Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jack A Kornblatt"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0206338 (2019)
The native octameric structure of streptococcal enolase from Streptococcus pyogenes increasingly dissociates as amino acid residues are removed one by one from the carboxy-terminus. These truncations gradually convert native octameric enolase into mo
Externí odkaz:
https://doaj.org/article/49084ada2e01462d908bf3bc2be6c76c
Autor:
Sébastien P Blais, Jack A Kornblatt, Xavier Barbeau, Guillaume Bonnaure, Patrick Lagüe, Robert Chênevert, Jacques Lapointe
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121043 (2015)
For tRNA-dependent protein biosynthesis, amino acids are first activated by aminoacyl-tRNA synthetases (aaRSs) yielding the reaction intermediates aminoacyl-AMP (aa-AMP). Stable analogues of aa-AMP, such as aminoacyl-sulfamoyl-adenosines, inhibit the
Externí odkaz:
https://doaj.org/article/3b1d561ac2e54987ae808045ca1ea8dc
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135754 (2015)
The enolase produced by Streptococcus pyogenes is a homo-octamer whose overall shape resembles that of a donut. The octamer is best described as a tetramer of dimers. As such, it contains two types of interfaces. The first is common to almost all eno
Externí odkaz:
https://doaj.org/article/9a175d5046b043b7bceebbf8798e76e6
Autor:
Huaying Zhao, Rodolfo Ghirlando, Carlos Alfonso, Fumio Arisaka, Ilan Attali, David L Bain, Marina M Bakhtina, Donald F Becker, Gregory J Bedwell, Ahmet Bekdemir, Tabot M D Besong, Catherine Birck, Chad A Brautigam, William Brennerman, Olwyn Byron, Agnieszka Bzowska, Jonathan B Chaires, Catherine T Chaton, Helmut Cölfen, Keith D Connaghan, Kimberly A Crowley, Ute Curth, Tina Daviter, William L Dean, Ana I Díez, Christine Ebel, Debra M Eckert, Leslie E Eisele, Edward Eisenstein, Patrick England, Carlos Escalante, Jeffrey A Fagan, Robert Fairman, Ron M Finn, Wolfgang Fischle, José García de la Torre, Jayesh Gor, Henning Gustafsson, Damien Hall, Stephen E Harding, José G Hernández Cifre, Andrew B Herr, Elizabeth E Howell, Richard S Isaac, Shu-Chuan Jao, Davis Jose, Soon-Jong Kim, Bashkim Kokona, Jack A Kornblatt, Dalibor Kosek, Elena Krayukhina, Daniel Krzizike, Eric A Kusznir, Hyewon Kwon, Adam Larson, Thomas M Laue, Aline Le Roy, Andrew P Leech, Hauke Lilie, Karolin Luger, Juan R Luque-Ortega, Jia Ma, Carrie A May, Ernest L Maynard, Anna Modrak-Wojcik, Yee-Foong Mok, Norbert Mücke, Luitgard Nagel-Steger, Geeta J Narlikar, Masanori Noda, Amanda Nourse, Tomas Obsil, Chad K Park, Jin-Ku Park, Peter D Pawelek, Erby E Perdue, Stephen J Perkins, Matthew A Perugini, Craig L Peterson, Martin G Peverelli, Grzegorz Piszczek, Gali Prag, Peter E Prevelige, Bertrand D E Raynal, Lenka Rezabkova, Klaus Richter, Alison E Ringel, Rose Rosenberg, Arthur J Rowe, Arne C Rufer, David J Scott, Javier G Seravalli, Alexandra S Solovyova, Renjie Song, David Staunton, Caitlin Stoddard, Katherine Stott, Holger M Strauss, Werner W Streicher, John P Sumida, Sarah G Swygert, Roman H Szczepanowski, Ingrid Tessmer, Ronald T Toth, Ashutosh Tripathy, Susumu Uchiyama, Stephan F W Uebel, Satoru Unzai, Anna Vitlin Gruber, Peter H von Hippel, Christine Wandrey, Szu-Huan Wang, Steven E Weitzel, Beata Wielgus-Kutrowska, Cynthia Wolberger, Martin Wolff, Edward Wright, Yu-Sung Wu, Jacinta M Wubben, Peter Schuck
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126420 (2015)
Analytical ultracentrifugation (AUC) is a first principles based method to determine absolute sedimentation coefficients and buoyant molar masses of macromolecules and their complexes, reporting on their size and shape in free solution. The purpose o
Externí odkaz:
https://doaj.org/article/3bd91e8f42734f39965350067490e003
Autor:
Sébastien P Blais, Jack A Kornblatt, Xavier Barbeau, Guillaume Bonnaure, Patrick Lagüe, Robert Chênevert, Jacques Lapointe
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130238 (2015)
Externí odkaz:
https://doaj.org/article/a4b2038dc8224ef89ba2f82f8efa52c6
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88395 (2014)
The enolase from Streptococcus pyogenes (Str enolase F137L/E363G) is a homo-octamer shaped like a donut. Plasminogen (Pgn) is a monomeric protein composed of seven discrete separated domains organized into a lock washer. The enolase is known to bind
Externí odkaz:
https://doaj.org/article/0031b1a27f884444a4bd87dc0be8672d
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28481 (2011)
For years it has been clear that plasminogen from different sources and enolase from different sources interact strongly. What is less clear is the nature of the structures required for them to interact. This work examines the interaction between can
Externí odkaz:
https://doaj.org/article/c51f0c17ea604d46b532ee4b34af46fc
Autor:
Jack A Kornblatt
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6196 (2009)
Canine plasminogen is made up of seven domains. In each domain there are several cysteines that are linked by disulfide bonds. Reduction of a limited number of the cystines destabilizes the protein such that it precipitates. The bond or bonds that ar
Externí odkaz:
https://doaj.org/article/02e4324afaa44720b64fbf08ead75d5c
Publikováno v:
Biology, Vol 10, Iss 778, p 778 (2021)
Biology
Biology
On 26 July 2020, our colleague and friend Dr [...]
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0206338 (2019)
PLoS ONE, Vol 14, Iss 1, p e0206338 (2019)
The native octameric structure of streptococcal enolase from Streptococcus pyogenes increasingly dissociates as amino acid residues are removed one by one from the carboxy-terminus. These truncations gradually convert native octameric enolase into mo