Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jack Bennink"'
Publikováno v:
The Journal of Immunology. 194:54.24-54.24
Protein translation is an essential and intricately regulated cellular process that can potentially be used to monitor immune cell activation. We extended the RiboPuromycylation Method (RPM) to measure protein translation in vivo. Unexpectedly, 24 h
Publikováno v:
The Journal of Immunology. 190:135.21-135.21
Protein translation is an essential and intricately regulated cellular process. We recently described the RiboPuroMycylation Method (RPM) to measure protein translation in cultured cells. RPM is based on ribosome-catalyzed addition of puromycin to na
Autor:
Pavlo Gilchuk, Charles Spencer, Stephanie Conant, Xinnan Niu, John Erickson, Kristi McAfee, Carla Oseroff, Sine Hadrup, Jack Bennink, William Hildebrand, Kathryn Edwards, James Crowe, Jr, John Williams, Søren Buus, Alessandro Sette, Ton Schumacher, Andrew Link, Sebastian Joyce
Publikováno v:
The Journal of Immunology. 188:113.11-113.11
Rational design of CD8+ T cell (TCD8)-based vaccines requires knowledge of the immunogenic and protective epitopes presented during infection, information which is currently lacking. Using the clinically successful smallpox vaccine as a model, ~200 n
Viral Infection Triggers Rapid Differentiation of Human Blood Monocytes into Dendritic Cells (45.12)
Autor:
Wanqiu Hou, James Gibbs, Xiuju Lu, Christopher Brooke, Devika Roy, Robert Modlin, Jack Bennink, Jonathan Yewdell
Publikováno v:
The Journal of Immunology. 188:45.12-45.12
Viruses post a constant threat of human existence. Although human immune system plays a central role in recognizing and eradicating pathogens, how it responds to virus infection remains unclear. Here we show that monocytes make up the majority of a w
Publikováno v:
The Journal of Immunology. 184:130.29-130.29
Defective Ribosomal Products (DRiPs) are an important source of MHC class I peptide ligands. How and where DRiPs are generated is an unanswered question with important implications for rationale design of T cell vaccines. To better understand DRiP an
Publikováno v:
European Journal of Immunology. 12:892-895
The frequency of mutant-specific cytotoxic T lymphocyte precursors (CTL-P) has been analyzed in several mouse strains. While H-2 antigens of responder strains have a limited influence on the frequency of major H antigen-specific CTL-P, the frequency
Publikováno v:
European Journal of Immunology. 12:887-892
The relative frequencies of cytotoxic T lymphocyte precursors (CTL-P) specific for minor histocompatibility antigens that are restricted to either k or b major histocompatibility complex antigens in normal B6 mice and in B6 leads to (B6 x CBA)F1 radi
Publikováno v:
Annales de l'Institut Pasteur / Immunologie. 134:17-24
Summary This report examines conflicting hypotheses concerning T-cell repertoire selection in terms of H-2 restriction during ontogeny. The experiments described in this report were incompatible with the hypothesis that bias in the repertoire is sole