Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jack C. Bartley"'
Publikováno v:
Experimental Cell Research. 188:302-311
The membrane glycoprotein, PAS-O, is a major differentiation antigen on mammary epithelial cells and is located exclusively in the apical domain of the plasma membrane. We have used 734B cultured human mammary carcinoma cells as a model system to stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda1f571406eeef9c754b586e8c3a53b
https://doi.org/10.1016/0014-4827(90)90174-9
https://doi.org/10.1016/0014-4827(90)90174-9
Publikováno v:
Carcinogenesis. 12(9)
The metabolism of benzo[a]pyrene (B[a]P) and (-)-transbenzo[a]pyrene-7,8-dihydrodiol (B[a]P-diol) was compared in human mammary epithelial cells (HMEC) grown in serum-free medium, MCDB-170. Conversion of B[a]P-diol to the carcinogen (+)-benzo[a]pyren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb2d57d366173b8a1bc50e1384b65b4
https://pubmed.ncbi.nlm.nih.gov/1909936
https://pubmed.ncbi.nlm.nih.gov/1909936
Publikováno v:
Journal of Cellular Biochemistry. 18:135-148
We demonstrate in cell culture that mammary epithelial cells from normal human breast specimens metabolize benzo(a)pyrene (BaP) and form adducts with the bases of their DNA more readily and at lower concentrations of BaP than do fibroblasts from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3ed62fd138814248abb89bd4ed898c
https://doi.org/10.1002/jcb.1982.240180202
https://doi.org/10.1002/jcb.1982.240180202
Publikováno v:
Proceedings of the National Academy of Sciences. 78:6251-6255
Pure cultures of human breast epithelial cells and of fibroblastic cells in early passage provided the opportunity to ask whether either cell type had the capability for metabolizing chemical carcinogens and, if so, was the fate of the metabolic prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e2bed8b9dfd8e8887ff0397aeb11d3
https://doi.org/10.1073/pnas.78.10.6251
https://doi.org/10.1073/pnas.78.10.6251
Publikováno v:
Experimental Cell Research. 134:241-250
In the mammary gland of non-ruminant animals, glucose is utilized in a characteristic and unique way during lactation [11]. By measuring the incorporation of glucose carbon from [U- 14 C]glucose into intermediary metabolites and metabolic products in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cd905120f82c384d75d2223fbb7db7
https://doi.org/10.1016/0014-4827(81)90481-x
https://doi.org/10.1016/0014-4827(81)90481-x
Autor:
Jack C. Bartley
Publisher Summary This chapter explains lipid metabolism and its associated disorders. Lipids have special importance physiologically as the hydrophobic constituents of membranes and as the most concentrated source of energy of any of the major foods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::863eb0751151b58bdcb7e659cc39e9a2
https://doi.org/10.1016/b978-0-12-396350-5.50007-3
https://doi.org/10.1016/b978-0-12-396350-5.50007-3
Autor:
Jack C. Bartley, Duane F. Brobst, George H. Cardinet, Embert H. Coles, Charles E. Cornelius, W. Jean Dodds, Lars-Eric Edqvist, Delmar R. Finco, William E. Hornbuckle, Jiro J. Kaneko, John W. Kramer, Victor Perman, Mogens G. Simesen, George H. Stabenfeldt, Julia Stephens-Orvis, John B. Tasker, Bud C. Tennant, John S. Wilkinson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0742f57f8445952db4d6b1271910bac0
https://doi.org/10.1016/b978-0-12-396350-5.50004-8
https://doi.org/10.1016/b978-0-12-396350-5.50004-8
Autor:
Jack C. Bartley, Martha R. Stampfer
Rapidly growing primary cultures of normal human mammary epithelial cells (HMEC) were exposed to 1 microgram of benzo[a]pyrene (B[a]P) per ml for two or three 24-hr periods. The B[a]P-treated populations consistently contained cells displaying a long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d76bdb67103d6e4e7ec3360c564b6ee
https://europepmc.org/articles/PMC397564/
https://europepmc.org/articles/PMC397564/
We have studied the generation of reactive oxygen species during the metabolism of a carcinogen, benzo[a]pyrene, by human mammary epithelial cells. We have quantitated the production of one type of oxidative DNA damage, thymine glycols, by using a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8767bd9941c443a9e5e3d17df935897d
https://europepmc.org/articles/PMC280429/
https://europepmc.org/articles/PMC280429/
Autor:
Martha R. Stampfer, Jack C. Bartley
Publikováno v:
Carcinogenesis. 6(7)
We have examined the human mammary epithelial cell (HMEC) culture system developed in our laboratory for factors that might influence the metabolism of chemical carcinogens, specifically, the impact of interindividual variation and the effect of diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec76397277a8ac0b49b86ec061bf231
https://pubmed.ncbi.nlm.nih.gov/4017169
https://pubmed.ncbi.nlm.nih.gov/4017169