Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jacent, Nassuuna"'
Autor:
Agnes Natukunda, Ludoviko Zirimenya, Gyaviira Nkurunungi, Jacent Nassuuna, Ronald Nkangi, Alex Mutebe, Paul L. A. M. Corstjens, Govert J. van Dam, Alison M. Elliott, Emily L. Webb
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundVariations in vaccine responses have been observed between populations. A role for helminth infections has been proposed due to their immunomodulatory properties. In a secondary analysis of data from a randomised trial assessing effects of
Externí odkaz:
https://doaj.org/article/b752cd7cbedf43d482b6ed52c04bb11a
Autor:
Oscar Asanya Nyangiri, Julius Mulindwa, Joyce Namulondo, Anna Kitibwa, Jacent Nassuuna, Alison Elliott, Magambo Phillip Kimuda, Alex Boobo, Barbara Nerima, Moses Adriko, Nathan J Dunton, Gaganjit Kaur Madhan, Mark Kristiansen, Miriam Casacuberta-Partal, Harry Noyes, Enock Matovu, TrypanoGEN+ Research group of the H3Africa consortium
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011796 (2023)
BackgroundIndividuals genetically susceptible to high schistosomiasis worm burden may contribute disproportionately to transmission and could be prioritized for control. Identifying genes involved may guide development of therapy.Methodology/principa
Externí odkaz:
https://doaj.org/article/2ab6d4fb87d4440c8b600bae9a0b301a
Autor:
Joyce Namulondo, Oscar Asanya Nyangiri, Magambo Phillip Kimuda, Peter Nambala, Jacent Nassuuna, Moses Egesa, Barbara Nerima, Savino Biryomumaisho, Claire Mack Mugasa, Immaculate Nabukenya, Drago Kato, Alison Elliott, Harry Noyes, Robert Tweyongyere, Enock Matovu, Julius Mulindwa, TrypanoGEN+ research group of the H3Africa consortium
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011455 (2023)
Over 290 million people are infected by schistosomes worldwide. Schistosomiasis control efforts focus on mass drug treatment with praziquantel (PZQ), a drug that kills the adult worm of all Schistosoma species. Nonetheless, re-infections have continu
Externí odkaz:
https://doaj.org/article/852fe9f9296a4407b9141ae6ed2d0c3b
Autor:
Bridgious Walusimbi, Melissa A. E. Lawson, Jacent Nassuuna, David P. Kateete, Emily L. Webb, Richard K. Grencis, Alison M. Elliott
Publikováno v:
Frontiers in Microbiomes, Vol 2 (2023)
The gut microbiome is important in shaping human health. One key factor that has been proposed to affect the gut microbiome is helminth infection. Unravelling the association and/or interaction between helminth infections and the gut microbiome may r
Externí odkaz:
https://doaj.org/article/b60b3e702f864f849716c6e35d5dcbfe
Autor:
Julius Mulindwa, Joyce Namulondo, Anna Kitibwa, Jacent Nassuuna, Oscar Asanya Nyangiri, Magambo Phillip Kimuda, Alex Boobo, Barbara Nerima, Fred Busingye, Rowel Candia, Annet Namukuta, Ronald Ssenyonga, Noah Ukumu, Paul Ajal, Moses Adriko, Harry Noyes, Claudia J de Dood, Paul L A M Corstjens, Govert J van Dam, Alison M Elliott, Enock Matovu, TrypanoGEN+ Research group
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 7, p e0010570 (2022)
BackgroundKnowing the prevalence of schistosomiasis is key to informing programmes to control and eliminate the disease as a public health problem. It is also important to understand the impact of infection on child growth and development in order to
Externí odkaz:
https://doaj.org/article/c9d0c1f44ec946ffb7680ccffd5f1cbb
Autor:
Sokouri A. Edwige, Oscar A. Nyangiri, Estelle Mewamba, P.L.A.M Corstjens, Mathurin Koffi, Joyce Namulondo, G.J. van Dam, Gustave Simo, M. Casacuberta-Partal, Alison Elliott, Julius Mulindwa, Dieudonne Mumba, Harry Noyes, Kévin Karume, Bruno Bucheton, Enock Matovu, Jacent Nassuuna
Publikováno v:
AAS Open Research, Vol 4 (2021)
Background: Approximately 25% of the risk of Schistosoma mansoni is associated with host genetic variation. We will test 24 candidate genes, mainly in the Th2 and Th17 pathways, for association with S. mansoni infection intensity in four African coun
Externí odkaz:
https://doaj.org/article/6fbebc4753584ea5b8c3f4ef60ea5121
Autor:
Pontiano Kaleebu, Emily Webb, Moses Muwanga, Gyaviira Nkurunungi, Ludoviko Zirimenya, Agnes Natukunda, Jacent Nassuuna, Gloria Oduru, Caroline Ninsiima, Christopher Zziwa, Florence Akello, Robert Kizindo, Mirriam Akello, Anne Wajja, Henry Luzze, Stephen Cose, Alison M Elliott, Alison Elliott, Rebecca Amongin, Beatrice Nassanga, Irene Nambuya, Prossy Kabuubi, Emmanuel Niwagaba, Grace Kabami, Helen Akurut, Alex Mutebe, Milly Namutebi, Caroline Onen, Esther Nakazibwe, Josephine Tumusiime, Susan Amongi, Moses Sewankambo, Denis Nsubuga, Samuel Kiwanuka, Fred Kiwudhu, David Abiriga, Moses Kizza, Samsi Nansukusa, Hermelijn Smits, Maria Yazdanbakhsh, Govert van Dam, Paul Corstjens, Sarah Staedke, James Kaweesa, Edridah Tukahebwa, Elly Tumushabe, Prossy N Kabuubi, Joel Serubanja, Sarah G Staedke
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction Drivers of lower vaccine efficacy and impaired vaccine-specific immune responses in low-income versus high-income countries, and in rural compared with urban settings, are not fully elucidated. Repeated exposure to and immunomodulation b
Externí odkaz:
https://doaj.org/article/643aaddefec640b0a6665a679bdbd825
Autor:
Pontiano Kaleebu, Emily Webb, Moses Muwanga, Gyaviira Nkurunungi, Ludoviko Zirimenya, Agnes Natukunda, Jacent Nassuuna, Gloria Oduru, Caroline Ninsiima, Christopher Zziwa, Florence Akello, Robert Kizindo, Mirriam Akello, Anne Wajja, Henry Luzze, Stephen Cose, Alison M Elliott, Alison Elliott, Rebecca Amongin, Beatrice Nassanga, Irene Nambuya, Prossy Kabuubi, Emmanuel Niwagaba, Grace Kabami, Helen Akurut, Alex Mutebe, Milly Namutebi, Caroline Onen, Esther Nakazibwe, Josephine Tumusiime, Susan Amongi, Moses Sewankambo, Denis Nsubuga, Samuel Kiwanuka, Fred Kiwudhu, David Abiriga, Moses Kizza, Samsi Nansukusa, Hermelijn Smits, Maria Yazdanbakhsh, Govert van Dam, Paul Corstjens, Sarah Staedke, James Kaweesa, Edridah Tukahebwa, Elly Tumushabe
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction Vaccine-specific immune responses vary between populations and are often impaired in low income, rural settings. Drivers of these differences are not fully elucidated, hampering identification of strategies for optimising vaccine effecti
Externí odkaz:
https://doaj.org/article/c59ad65aaf42418f974c1aac6183eb0f
Autor:
Pontiano Kaleebu, Emily Webb, Moses Muwanga, Gyaviira Nkurunungi, Ludoviko Zirimenya, Agnes Natukunda, Jacent Nassuuna, Gloria Oduru, Caroline Ninsiima, Christopher Zziwa, Florence Akello, Robert Kizindo, Mirriam Akello, Anne Wajja, Henry Luzze, Stephen Cose, Alison M Elliott, Alison Elliott, Rebecca Amongin, Beatrice Nassanga, Irene Nambuya, Prossy Kabuubi, Emmanuel Niwagaba, Grace Kabami, Helen Akurut, Alex Mutebe, Milly Namutebi, Caroline Onen, Esther Nakazibwe, Josephine Tumusiime, Susan Amongi, Moses Sewankambo, Denis Nsubuga, Samuel Kiwanuka, Fred Kiwudhu, David Abiriga, Moses Kizza, Samsi Nansukusa, Hermelijn Smits, Maria Yazdanbakhsh, Govert van Dam, Paul Corstjens, Sarah Staedke, James Kaweesa, Edridah Tukahebwa, Elly Tumushabe, Prossy N Kabuubi, Joel Serubanja
Publikováno v:
BMJ Open, Vol 11, Iss 2 (2021)
Introduction Several licensed and investigational vaccines have lower efficacy, and induce impaired immune responses, in low-income versus high-income countries and in rural, versus urban, settings. Understanding these population differences is essen
Externí odkaz:
https://doaj.org/article/0046f191741b4bd285f9b6dcba978b90
Autor:
Richard E. Sanya, Irene Andia Biraro, Margaret Nampijja, Christopher Zziwa, Carol Nanyunja, Denis Nsubuga, Samuel Kiwanuka, Josephine Tumusiime, Jacent Nassuuna, Bridgious Walusimbi, Stephen Cose, Ponsiano Ocama, Richard K. Grencis, Alison M. Elliott, Emily L. Webb
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been linked to urbanisation. Helminths, through their immunomodulatory properties, may protect agains
Externí odkaz:
https://doaj.org/article/a85facfaaa67440bae11296820840253