Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jacinda Ristov"'
Autor:
Roland Schuler, Michael Rotte, Yan-Ling He, Peter Gergely, Pascal Espie, Laurence Colin, Anita Auger, Heidi Mergentaler, Martha Hernandez‐Illas, James S. Rush, Jacinda Ristov, Julie Milojevic, Denise Sickert, Cyrielle Dupuy, Alexandre Avrameas, Edwige Chokote, Phillip Koo, Aurelie Verles, Andrea Groenewegen, Charles S. Tomek
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsReferences. 20(2)
Iscalimab is a fully human, CD40 pathway blocking, nondepleting monoclonal antibody being developed as an immunosuppressive agent. We describe a first-in-human, randomized, double-blind, placebo-controlled study investigating the safety, tolerability
Autor:
James S. Rush, Christoph Heusser, Dorothee Müller-Ristig, Peter Ulrich, Christian Bruns, Pascal Espie, Gautier Robert, Doris Weider, Patrick Schmutz, Serge Côté, Max Warncke, Jacinda Ristov, Frank Kolbinger, Francisco Cordoba-Castro, Thierry Flandre, Denise Sickert, Barbara Greutmann, Martin A. Schneider, Mirela Dimitrova
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18(12)
The CD40-CD154 costimulatory pathway is essential for T cell-dependent immune responses, development of humoral memory, and antigen presenting cell function. These immune functions have been implicated in the pathology of multiple autoimmune diseases