Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jack A. Bates"'
Autor:
Vedran Vasic, Steffen Dickopf, Nadine Spranger, Rose-Sophie Rosenberger, Michaela Fischer, Klaus Mayer, Vincent Larraillet, Jack A. Bates, Verena Maier, Tatjana Sela, Bianca Nussbaum, Harald Duerr, Stefan Dengl, Ulrich Brinkmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The generation of antibody-drug conjugates with optimal functionality depends on many parameters. These include binder epitope, antibody format, linker composition, conjugation site(s), drug-to-antibody ratio, and conjugation method. The pro
Externí odkaz:
https://doaj.org/article/036b3d31ae614275ab825efcefdb518e
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Methods to control protein degradation usually require prior genetic engineering of each specific protein of interest. Here the authors present a toolbox for targeted depletion of endogenous proteins in cells and organisms, which is based on light- a
Externí odkaz:
https://doaj.org/article/e0b9331a777b4a65a1b6e1126958bf30
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Biological processes in development and disease are controlled by the abundance, localization and modification of cellular proteins. We have developed versatile tools based on recombinant E3 ubiquitin ligases that are controlled by light or drug indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693fca9dc55afa1cf18a923f77af241b
https://doaj.org/article/e0b9331a777b4a65a1b6e1126958bf30
https://doaj.org/article/e0b9331a777b4a65a1b6e1126958bf30
Autor:
Jack A. Bates, Christina Bielmeier, Ramya Balaji, Anne-Kathrin Classen, Alexander Hildebrand, Hartmann Harz, Cornelia Stadler
Publikováno v:
Scientific Reports
While calcium signaling in excitable cells, such as muscle or neurons, is extensively characterized, calcium signaling in epithelial tissues is little understood. Specifically, the range of intercellular calcium signaling patterns elicited by tightly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b89eedc081a5a276970b40e173fe3e
https://doi.org/10.1038/srep42786
https://doi.org/10.1038/srep42786