Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jacelyn M. S. Loh"'
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 885-899 (2023)
Introduction The unique mucosal immune system allows the generation of robust protective immune responses at the front line of pathogen encounters. The needle-free delivery route and cold chain-free logistic requirements also provide additional advan
Externí odkaz:
https://doaj.org/article/54f2ae9b27594bed8d52b2b10d2df472
Autor:
Reuben McGregor, Aimee Paterson, Prachi Sharma, Tiffany Chen, Jarrod R. Lovell, Lauren H. Carlton, Andrew C. Steer, Joshua Osowicki, Jacelyn M. S. Loh, Nicole J. Moreland
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Group A Streptococcus (GAS) is a leading human pathogen for which there is no licensed vaccine. Infections are most common in young children and the elderly suggesting immunity accumulates with exposure until immune senescence in older age.
Externí odkaz:
https://doaj.org/article/e25b86a43fe942aa96e12a82aa053f80
Autor:
Farina Nor Hashimi, Julie Bennett, Michael G. Baker, Nicole J. Moreland, Troy L. Merry, Jacelyn M. S. Loh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-5 (2022)
Abstract The number of sugar-sweetened beverages consumed per day has been associated with an increased risk of acute rheumatic fever, an autoimmune disease triggered by superficial Streptococcus pyogenes infection. To explore if there could be a bio
Externí odkaz:
https://doaj.org/article/774a0a6ea62b4c92bc7090696dd8413b
Autor:
Jacelyn M. S. Loh, Tania Rivera-Hernandez, Reuben McGregor, Adrina Hema J. Khemlani, Mei Lin Tay, Amanda J. Cork, Jeremy M. Raynes, Nicole J. Moreland, Mark J. Walker, Thomas Proft
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Pili of Group A Streptococcus (GAS) are surface-exposed structures involved in adhesion and colonisation of the host during infection. The major protein component of the GAS pilus is the T-antigen, which multimerises to form the pilus shaft.
Externí odkaz:
https://doaj.org/article/e5c26595d82b49ec87d8e1591a0db673
Autor:
Jacelyn M. S. Loh, Natalie Lorenz, Catherine J.-Y. Tsai, Adrina Hema J. Khemlani, Thomas Proft
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The human pathogen Group A Streptococcus (GAS) produces pili that are involved in adhesion and colonisation of the host. These surface-exposed pili are immunogenic and therefore represent an attractive target for vaccine development. The pil
Externí odkaz:
https://doaj.org/article/efa58e577bca4160909851cb9564e2f3
Publikováno v:
Methods in Molecular Biology ISBN: 9781071632420
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ceac435bacb35eac76688dfb05b195
https://doi.org/10.1007/978-1-0716-3243-7_8
https://doi.org/10.1007/978-1-0716-3243-7_8
Autor:
Callum Chalmers, Jacelyn M. S. Loh, Chae Ryeong Sohn, Catherine Jia-Yun Tsai, Adrina Hema J. Khemlani, Thomas Proft
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 53, Iss 1, Pp 42-48 (2020)
Background: Streptococcus pyogenes, or Group A Streptococcus (GAS), is a human pathogen that causes a wide range of diseases, including pharyngitis, necrotizing fasciitis and toxic shock syndrome. The bacterium produces a large arsenal of virulence f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f5a6171ebeaefc50fcf3c617f9af43
http://www.sciencedirect.com/science/article/pii/S1684118217302360
http://www.sciencedirect.com/science/article/pii/S1684118217302360
Publikováno v:
Molecular Microbiology. 113:691-698
5'-nucleotidases (5'-NTs) are enzymes that catalyze the hydrolysis of nucleoside monophosphates to produce nucleosides and phosphate. Since the identification of adenosine synthase A (AdsA) in Staphylococcus aureus in 2009, several other 5'-NTs have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d15c7f0fe4ca6516acd2e3d20e0b243
https://doi.org/10.1111/mmi.14442
https://doi.org/10.1111/mmi.14442
Autor:
Haniyeh, Aghababa, Yi Tian, Ting, Devaki, Pilapitiya, Jacelyn M S, Loh, Paul G, Young, Thomas, Proft
Publikováno v:
Virulence
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Streptococcus pyogenes, a leading human pathogen, is responsible for a wide range of diseases, including skin and soft tissue infections and severe invasive diseases. S. pyogenes produces a large arsenal of virulence factors, including several immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18eea8c96aacbc24acd2c2b56b82c563
https://pubmed.ncbi.nlm.nih.gov/35094646
https://pubmed.ncbi.nlm.nih.gov/35094646
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2412
Peptide vaccines offer an attractive strategy to induce highly specific immune responses while reducing potential side effects. However, peptides are often poorly immunogenic and unstable on their own, requiring the need for potentially toxic adjuvan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e6f77b0fe1092cf9cdd9aec8c1bb06e
https://pubmed.ncbi.nlm.nih.gov/34918257
https://pubmed.ncbi.nlm.nih.gov/34918257