BMAL1 modulates senescence programming via AP-1.

Autor: Jachim SK; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA., Zhong J; Epigenomics Development Laboratory, Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA., Ordog T; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.; Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA., Lee JH; Epigenomics Development Laboratory, Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA.; Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA., Bhagwate AV; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA., Nagaraj NK; Department of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA., Westendorf JJ; Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA., Passos JF; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA., Matveyenko AV; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.; Department of Medicine, Division of Endocrinology, Metabolism, Diabetes, and Nutrition, Mayo Clinic, Rochester, MN 55905, USA., LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN 55905, USA.

Publikováno v: Aging [Aging (Albany NY)] 2023 Oct 10; Vol. 15 (19), pp. 9984-10009. Date of Electronic Publication: 2023 Oct 10.

Biomarkers of cellular senescence in idiopathic pulmonary fibrosis.

Autor: Aversa Z; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA., Atkinson EJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Carmona EM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA., White TA; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA., Heeren AA; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA., Jachim SK; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Zhang X; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA., Cummings SR; Departments of Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.; Research Institute, California Pacific Medical Center, San Francisco, CA, USA., Chiarella SE; Division of Allergic Diseases, Mayo Clinic, Rochester, MN, USA., Limper AH; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA., LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. lebrasseur.nathan@mayo.edu.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA. lebrasseur.nathan@mayo.edu.

Publikováno v: Respiratory research [Respir Res] 2023 Apr 07; Vol. 24 (1), pp. 101. Date of Electronic Publication: 2023 Apr 07.

Characterization of cellular senescence in aging skeletal muscle.

Autor: Zhang X; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.; These authors equally contributed to this work., Habiballa L; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Mayo clinic graduate school of biomedical science, rochester, MN, USA.; These authors equally contributed to this work., Aversa Z; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA., Ng YE; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Sakamoto AE; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Englund DA; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA., Pearsall VM; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., White TA; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA., Robinson MM; School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA., Rivas DA; Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, Massachusetts, USA., Dasari S; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA., Hruby AJ; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Lagnado AB; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Jachim SK; Mayo clinic graduate school of biomedical science, rochester, MN, USA., Granic A; NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK., Sayer AA; NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK., Jurk D; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Lanza IR; Division of Endocrinology, Mayo Clinic, Rochester, MN, USA., Khosla S; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA., Fielding RA; Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, Massachusetts, USA., Nair KS; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA., Schafer MJ; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., Passos JF; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA., LeBrasseur NK; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.; Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.

Publikováno v: Nature aging [Nat Aging] 2022 Jul; Vol. 2 (7), pp. 601-615. Date of Electronic Publication: 2022 Jul 15.