Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Jack Price"'
Autor:
Leonard C. Steg, Gemma L. Shireby, Jennifer Imm, Jonathan P. Davies, Alice Franklin, Robert Flynn, Seema C. Namboori, Akshay Bhinge, Aaron R. Jeffries, Joe Burrage, Grant W. A. Neilson, Emma M. Walker, Leo W. Perfect, Jack Price, Grainne McAlonan, Deepak P. Srivastava, Nicholas J. Bray, Emma L. Cope, Kimberley M. Jones, Nicholas D. Allen, Ehsan Pishva, Emma L. Dempster, Katie Lunnon, Jonathan Mill, Eilis Hannon
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Induced pluripotent stem cells (iPSCs) and their differentiated neurons (iPSC-neurons) are a widely used cellular model in the research of the central nervous system. However, it is unknown how well they capture age-associated processes, par
Externí odkaz:
https://doaj.org/article/18efbbb134be4d4aa4a20747dc35b350
Autor:
Jack Price
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-9 (2020)
Abstract A number of clinical trials of cell therapies for autism spectrum disorder have been conducted, and some have published their outcomes. This review considers the data that have emerged from this small set of published trials, evaluates their
Externí odkaz:
https://doaj.org/article/90363d914956414684634edcbb910255
Publikováno v:
Thuret, S, Lee, H, Srivastava, D & Price, J 2023, ' In vitro characterization on the role of APOE polymorphism in human hippocampal neurogenesis ', Hippocampus, vol. 33, no. 4, pp. 322-346 . https://doi.org/10.1002/hipo.23502
Hippocampal neurogenesis (HN) is considered an important mechanism underlying lifelong brain plasticity, and alterations in this process have been implicated in early Alzheimer's disease progression. APOE polymorphism is the most common genetic risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec14a302b3776c8f609be67d36709cd
https://doi.org/10.1002/hipo.23502
https://doi.org/10.1002/hipo.23502
Autor:
Hyunah Lee, Paulina Nowosiad, Lucia M. Dutan Polit, Jack Price, Deepak P. Srivastava, Sandrine Thuret
Publikováno v:
F1000Research, Vol 9 (2020)
Apolipoprotein E (APOE) is a multifunctional protein that plays significant roles in important cellular mechanisms in peripheral tissues and is as well expressed in the central nervous system, notably by adult neural stem cells (NSCs) in the hippocam
Externí odkaz:
https://doaj.org/article/0253cb875db949b6832aaffcf64b39df
Autor:
Hyunah Lee, Paulina Nowosiad, Lucia M. Dutan Polit, Jack Price, Deepak P. Srivastava, Sandrine Thuret
Publikováno v:
F1000Research, Vol 9 (2020)
Apolipoprotein E (APOE) is a multifunctional protein that plays significant roles in important cellular mechanisms in peripheral tissues and is as well expressed in the central nervous system, notably by adult neural stem cells (NSCs) in the hippocam
Externí odkaz:
https://doaj.org/article/5d5d42147acd4ebf94454fe6394e5e39
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-9 (2018)
Abstract Background Deletions and mutations in the SHANK3 gene are strongly associated with autism spectrum disorder and underlie the autism-associated disorder Phelan–McDermid syndrome. SHANK3 is a scaffolding protein found at the post-synaptic me
Externí odkaz:
https://doaj.org/article/bc7203701d5b4f679027d2a1b382f843
Autor:
Aleksandra Maruszak, Edina Silajdžić, Hyunah Lee, Tytus Murphy, Benjamine Liu, Liu Shi, Chiara de Lucia, Abdel Douiri, Evgenia Salta, Alejo J Nevado, Charlotte E Teunissen, Pieter J Visser, Jack Price, Henrik Zetterberg, Simon Lovestone, Sandrine Thuret
Publikováno v:
Brain, 146(5), 2045-2058. Oxford University Press
Brain, 146, 2045-2058. Oxford University Press
Maruszak, A, Lee, H, Silajdzic, E, Murphy, T, Liu, B, Shi, L, De Lucia, C, Douiri, A, Salta, E, Nevado-Holgado, A J, Teunissen, C E, Jelle Visser, P, Price, J, Zetterberg, H, Lovestone, S & Thuret, S 2022, ' Predicting progression to Alzheimer’s disease with human hippocampal progenitors exposed to serum ', Brain . https://doi.org/10.1093/brain/awac472
Maruszak, A, Silajdžić, E, Lee, H, Murphy, T, Liu, B, Shi, L, de Lucia, C, Douiri, A, Salta, E, Nevado, A J, Teunissen, C E, Visser, P J, Price, J, Zetterberg, H, Lovestone, S & Thuret, S 2023, ' Predicting progression to Alzheimer's disease with human hippocampal progenitors exposed to serum ', Brain, vol. 146, no. 5, pp. 2045-2058 . https://doi.org/10.1093/brain/awac472
Brain, 146, 2045-2058. Oxford University Press
Maruszak, A, Lee, H, Silajdzic, E, Murphy, T, Liu, B, Shi, L, De Lucia, C, Douiri, A, Salta, E, Nevado-Holgado, A J, Teunissen, C E, Jelle Visser, P, Price, J, Zetterberg, H, Lovestone, S & Thuret, S 2022, ' Predicting progression to Alzheimer’s disease with human hippocampal progenitors exposed to serum ', Brain . https://doi.org/10.1093/brain/awac472
Maruszak, A, Silajdžić, E, Lee, H, Murphy, T, Liu, B, Shi, L, de Lucia, C, Douiri, A, Salta, E, Nevado, A J, Teunissen, C E, Visser, P J, Price, J, Zetterberg, H, Lovestone, S & Thuret, S 2023, ' Predicting progression to Alzheimer's disease with human hippocampal progenitors exposed to serum ', Brain, vol. 146, no. 5, pp. 2045-2058 . https://doi.org/10.1093/brain/awac472
Adult hippocampal neurogenesis is important for learning and memory and is altered early in Alzheimer's disease. As hippocampal neurogenesis is modulated by the circulatory systemic environment, evaluating a proxy of how hippocampal neurogenesis is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54607af71c847bfad2c81c38ab01838
https://cris.maastrichtuniversity.nl/en/publications/1167a72f-3597-4536-b944-c696ae5f4997
https://cris.maastrichtuniversity.nl/en/publications/1167a72f-3597-4536-b944-c696ae5f4997
Autor:
Jacqueline P. Robbins, Leo Perfect, Elena M. Ribe, Marcello Maresca, Adrià Dangla-Valls, Evangeline M. Foster, Richard Killick, Paulina Nowosiad, Matthew J. Reid, Lucia Dutan Polit, Alejo J. Nevado, Daniel Ebner, Mohammad Bohlooly-Y, Noel Buckley, Menelas N. Pangalos, Jack Price, Simon Lovestone
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Our understanding of the molecular processes underlying Alzheimer’s disease (AD) is still limited, hindering the development of effective treatments, and highlighting the need for human-specific models. Advances in identifying components of the amy
Externí odkaz:
https://doaj.org/article/cbd88ea3b15f4424a992edf8c0d98186
Autor:
Hanna J. Tadros, Swati Choudhry, Debra L. Kearney, Kyle Hope, Abigail Yesso, Christina Y. Miyake, Jack Price, Joseph Spinner, Hari Tunuguntla, Kriti Puri, William Dreyer, Susan W. Denfield
Publikováno v:
Pediatric transplantationREFERENCES.
Although ventricular failure is a late finding in adults with AC, we hypothesize that this is a presenting symptom in pediatric heart failure patients who undergo HT and that their ventricular arrhythmia burden could differentiate AC from other cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3683ba4b84099252c19dcc074fc1ea6a
https://pubmed.ncbi.nlm.nih.gov/36451335
https://pubmed.ncbi.nlm.nih.gov/36451335
Autor:
Matthew J. Reid, Maria Rogdaki, Lucia Dutan, Bjørn Hanger, Kaarin Sabad, Roland Nagy, Dwaipayan Adhya, Simon Baron-Cohen, Grainne McAlonan, Jack Price, Anthony C. Vernon, Oliver D. Howes, Deepak P. Srivastava
Publikováno v:
Schizophrenia research.
Microdeletions at the 22q11.2 locus are associated with increased risk for schizophrenia. Recent work has demonstrated that antipsychotic naïve 22q11.2 carriers display elevated levels of dopamine synthesis capacity (DSC) as assessed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f19bf7e705be783c758f0cce34d1b0
https://pubmed.ncbi.nlm.nih.gov/35701280
https://pubmed.ncbi.nlm.nih.gov/35701280