Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jacinth Abraham"'
Autor:
Eva Migon, M. Prakash Hande, Tak W. Mak, Bénédicte Lemmers, Laura Tamblyn, Anne Hakem, John Peter McPherson, Rama Khokha, Atsushi Hirao, Razqallah Hakem, Otto Sanchez-Sweatman, Elzbieta Matysiak-Zablocki, Jacinth Abraham, Jeremy A. Squire
Publikováno v:
Genes and Development
Genes and Development, Cold Spring Harbor Laboratory Press, 2004, 18 (10), pp.1144-1153. ⟨10.1101/gad.1192704⟩
Genes and Development, Cold Spring Harbor Laboratory Press, 2004, 18 (10), pp.1144-1153. ⟨10.1101/gad.1192704⟩
Disruption of Brca1 results in cellular demise or tumorigenesis depending on cellular context. Inactivation of p53 contributes to Brca1-associated tumor susceptibility. However the activation of p53-dependent checkpoint/apoptotic signaling in the abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076ba85bfc9978e4ee6cb555b707b57d
https://doi.org/10.1101/gad.1192704
https://doi.org/10.1101/gad.1192704
Autor:
Stephen C. West, Mary Ellen Moynahan, M. Prakash Hande, Bénédicte Lemmers, Peter McPherson, Amro Shehabeldin, Cheryl H. Arrowsmith, Richard Chahwan, Razqallah Hakem, Jacinth Abraham, Roland Kanaar, Charly Chahwan, Jeroen Essers, Alberto Ciccia, Aik Kia Khaw, Maria Jasin, Rob C. Laister, Katsuhiro Hanada
Publikováno v:
EMBO Journal, 22, 6137-6147. Wiley-Blackwell
EMBO Journal
EMBO Journal, EMBO Press, 2003, 22 (22), pp.6137-6147. ⟨10.1093/emboj/cdg580⟩
EMBO Journal
EMBO Journal, EMBO Press, 2003, 22 (22), pp.6137-6147. ⟨10.1093/emboj/cdg580⟩
Yeast and human Eme1 protein, in complex with Mus81, constitute an endonuclease that cleaves branched DNA structures, especially those arising during stalled DNA replication. We identified mouse Eme1, and show that it interacts with Mus81 to form a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6882cf133e3130f35a20ea566f79f16b
https://doi.org/10.1093/emboj/cdg580
https://doi.org/10.1093/emboj/cdg580
Publikováno v:
Oncogene. 18:1521-1527
The tumour suppressor gene product, p53, is involved in mediating cellular responses to DNA damage including growth arrest and/or apoptosis. The mechanism by which p53 protein senses the presence of damaged DNA is not understood. The possibility that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1241f697fb5aeadfebdb301bee6c72
https://doi.org/10.1038/sj.onc.1202454
https://doi.org/10.1038/sj.onc.1202454
Publikováno v:
Blood. 92:2977-2979
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe48617602d3a975000ee8a13c49fe0
https://doi.org/10.1182/blood.v92.8.2977
https://doi.org/10.1182/blood.v92.8.2977
Publikováno v:
Journal of molecular biology. 295(4)
The p53 tumor suppressor protein promotes cell cycle arrest or apoptosis in response to DNA damage and other forms of stress. p53 protein functions as a transcription factor by binding to specific DNA sequences and regulating the transcription of tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cd786914e72d819294eea341c78b47
https://pubmed.ncbi.nlm.nih.gov/10656795
https://pubmed.ncbi.nlm.nih.gov/10656795
Autor:
Jacinth Abraham, Bénédicte Lemmers, M.Prakash Hande, Mary Ellen Moynahan, Charly Chahwan, Alberto Ciccia, Jeroen Essers, Katsuhiro Hanada, Richard Chahwan, Aik Kia Khaw, Peter McPherson, Amro Shehabeldin, Rob Laister, Cheryl Arrowsmith, Roland Kanaar, Stephen C. West, Maria Jasin, Razqallah Hakem
Publikováno v:
EMBO Journal; 11/17/2003, Vol. 22 Issue 22, p6137, 11p