Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jack Cheung"'
Autor:
Sarah Anne Bird, Marco Licciardello, Yakinthi Chrisochoidou, James Smith, Amy Barber, Jack Cheung, Yura Grabovska, Shannon Martin, Fernando Sialana, Harvey Che, Habib Bouguenina, Benjamin Bellenie, Brian Walker, Paul Clarke, Charlotte Pawlyn
Publikováno v:
Cancer Research. 83:3879-3879
Immunomodulatory agents (IMiDs) and cereblon E3 ligase modulators (CELMoDs) are a cornerstone of Multiple Myeloma (MM) treatment. They bind to the cereblon (CRBN) component of the CRL4 E3 ubiquitin ligase complex and designate a new set of substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df84d49b190f9d8cc7b3756199fc8dc3
https://doi.org/10.1158/1538-7445.am2023-3879
https://doi.org/10.1158/1538-7445.am2023-3879
Publikováno v:
2016 15th International Conference on Optical Communications and Networks (ICOCN).
We construct a high gain high output power 1310 nm hybrid fiber amplifier, which can be use in telecommunication. It is a compact design combining a semiconductor optical amplifier (SOA) and a discrete Raman amplifier. It is hard to construct such am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23db1d607b94a3b1f9a2ce2b80f12a4
https://doi.org/10.1109/icocn.2016.7875699
https://doi.org/10.1109/icocn.2016.7875699
Publikováno v:
2016 15th International Conference on Optical Communications and Networks (ICOCN).
We demonstrate a 2 µm passive mode-locked fiber laser. A single-wall carbon nanotube (SWCNT) is used as saturable absorber. Thulium-doped fiber (TDF) is used as the gain medium. The output wavelength is grating stabilized to 1998.85 nm by a high ref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caad984b80f8156491145e5e0fe76c07
https://doi.org/10.1109/icocn.2016.7875669
https://doi.org/10.1109/icocn.2016.7875669
Publikováno v:
2016 15th International Conference on Optical Communications and Networks (ICOCN).
Generation of super-continuum by using 5 m ultra-high NA silica optical fiber (UHNA3) with core diameter 1.8 µm and mode-field diameter (MFD) ∼2.6µm is compared with Photonic Crystal Fiber (PCF). A 1064 nm gained switched pico-second semiconducto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0812619611c2dafa098b191195a4e2
https://doi.org/10.1109/icocn.2016.7875875
https://doi.org/10.1109/icocn.2016.7875875
Publikováno v:
Photonics and Fiber Technology 2016 (ACOFT, BGPP, NP).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451a328abfd37181c7a4be65986212fc
https://doi.org/10.1364/acoft.2016.jm6a.3
https://doi.org/10.1364/acoft.2016.jm6a.3
Autor:
Swen Hoelder, Richard Bayliss, Andrew M. Fry, Mark W. Richards, Joelle M. Y. Blot, Jack Cheung, Laura O'Regan, Corine Mas-Droux
Publikováno v:
Molecular Cell
Summary Mitosis is controlled by multiple protein kinases, many of which are abnormally expressed in human cancers. Nek2, Nek6, Nek7, and Nek9 are NIMA-related kinases essential for proper mitotic progression. We determined the atomic structure of Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f51e6a4f62a082ccbb0da651b69033
Autor:
Ping Kong Alexander Wai, K. S. Tsang, Li Jin, Victor Ho, Sai T. Chu, Jack Cheung, Alessia Pasquazi, Ray Man
Publikováno v:
Scopus-Elsevier
We demonstrated a 1.81 μm mode-locked figure-eight laser using an integrated 11-th order microring resonator. Mode-locked train centered at 1.81 μm with repetition rate of 9.09 MHz is achieved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d5f35497a24746781870f5b7e44fae
https://doi.org/10.1364/acpc.2015.am3b.6
https://doi.org/10.1364/acpc.2015.am3b.6
Autor:
Spiros Linardopoulos, Rosemary Burke, Grace Mak, Julian Blagg, Craig McAndrew, Jack Cheung, Paul Workman, Kathy Boxall, Jessica Schmitt, Isaac M. Westwood, Sébastien Naud, Amy Wood, Swen Hoelder, Amir Faisal, Rob L. M. van Montfort, Mark D. Gurden
Publikováno v:
Cancer Research. 75:5450-5450
Acquired resistance is the greatest challenge to the effectiveness of targeted anti-cancer therapies in the clinic. With several MPS1 inhibitors under pre-clinical development, we aimed to investigate how cancer cells will develop resistance against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbd4a15d1089c078bbe5c6ce5434b0b
https://doi.org/10.1158/1538-7445.am2015-5450
https://doi.org/10.1158/1538-7445.am2015-5450
Autor:
Jack Cheung, Sebastan Naud, Ross Baker, Peter Sheldrake, Paul Workman, Paolo Innocenti, Vassilios Bavetsias, Suzanne A. Eccles, Butrus Atrash, Rob vanMontfort, Jessica Schmitt, Swen Hoelder, Spiros Linardopoulos, Rosemary Burke, Julian Blagg, Grace Mak, Melanie Valenti, Hannah Woodward, Isaac M. Westwood, Mark D. Gurden, Craig McAndrew, Florence I. Raynaud, Amir Faisal, Angela Hayes, Martin G. Rowlands
Publikováno v:
Cancer Research. 73:3242-3242
The main role of the cell cycle is to enable error-free DNA replication, chromosome segregation and cytokinesis. Surveillance mechanisms, the so-called checkpoint pathways, monitor passage through mitosis at several stages. One of the best characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e096a3e74ba78b4de6c8aeacc5419aca
https://doi.org/10.1158/1538-7445.am2013-3242
https://doi.org/10.1158/1538-7445.am2013-3242