Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jacek Kujawski"'
Autor:
Dorota Olender, Jacek Kujawski, Bartosz Skóra, Ewa Baranowska-Wójcik, Katarzyna Sowa-Kasprzak, Anna Pawełczyk, Lucjusz Zaprutko, Dominik Szwajgier, Konrad A. Szychowski
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37147- (2024)
In the area of research on neurodegenerative diseases, the current challenge is to search for appropriate research methods that would detect these diseases at the earliest possible stage, but also new active structures that would reduce the rate of t
Externí odkaz:
https://doaj.org/article/995f3b675c004e84a564ff285bc4a5f5
Autor:
Wojciech Szczolko, Kyrylo Chornovolenko, Jacek Kujawski, Zbigniew Dutkiewicz, Tomasz Koczorowski
Publikováno v:
Molecules, Vol 29, Iss 15, p 3610 (2024)
The presented studies aimed to evaluate the peripheral coordinating properties of a novel porphyrinoid family representative preceded by its synthesis for potential sensing purposes. Two synthetic pathways were employed to a obtain maleonitrile deriv
Externí odkaz:
https://doaj.org/article/4c355722d55e4ef1bf3f657a0f990325
Autor:
Katarzyna Sowa-Kasprzak, Ewa Totoń, Jacek Kujawski, Dorota Olender, Natalia Lisiak, Lucjusz Zaprutko, Błażej Rubiś, Mariusz Kaczmarek, Anna Pawełczyk
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1506 (2023)
Curcumin and oleanolic acid are natural compounds with high potential in medicinal chemistry. These products have been widely studied for their pharmacological properties and have been structurally modified to improve their bioavailability and therap
Externí odkaz:
https://doaj.org/article/a91466fc188d4fc5880a590827437644
Autor:
Beata Drabińska, Katarzyna Dettlaff, Tomasz Ratajczak, Kacper Kossakowski, Marcin K. Chmielewski, Judyta Cielecka-Piontek, Jacek Kujawski
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 520 (2022)
The paper compares the experimental FT-IR, UV-vis, and 1H NMR spectra of isoconazole and bifonazole with the density functional theory (DFT) calculations using different functionals. The results were compared with previously reported data related to
Externí odkaz:
https://doaj.org/article/872eed80d29b4539bdcf3addb9cc1c3b
Autor:
Paulina Kobylka, Malgorzata Kucinska, Jacek Kujawski, Dawid Lazewski, Marcin Wierzchowski, Marek Murias
Publikováno v:
Molecules, Vol 27, Iss 20, p 6973 (2022)
Resveratrol is a plant-derived phytoalexin found in grapes, red wine and many other plants used in Asian folk medicine. It is extensively studied for pleiotropic biological activity. The most crucial are anticancer and chemopreventive properties. Res
Externí odkaz:
https://doaj.org/article/ae41fa2712eb49fb9ab9dd98ab8bc0c0
Autor:
Dawid Lazewski, Malgorzata Kucinska, Edward Potapskiy, Joanna Kuzminska, Artur Tezyk, Lukasz Popenda, Stefan Jurga, Anna Teubert, Zofia Gdaniec, Jacek Kujawski, Katarzyna Grzyb, Tomasz Pedzinski, Marek Murias, Marcin Wierzchowski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10029 (2022)
This work presents the synthesis and characterization of metal-free, zinc (II), and cobalt (II) porphyrins substituted with short PEG chains. The synthesized compounds were characterized by UV-Vis, 1H and 13C NMR spectroscopy, and MALDI-TOF mass spec
Externí odkaz:
https://doaj.org/article/c7345a89e3274fbda07ed4bf89f92445
Autor:
Natalia Magdalena Lisiak, Izabela Lewicka, Mariusz Kaczmarek, Jacek Kujawski, Barbara Bednarczyk-Cwynar, Lucjusz Zaprutko, Blazej Rubis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11273 (2021)
Approximately 20–30% of the diagnosed breast cancers overexpress the human epidermal growth factor receptor 2 (HER2). This type of cancer is associated with a more aggressive phenotype; thus, there is a need for the discovery of new compounds that
Externí odkaz:
https://doaj.org/article/d9530e28b20d4747b164e9cec3a2dc7c
Autor:
Maria Narożna, Violetta Krajka-Kuźniak, Barbara Bednarczyk-Cwynar, Małgorzata Kucińska, Robert Kleszcz, Jacek Kujawski, Hanna Piotrowska-Kempisty, Adam Plewiński, Marek Murias, Wanda Baer-Dubowska
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 688 (2021)
Combining NSAIDs with conventional therapeutics was recently explored as a new strategy in cancer therapy. Our earlier studies showed that novel oleanolic acid oximes (OAO) conjugated with aspirin or indomethacin may enhance their anti-cancer potenti
Externí odkaz:
https://doaj.org/article/39cc15d5559647a6ac4e1d3132e51342
Autor:
Marcin Skotnicki, Barbara Jadach, Agnieszka Skotnicka, Bartłomiej Milanowski, Lidia Tajber, Marek Pyda, Jacek Kujawski
Publikováno v:
Pharmaceutics, Vol 13, Iss 1, p 118 (2021)
The aim of this study was to characterize a 1:1 molar ratio of a pharmacologically relevant co-amorphous atorvastatin-irbesartan (ATR-IRB) system obtained by quench cooling of the crystalline ATR/IRB physical mixture for potential use in the fixed-do
Externí odkaz:
https://doaj.org/article/ce3390e283644d56b9a71e9975a3e90d
Autor:
Kornelia Czaja, Jacek Kujawski, Urlich Girreser, Jarosław J. Panek, Marek Doskocz, Marek K. Bernard
Publikováno v:
ARKIVOC, Vol 2016, Iss 4, Pp 22-43 (2016)
Externí odkaz:
https://doaj.org/article/716d83766eed414a9a072378a0a45691