Howard B. Cottam, Roger J. Bontems, W. B. Jolley, Hassan A. Alaghamandan, B. S. Sharma, A. Jin, Jack D. Anderson, Donald F. Smee
Publikováno v:
Journal of medicinal chemistry. 33(8)
Several guanosine analogues were synthesized in the pyrazolo[3,4-d]pyrimidine ring system with various substituents at the 3-position. The new analogues prepared here include the CH3 (2-amino-3-methyl-1-beta-D-ribofuranosylpyrazolo[3,4-d]pyrimidin-4
Autor:
K Nagahara, Ganesh D. Kini, Brahma S. Sharma, Roland K. Robins, Jack D. Anderson, Steven B. Larson, N. K. Dalley, Donald F. Smee, Weldon B. Jolley, Ai Jin
Publikováno v:
Journal of medicinal chemistry. 33(1)
Novel analogues of the naturally occurring purine nucleosides were synthesized in the thiazolo[4,5-d]pyrimidine ring system to determine the immunomodulatory effects of insertion of a sulfur atom in place of nitrogen at position 7 of the purine ring.
Publikováno v:
Journal of Speech and Hearing Disorders. 45:195-199
The Carrow (1973) Test for Auditory Comprehension of Language (TACL) is used frequently as part of a test battery to assess the language skills of mentally retarded children. This study determined its reliability with this population using a test-re-
Publikováno v:
Journal of Heterocyclic Chemistry. 23:1869-1878
Several 3-alkoxysubstituted pyrazolo[3,4-d]pyrimidine ribonucleosides structurally related to adenosine, inosine and guanosine have been prepared by the direct glycosylation of preformed aglycon precursor containing a 3-alkoxy substituent. Ring closu
Publikováno v:
Nucleosides and Nucleotides. 6:853-863
The synthesis of pyrazolo[3,4-d]pyrimidine ribonucleoside 3′, 5′-cyclic phosphates related to cAMP, cIMP and cGMP has been achieved for the first time. Phosphorylation of 4-amino-6-methylthio-1-β-D-ribo-furanosylpyrazolo[3,4-d]pyrimidine (1) wit
Autor:
Steven S. Matsumoto, Howard B. Cottam, Stewart Geary, Jack D. Anderson, Roger J. Bontems, Steven B. Larson, Donald F. Smee, Roland K. Robins
Publikováno v:
Nucleosides and Nucleotides. 8:1201-1216
Tubercidin (7-deazaadenosine, 1a) and several 6-chlorotuber-cidin derivatives were synthesized including 4-amino-6-chloro-7-β-D-ribofuranosylpyrrolo[2,3-d]pyrimidine-3′,5′-cycyclic phosphate 9. Isolation of a side product found in the glycosylat