Zobrazeno 1 - 10
of 411
pro vyhledávání: '"Jack A. YANOVSKI"'
Autor:
Theresa V. Strong, Jennifer L. Miller, Shawn E. McCandless, Evelien Gevers, Jack A. Yanovski, Lisa Matesevac, Jessica Bohonowych, Shaila Ballal, Kristen Yen, Patricia Hirano, Neil M. Cowen, Anish Bhatnagar
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Prader-Willi syndrome (PWS) is a rare neurobehavioral-metabolic disease caused by the lack of paternally expressed genes in the chromosome 15q11-q13 region, characterized by hypotonia, neurocognitive problems, behavioral difficult
Externí odkaz:
https://doaj.org/article/f5daf70833c04bcc97d36ae2f517d1a7
Autor:
Temesgen E. Andargie, Katerina Roznik, Neelam Redekar, Tom Hill, Weiqiang Zhou, Zainab Apalara, Hyesik Kong, Oren Gordon, Rohan Meda, Woojin Park, Trevor S. Johnston, Yi Wang, Sheila Brady, Hongkai Ji, Jack A. Yanovski, Moon K. Jang, Clarence M. Lee, Andrew H. Karaba, Andrea L. Cox, Sean Agbor-Enoh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Multisystem inflammatory syndrome in children (MIS-C) is a rare but life-threatening hyperinflammatory condition induced by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes pediatric COVID-19 (pCOVID-19). The re
Externí odkaz:
https://doaj.org/article/9dcf9edb519d4585810c8ca21afed2eb
Autor:
Meghan E. Byrne, Marian Tanofsky-Kraff, Lucrezia Liuzzi, Tom Holroyd, Megan N. Parker, Bess F. Bloomer, Allison Nugent, Sheila M. Brady, Shanna B. Yang, Sara A. Turner, Daniel S. Pine, Jack A. Yanovski
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionLoss-of-control (LOC) eating, a key feature of binge-eating disorder, may relate attentional bias (AB) to highly salient interpersonal stimuli. The current pilot study used magnetoencephalography (MEG) to explore neural features of AB to
Externí odkaz:
https://doaj.org/article/3a477ca701f446a183dd8a2a0e335040
Autor:
Olanrewaju A. Ogunleye, Harish Raviprakash, Ashlee M. Simmons, Rhasaan T.M. Bovell, Pedro E. Martinez, Jack A. Yanovski, Karen F. Berman, Peter J. Schmidt, Elizabeth C. Jones, Hadi Bagheri, Nadia M. Biassou, Li-Yueh Hsu
Publikováno v:
Tomography, Vol 9, Iss 1, Pp 139-149 (2023)
Background: The development of adipose tissue during adolescence may provide valuable insights into obesity-associated diseases. We propose an automated convolutional neural network (CNN) approach using Dixon-based magnetic resonance imaging (MRI) to
Externí odkaz:
https://doaj.org/article/816eee209bf045f58103607194eec338
Autor:
Adrian M. Wong, Tushar P. Patel, Elizabeth K. Altman, Nicol Tugarinov, Giampaolo Trivellin, Jack A. Yanovski
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 21-27 (2021)
The Tg(Adipoq-cre)1Evdr mouse has become an important tool in adipose tissue biology. However, the exact genomic transgene integration site has not been established. Using Targeted Locus Amplification (TLA) we found the transgene had integrated on mo
Externí odkaz:
https://doaj.org/article/a19e4e67404a4a9c8a251bd866f4b0ca
Autor:
Shannon E. Marwitz, Megan V. Gaines, Sheila M. Brady, Sarah J. Mi, Miranda M. Broadney, Susan Z. Yanovski, Van S. Hubbard, Jack A. Yanovski
Publikováno v:
Endocrinology and Metabolism, Vol 35, Iss 4, Pp 847-857 (2020)
Background Few studies using criterion measures of insulin sensitivity (SI) and insulin secretory capacity (ISC) have been conducted across puberty to adulthood. We examined how SI and ISC change from pre-puberty through adulthood. Methods Hyperglyce
Externí odkaz:
https://doaj.org/article/02f402a811d84781b83f85f6e108f6d9
Autor:
Youn Hee Jee, Mariam Gangat, Olga Yeliosof, Adrian G. Temnycky, Selena Vanapruks, Philip Whalen, Evgenia Gourgari, Cortney Bleach, Christine H. Yu, Ian Marshall, Jack A. Yanovski, Kathleen Link, Svetlana Ten, Jeffrey Baron, Sally Radovick
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
PurposeCongenital hypopituitarism usually occurs sporadically. In most patients, the etiology remains unknown.MethodsWe studied 13 children with sporadic congenital hypopituitarism. Children with non-endocrine, non-familial idiopathic short stature (
Externí odkaz:
https://doaj.org/article/773e06597021478bb0b5917abde9cc0c
Autor:
Katherine M. Cole, Shau-Ming Wei, Pedro E. Martinez, Tuong-Vi Nguyen, Michael D. Gregory, J. Shane Kippenhan, Philip D. Kohn, Steven J. Soldin, Lynnette K. Nieman, Jack A. Yanovski, Peter J. Schmidt, Karen F. Berman
Publikováno v:
NeuroImage, Vol 234, Iss , Pp 117970- (2021)
Delineating the relationship between human neurodevelopment and the maturation of the hypothalamic-pituitary-gonadal (HPG) axis during puberty is critical for investigating the increase in vulnerability to neuropsychiatric disorders that is well docu
Externí odkaz:
https://doaj.org/article/b7e90eaad3b646b196423a81b9440227
Autor:
Robert M. Haws, Gregory Gordon, Joan C. Han, Jack A. Yanovski, Guojun Yuan, Murray W. Stewart
Publikováno v:
Contemporary Clinical Trials Communications, Vol 22, Iss , Pp 100780- (2021)
Background: A phase 2 trial has suggested that treatment with the melanocortin-4 receptor (MC4R) agonist setmelanotide is associated with a decrease in hunger and weight-related outcomes in participants with Bardet-Biedl syndrome (BBS) and Alström s
Externí odkaz:
https://doaj.org/article/a77f739a9fab415cb93ab037fd5f77fc
Autor:
Bonggi Lee, Jashin Koo, Joo Yun Jun, Oksana Gavrilova, Yongjun Lee, Arnold Y. Seo, Dezmond C. Taylor-Douglas, Diane C. Adler-Wailes, Faye Chen, Ryan Gardner, Dimitri Koutzoumis, Roya Sherafat Kazemzadeh, Robin B. Roberson, Jack A. Yanovski
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The melanocortin receptor, MC3R, regulates organismal energy homeostasis. Here, Lee et al. create knock-in mice with the a mutated version of the human MC3R receptor found in obese children, and show these mice have more fat and smaller bone, yet are
Externí odkaz:
https://doaj.org/article/221cc26ea0964e6589ae36eae44b565c