Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jacek Rozga"'
Autor:
Takeshi Aoki, Hongxiang Hui, Yutaka Umehara, Sergio Licalzi, Achilles A. Demetriou, Jacek Rozga M.D., Ph.D., Riccardo Perfetti
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Pancreatic islet transplantation is limited by shortage of donor organs. Although β-cell lines could be used, their secretion of insulin is characteristically glucose independent and immunoisolation is required. Here we show that intrasplenic transp
Externí odkaz:
https://doaj.org/article/bcadd889e7154c98b230101940d9a9ef
Autor:
Takeshi Aoki, Yutaka Umehara, Chiara Ferraresso, Nozomu Sugiyama, Yvette Middleton, Itzhak Avital, Daniel Inderbitzin, Achilles A. Demetriou, Jacek Rozga M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 11 (2002)
Cell therapy is likely to succeed clinically if cells survive at the transplantation site and are protected against immune rejection. We hypothesized that this could be achieved with intrasplenic transplantation of encapsulated cells because the cell
Externí odkaz:
https://doaj.org/article/9eb88551f68d4b2a8f27ef085f56d5e8
Autor:
Eugenio Morsiani, Luciano Fogli M.D., Giovanni Lanza, Laura T. Lebow, Achilles A. Demetriou, Jacek Rozga
Publikováno v:
Cell Transplantation, Vol 11 (2002)
Clinical islet transplantation (Tx) in type I diabetic patients has been successful so far only in a minority of cases, probably because of multiple factors, partly immunologic and partly nonimmunologic in nature. Pre-clinical studies of islet Tx in
Externí odkaz:
https://doaj.org/article/920e675ebaa74762b0c4f6ea71527b05
Autor:
Nikolaos Arkadopoulos, Steve C. Chen, Theodore M. Khalili, Olivier Detry, Winston R. Hewitt, Helene Lilja, Hirofumi Kamachi, Lidija Petrovic, Claudy J.P. Mullon, Achilles A. Demetriou, Jacek Rozga M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 7 (1998)
Intracranial hypertension leading to brain stem herniation is a major cause of death in fulminant hepatic failure (FHF). Mannitol, barbiturates, and hyperventilation have been used to treat brain swelling, but most patients are either refractory to m
Externí odkaz:
https://doaj.org/article/de403cf0a36c46a287cd50bb903347a8
Publikováno v:
Cell Transplantation, Vol 7 (1998)
Hepatocyte transplantation is a promising alternative to orthotopic liver transplantation in experimental animal models with genetic disorders of liver metabolism and liver failure. Fetal hepatocytes have several characteristics that make them potent
Externí odkaz:
https://doaj.org/article/82217d5cbfaa4872a5c10e1614596b3f
Publikováno v:
Cell Transplantation, Vol 6 (1997)
Poor engraftment and consequent loss of β-cell mass could be one of the factors that are responsible for function loss after intraportal islet transplantation (Tx). Streptozotocin-diabetic rats were transplanted with syngeneic islets, which were inj
Externí odkaz:
https://doaj.org/article/0b78cf4efd5b4a678c393dc4afb2d9ab
Autor:
Albert D. Moscioni, Jacek Rozga M.D., Ph.D., Steve Chen, Arjang Nam, Henri S. Scott, Achilles A. Demetriou
Publikováno v:
Cell Transplantation, Vol 5 (1996)
Numerous studies have reported successful transplantation of hepatocytes with demonstration of function. However, none have shown long-term correction of a liver-related metabolic defect. Male Nagase analbuminemic rats, immunosuppressed with cyclospo
Externí odkaz:
https://doaj.org/article/f2daceb4bff2467e8fd17b6a68fe14d8
Autor:
Jacek Rozga, Michael Holzman, Albert D. Moscioni, Hikaro Fujioka, Eugenio Morsiani, Achilles A. Demetriou
Publikováno v:
Cell Transplantation, Vol 4 (1995)
The optimal site for implantation of isolated hepatocytes has not been established. We have developed a novel technique which allows repeated infusion of hepatocytes into the portal system via an indwelling catheter. Seven Nagase Analbuminemic rats (
Externí odkaz:
https://doaj.org/article/010016c93a6f4fcbab60d19b0cff48af
Autor:
Hikaru Fujioka, Peter J. Hunt, Jacek Rozga, Guo-Du Wu, Donald V. Cramer, Achilles A. Demetriou, Albert D. Moscioni
Publikováno v:
Cell Transplantation, Vol 3 (1994)
Renewed interest in the transplantation of isolated hepatocytes into the liver as a potential therapy for liver disease has stimulated the development of methods for the identification of donor cells within the recipient organ. We describe a method f
Externí odkaz:
https://doaj.org/article/89bfca4046fd46089e90d49b2a367a4e
Autor:
Jacek Rozga, Joanna Raszeja-Wyszomirska, Marta Hreńczuk, Agata Rozga, Piotr Małkowski, Grzegorz Niewiński
Publikováno v:
Artificial Organs. 44:91-99
Acute-on-chronic liver failure (ACLF) requiring intensive medical care and associated with acute kidney injury (AKI) has a mortality rate as high as 90% due to the lack of effective therapies. In this study, we assessed the effects of intermittent hi