Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jack C.-C. Hsu"'
Autor:
Eric H.-L. Chen, Tony T.-Y. Lu, Jack C.-C. Hsu, Yufeng Jane Tseng, T.-S. Lim, Rita P.-Y. Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract In order to directly observe the refolding kinetics from a partially misfolded state to a native state in the bottom of the protein-folding funnel, we used a “caging” strategy to trap the β-sheet structure of ubiquitin in a misfolded co
Externí odkaz:
https://doaj.org/article/7e49e2049803490d8d197737a1428dac
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance To establish infection, pathogenic viruses have to overcome the type I interferon (IFN-I) antiviral response. A previous study demonstrated that the SARS-CoV-2 NSP14 is able to inhibit IFN-I responses. In this study, we report that SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055e3cff7e15b4931002ad94a54b4af2
http://europepmc.org/articles/PMC8214666
http://europepmc.org/articles/PMC8214666
Publikováno v:
Current Research in Virological Science, Vol 2, Iss, Pp 100012-(2021)
The innate immune response serves as a robust first line of defense against pathogens, protecting the host from infectious organisms in a rapid and antigen-independent manner. Viral infection activates the type I interferon (IFN-I) response, leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5818e3072695cd5b318fa703ebaf7bb7
http://www.sciencedirect.com/science/article/pii/S2666478X21000064
http://www.sciencedirect.com/science/article/pii/S2666478X21000064
Autor:
Maudry Laurent-Rolle, Nathan D. Grubaugh, Laura Manuelidis, Jack C.-C. Hsu, Pagano N, Chantal B.F. Vogels
Many viruses infect circulating mononuclear cells thereby facilitating infection of diverse organs. Blood monocytes (PBMC) are being intensively studied as immunologic and pathologic responders to the new SARS-CoV-2 virus (CoV19) but direct evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5baef6eb8c37636c7f9c06d6bad999cd
https://doi.org/10.1101/2020.12.16.423113
https://doi.org/10.1101/2020.12.16.423113
Publikováno v:
Infection Control & Hospital Epidemiology
Infection Control and Hospital Epidemiology
Infection Control and Hospital Epidemiology
The incubation period of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rarely >14 days. We report a patient with hypogammaglobulinemia who developed coronavirus disease 2019 (COVID-19) with a confirmed incubation period of at least
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a1a021ae3227f5baaeb2284e438777
Publikováno v:
RNA. 24:688-703
Astrocyte elevated gene-1 (AEG-1), an oncogene whose overexpression promotes tumor cell proliferation, angiogenesis, invasion, and enhanced chemoresistance, is thought to function primarily as a scaffolding protein, regulating PI3K/Akt and Wnt/β-cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b3c705148094070699d3700dc8e143
https://doi.org/10.1261/rna.063313.117
https://doi.org/10.1261/rna.063313.117
Autor:
Jia Cui, Hongzhen Tang, Shuai Zhao, Tao Wang, Ruochen Zang, Haijing Deng, Triantafyllia R. Karakousi, Maria E. Kaczmarek, Tina Tianjiao Su, Ze Zhang, Jia Liu, Xufeng Chen, Michael S. Diamond, Zemin Zhang, Fei Tang, Sergei B. Koralov, Jun Wang, Shumin Jin, Kenneth A. Stapleford, Peter Cresswell, Qiang Zhou, Rita E. Chen, Alberto Herrera, Qi Xie, Stephen T. Yeung, Xianwen Ren, Jianzhu Ma, Marianna Teplova, Jack C.-C. Hsu, Xiaojuan Ran, Ming Zhou, Zhilin Long, Peng Lin, Jianbo Dong, Leopoldo N. Segal, Qiao Lu, Maria Florencia Gomez Castro, Iannis Aifantis, Renhong Yan, Betty Huang, Jasper Du, Tenny Mudianto, Juhee Son, Broc T. McCune, Payal Damani-Yokota, Maudry Laurent-Rolle, Yue Liu, James Zhu, Kamal M. Khanna, Siyuan Ding
Publikováno v:
Immunity
Despite mounting evidence for SARS-CoV-2 engagement with immune cells, most express little, if any, of the canonical receptor of SARS-CoV-2, ACE2. Here, using a myeloid-cell receptor-focused ectopic expression screen, we identified several C-type lec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1811fe56a4203d28a6e4f7f1ea7946b9
https://doi.org/10.1016/j.immuni.2021.05.006
https://doi.org/10.1016/j.immuni.2021.05.006
Autor:
Rita P.-Y. Chen, Eric H.-L. Chen, Tsong-Shin Lim, Jack C.-C. Hsu, Tony Tsung-Yu Lu, Yufeng J. Tseng
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
In order to directly observe the refolding kinetics from a partially misfolded state to a native state in the bottom of the protein-folding funnel, we used a “caging” strategy to trap the β-sheet structure of ubiquitin in a misfolded conformatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d096579a41583dd8755a8552003fcb0
https://doi.org/10.1038/s41598-017-08385-0
https://doi.org/10.1038/s41598-017-08385-0
Autor:
Qiang Chen, Christopher V. Nicchitta, Arthur Moseley, Sujatha Jagannathan, Will J. Thompson, Jack C.-C. Hsu, David W. Reid
Publikováno v:
Journal of Biological Chemistry. 289:25907-25924
Signal sequence-encoding mRNAs undergo translation-dependent localization to the endoplasmic reticulum (ER) and at the ER are anchored via translation on Sec61-bound ribosomes. Recent investigations into the composition and membrane association chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdabc67d5b687dc43a80fbf1e762290
https://doi.org/10.1074/jbc.m114.580688
https://doi.org/10.1074/jbc.m114.580688
Autor:
Chao-Ping Hsu, Frederick Y. Luh, Eric H.-L. Chen, Jack C.-C. Hsu, Rita P.-Y. Chen, Tsong-Shin Lim, Robert C. Snoeberger
Publikováno v:
The Journal of Physical Chemistry B. 117:3459-3468
In this work, we found that, during storage or after UV irradiation, ThT is demethylated or oxidized, forming three derivatives. These three derivatives were purified by high performance liquid chromatography and characterized by mass and nuclear mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5c8bbde3a9056e60112e8d35db2054
https://doi.org/10.1021/jp309331u
https://doi.org/10.1021/jp309331u