Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jack C. Hirst"'
Autor:
Anna Sims, Laura Burgess Tornaletti, Seema Jasim, Chiara Pirillo, Ryan Devlin, Jack C. Hirst, Colin Loney, Joanna Wojtus, Elizabeth Sloan, Luke Thorley, Chris Boutell, Edward Roberts, Edward Hutchinson
Publikováno v:
PLoS Biology, Vol 21, Iss 2 (2023)
Interactions between viruses during coinfections can influence viral fitness and population diversity, as seen in the generation of reassortant pandemic influenza A virus (IAV) strains. However, opportunities for interactions between closely related
Externí odkaz:
https://doaj.org/article/c46db530b8444fd5ab52213b9133be20
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Transcriptionally silent HIV proviruses form the major obstacle to eradicating HIV. Many studies of HIV latency have focused on the cellular mechanisms that maintain silencing of proviral DNA. Here we show that viral sequence variation affec
Externí odkaz:
https://doaj.org/article/5ec59ece3af14869b31e20e379fa66bf
Autor:
Edward C. Hutchinson, Jack C. Hirst
Publikováno v:
The Journal of general virology. 102(8)
Clinical isolates of influenza virus produce pleiomorphic virions, ranging from small spheres to elongated filaments. The filaments are seemingly adaptive in natural infections, but their basic functional properties are poorly understood and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141408110810e0349ec094d036c57b87
https://pubmed.ncbi.nlm.nih.gov/31553305
https://pubmed.ncbi.nlm.nih.gov/31553305
Autor:
Edward C. Hutchinson, Jack C. Hirst
Publikováno v:
The Journal of General Virology
Clinical isolates of influenza virus produce pleiomorphic virions, ranging from small spheres to elongated filaments. The filaments are seemingly adaptive in natural infections, but their basic functional properties are poorly understood and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75536cd1153dde11ecc647479c7ce19a
https://pubmed.ncbi.nlm.nih.gov/34406115
https://pubmed.ncbi.nlm.nih.gov/34406115
Publikováno v:
Access Microbiology. 1
Harry Smith Vacation Studentship Laboratory-adapted influenza viruses produce predominantly spherical virions. In contrast, clinical and veterinary isolates produce a mixture of virions of different sizes, from 0.1 µm spheres to filaments which can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cbffea8643a905b123ef2475e81e112
https://doi.org/10.1099/acmi.ac2019.po0122
https://doi.org/10.1099/acmi.ac2019.po0122
Publikováno v:
Access Microbiology. 1
Most laboratory strains of influenza virus produce near-spherical virions, but clinical isolates also produce extended filaments whose biophysical properties are understudied. Most functional studies of filamentous influenza viruses do not include da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794d2144bae4034e092cbd1d561aba07
https://doi.org/10.1099/acmi.ac2019.po0292
https://doi.org/10.1099/acmi.ac2019.po0292
Autor:
Patrycja Kozik, Edward C. Hutchinson, Maria Bottermann, Martin Berner McAdam, Jack C. Hirst, Greg Slodkowicz, Laurens M. van Tienen, Jessica Clark, Katie Higginson, Leo C. James, Keith Mayes, Stian Foss, Marina Vaysburd, James Cruickshank, Kevin O’Connell, Jan Terje Andersen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(41)
Adenovirus has enormous potential as a gene-therapy vector, but preexisting immunity limits its widespread application. What is responsible for this immune block is unclear because antibodies potently inhibit transgene expression without impeding gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae7af70ba19d975e6b08da07e83ed20
https://pubmed.ncbi.nlm.nih.gov/30232262
https://pubmed.ncbi.nlm.nih.gov/30232262