Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jack D Newman"'
Autor:
Hiroko Tsuruta, Christopher J Paddon, Diana Eng, Jacob R Lenihan, Tizita Horning, Larry C Anthony, Rika Regentin, Jay D Keasling, Neil S Renninger, Jack D Newman
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4489 (2009)
BackgroundArtemisinin derivatives are the key active ingredients in Artemisinin combination therapies (ACTs), the most effective therapies available for treatment of malaria. Because the raw material is extracted from plants with long growing seasons
Externí odkaz:
https://doaj.org/article/29329a6165654224a54f2846107a793c
Autor:
Jessica M, Walter, Max G, Schubert, Stephanie H, Kung, Kristy, Hawkins, Darren M, Platt, Aaron D, Hernday, Tina, Mahatdejkul-Meadows, Wayne, Szeto, Sunil S, Chandran, Jack D, Newman, Andrew A, Horwitz
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2049
CRISPR-Cas has proven to be a powerful tool for precision genetic engineering in a variety of difficult genetic systems. In the highly tractable yeast S. cerevisiae, CRISPR-Cas can be used to conduct multiple engineering steps in parallel, allowing f
Autor:
Eugene Antipov, Lishan Zhao, Peter Jackson, Pinghua Liu, Sheela Muley, Jack D. Newman, Kevin L. Dietzel, Jeremy LaBarge, James Kirby, Gale Wichmann, Jay D. Keasling, Shayin S. Gottlieb, Sara P. Gaucher, Nathan A. Moss, Rossana Chan, Edward E. K. Baidoo, Kristy Michelle Hawkins, Tina Mahatdejkul
Publikováno v:
Kirby, J; Dietzel, KL; Wichmann, G; Chan, R; Antipov, E; Moss, N; et al.(2016). Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae. Metabolic Engineering, 38, 494-503. doi: 10.1016/j.ymben.2016.10.017. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/38t56316
© 2016 International Metabolic Engineering Society Isoprenoids are used in many commercial applications and much work has gone into engineering microbial hosts for their production. Isoprenoids are produced either from acetyl-CoA via the mevalonate
Autor:
Kristy Michelle Hawkins, Darren Platt, Max G. Schubert, Sunil S. Chandran, Andrew A. Horwitz, Jack D. Newman, Tina Mahatdejkul-Meadows, Jessica M. Walter, Stephanie H. Kung, Aaron D. Hernday, Wayne Szeto
Publikováno v:
Methods in Molecular Biology ISBN: 9781493997350
CRISPR-Cas has proven to be a powerful tool for precision genetic engineering in a variety of difficult genetic systems. In the highly tractable yeast S. cerevisiae, CRISPR-Cas can be used to conduct multiple engineering steps in parallel, allowing f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad30205bac9a685c020b058739f269cf
https://doi.org/10.1007/978-1-4939-9736-7_3
https://doi.org/10.1007/978-1-4939-9736-7_3
Autor:
Aaron D. Hernday, Sunil S. Chandran, Stephanie H. Kung, Wayne Szeto, Jessica M. Walter, Max G. Schubert, Tina Mahatdejkul-Meadows, Kristy Michelle Hawkins, Darren Platt, Jack D. Newman, Andrew A. Horwitz
Publikováno v:
Horwitz, AA; Walter, JM; Schubert, MG; Kung, SH; Hawkins, K; Platt, DM; et al.(2015). Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas. Cell Systems, 1(1), 88-96. doi: 10.1016/j.cels.2015.02.001. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/01d6s8m1
Cell systems, vol 1, iss 1
Cell systems, vol 1, iss 1
© 2015 The Authors. Summary CRISPR-Cas genome engineering in yeast has relied on preparation of complex expression plasmids for multiplexed gene knockouts and point mutations. Here we show that co-transformation of a single linearized plasmid with m
Autor:
Adriana Costero-Saint Denis, Stephanie L. James, John Bauer, William McGinnis, Chris A. Wozniak, Anthony M. Shelton, Alan Pearson, Brinda Dass, Peter C. Ellsworth, Sarah R. Carter, Mark S. Hoddle, Clark C. Gibson, Robert Friedman, Michael W. Kalichman, Bruce A. Hay, Jack D. Newman, Joseph M. Vinetz, Lyric A. Jorgenson, Cinnamon S. Bloss, Zach N. Adelman, Ethan Bier, Jennifer Weisman, Brenda Wong, Larisa Rudenko, Mary Devereaux, Hector Quemada, John M. Marshall, Anthony A. James, Craig Callender, Valentino M. Gantz, Omar S. Akbari, Peter F. Cowhey, Jason A. Delborne
Publikováno v:
Nature biotechnology, vol 35, iss 8
Approximately two years ago, two of us (E.B. and V.G.) demonstrated the first experimental application of CRISPR–Cas9 to 'drive' a desired trait throughout a population of fruit flies. In November 2015, this same team at the University of Californi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0de1446659929109871ef408b78a872
https://escholarship.org/uc/item/9qc3p2nq
https://escholarship.org/uc/item/9qc3p2nq
Autor:
Kirsten R. Benjamin, D. Dengrove, T. Treynor, Hanxiao Jiang, Darwin W. Reed, Karl Fisher, Douglas J. Pitera, S. Secrest, Kenneth W. Ellens, Patrick J. Westfall, M. Yu, Rika Regentin, T. Iqbal, A. Main, H. Tsuruta, Derek McPhee, Tizita Horning, R. Vazquez, S. Bajad, Ronald Henry, G. Dang, Keat H. Teoh, Jefferson C. Lievense, J. Galazzo, Scott Fickes, L. Kizer, Don Diola, Anna Tai, K. K. Reiling, B. Lieu, Patrick S. Covello, Lars F. Westblade, G. Dorin, Sara P. Gaucher, M. Fleck, Jacob R. Lenihan, M. Hepp, Michael D. Leavell, N. S. Renninger, Lishan Zhao, D. Melis, Diana Eng, Lan Xu, Jay D. Keasling, Christopher J. Paddon, Nathan A. Moss, T. Geistlinger, Jack D. Newman, Devin R Polichuk, Yansheng Zhang
Publikováno v:
Nature. 496:528-532
Saccharomyces cerevisiae is engineered to produce high concentrations of artemisinic acid, a precursor of the artemisinin used in combination therapies for malaria treatment; an efficient and practical chemical process to convert artemisinic acid to
Publikováno v:
Nature Biotechnology. 21:796-802
Isoprenoids are the most numerous and structurally diverse family of natural products. Terpenoids, a class of isoprenoids often isolated from plants, are used as commercial flavor and fragrance compounds and antimalarial or anticancer drugs. Because
Autor:
Sunil S. Chandran, Kedar G. Patel, Stefan de Kok, Jack D. Newman, Zach Serber, Leslie H. Stanton, Darren Platt, Victor Holmes, Maxime Durot, Todd Slaby, Jed Dean, Elaine B. Shapland
Publikováno v:
ACS synthetic biology. 3(2)
Assembly of DNA parts into DNA constructs is a foundational technology in the emerging field of synthetic biology. An efficient DNA assembly method is particularly important for high-throughput, automated DNA assembly in biofabrication facilities and
Publikováno v:
Journal of Molecular Biology. 313:485-499
The Rhodobacter sphaeroides extra cytoplasmic function sigma factor, sigma(E), directs transcription of promoters for the cycA gene (cycA P3) and the rpoEchrR operon (rpoE P1). These genes encode the periplasmic electron carrier cytochrome c(2) and s