Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Autor: Heather J. Bax, Jitesh Chauhan, Chara Stavraka, Aida Santaolalla, Gabriel Osborn, Atousa Khiabany, Melanie Grandits, Jacobo López-Abente, Lais C. G. F. Palhares, Charleen Chan Wah Hak, Alexandra Robinson, Amy Pope, Natalie Woodman, Cristina Naceur-Lombardelli, Sadek Malas, Jack E. M. Coumbe, Mano Nakamura, Roman Laddach, Silvia Mele, Silvia Crescioli, Anna M. Black, Sara Lombardi, Silvana Canevari, Mariangela Figini, Ahmad Sayasneh, Sophia Tsoka, Kevin FitzGerald, Cheryl Gillett, Sarah Pinder, Mieke Van Hemelrijck, Rebecca Kristeleit, Sharmistha Ghosh, Ana Montes, James Spicer, Sophia N. Karagiannis, Debra H. Josephs

Publikováno v: Bax, H, Chauhan, J, Stavraka, C, Santaolalla, A, Osborn, G, Khiabany, A, Grandits, M, Lopez-Abente Muroz, J, Gusmao Ferreira, L C, Chan Wah Hak, C, Robinson, A, Pope, A, Woodman, N, Naceur-Lombardelli, C, Malas, S, Nakamura, M, Coumbe, J E M, Laddach, R, Mele, S, Crescioli, S, Black, A, Lombardi, S, Canevari, S, Figini, M, Sayasneh, A, Tsoka, S, FitzGerald, K, Gillett, C, Pinder, S, Van Hemelrijck, M, Kristeleit, R, Ghosh, S, Montes, A, Spicer, J, Karagiannis, S N & Josephs, D 2022, ' Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes ', British Journal of Cancer . https://doi.org/10.1038/s41416-022-02031-x

Background Survival rates for ovarian cancer remain poor, and monitoring and prediction of therapeutic response may benefit from additional markers. Ovarian cancers frequently overexpress Folate Receptor alpha (FRα) and the soluble receptor (sFRα)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540f460d63dc952bc739807eae588499
https://doi.org/10.1038/s41416-022-02031-x

BRAF inhibitors and their immunological effects in malignant melanoma

Autor: Rebecca Adams, Jack E M Coumbe, Ben G T Coumbe, Jennifer Thomas, Zena Willsmore, Marija Dimitrievska, Monica Yasuzawa-Parker, Maximilian Hoyle, Suhaylah Ingar, Jenny L C Geh, Alastair D MacKenzie Ross, Ciaran Healy, Sophie Papa, Katie E Lacy, Sophia N Karagiannis

Publikováno v: Adams, R, Coumbe, J E M, Coumbe, B G T, Thomas, J, Willsmore, Z, Dimitrievska, M, Yasuzawa-Parker, M, Hoyle, M, Ingar, S, Geh, J, MacKenzie Ross, A, Healy, C, Papa, S, Lacy, K E & Karagiannis, S N 2022, ' BRAF inhibitors and their immunological effects in malignant melanoma ', Expert Review Of Clinical Immunology, vol. 18, no. 4, pp. 347-362 . https://doi.org/10.1080/1744666X.2022.2044796

Introduction: The treatment of cutaneous melanoma has been revolutionized by the development of small-molecule inhibitors targeting the MAPK pathway, including inhibitors of BRAF (BRAFi) and MEK (MEKi), and immune checkpoint blockade antibodies, occu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ab9be0d9ed21e170e39875d482bfb4
https://pubmed.ncbi.nlm.nih.gov/35195495

Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes.

Autor: Bax, Heather J., Chauhan, Jitesh, Stavraka, Chara, Santaolalla, Aida, Osborn, Gabriel, Khiabany, Atousa, Grandits, Melanie, López-Abente, Jacobo, Palhares, Lais C. G. F., Chan Wah Hak, Charleen, Robinson, Alexandra, Pope, Amy, Woodman, Natalie, Naceur-Lombardelli, Cristina, Malas, Sadek, Coumbe, Jack E. M., Nakamura, Mano, Laddach, Roman, Mele, Silvia, Crescioli, Silvia

Publikováno v: British Journal of Cancer; Jan2023, Vol. 128 Issue 2, p342-353, 12p

International Aeronautical Maps: Discussion

Autor: Jack, E. M., Cohen, J. Waley, Lloyd, Captain, Hinks, A. R.

Publikováno v: The Geographical Journal, 1921 May 01. 57(5), 348-354.

Externí odkaz: https://www.jstor.org/stable/1780842

River-Flow Records: Discussion

Autor: Close, Charles, Jack, E. M., Sandford-Fawcett, E. A., MacAulay, F. W., Mill, H. R., MacKenzie, N. F., Dixon, S. M., Hogan, M. A., Glasspoole, J., McClean, W. N.

Publikováno v: The Geographical Journal, 1930 Jul 01. 76(1), 49-59.

Externí odkaz: https://www.jstor.org/stable/1784681