Zobrazeno 1 - 10
of 726
pro vyhledávání: '"Jacek, Jassem"'
Autor:
Karolina Wojciechowicz, Katarzyna Kuncewicz, Jacek Rutkowski, Jacek Jassem, Sylwia Rodziewicz-Motowidło, Anna Wardowska, Marta Spodzieja
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116675- (2024)
The complex of B- and T-lymphocyte attenuator (BTLA) and herpes virus entry mediator (HVEM) plays a critical role in immune regulation and has emerged as a promising therapeutic target for cancer treatment. In this study, we investigated the potentia
Externí odkaz:
https://doaj.org/article/5dfae8d23e55421994ded3eab209b991
Autor:
Maksym A. Jopek, Krzysztof Pastuszak, Sebastian Cygert, Myron G. Best, Thomas Wurdinger, Jacek Jassem, Anna J. Zaczek, Anna Supernat
Publikováno v:
IEEE Journal of Translational Engineering in Health and Medicine, Vol 12, Pp 306-313 (2024)
The field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging metho
Externí odkaz:
https://doaj.org/article/f8bdbbadc6a4484d810ec5d2b00b4317
Autor:
Karolina Wojciechowicz, Katarzyna Kuncewicz, Jacek Rutkowski, Jacek Jassem, Anna Wardowska, Marta Spodzieja
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe effector function of T cells is regulated via immune checkpoints, activating or inhibiting the immune response. The BTLA-HVEM complex, the inhibitory immune checkpoint, may act as one of the tumor immune escape mechanisms. Therefore,
Externí odkaz:
https://doaj.org/article/95f6d24fdd1141448d7f04dd8fa0a2e0
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Breast cancer brain metastasis (BCBM) has a devastating impact on patient survival, cognitive function and quality of life. Radiotherapy remains the standard management of BM but may result in considerable neurotoxicity. Herein, we describe the curre
Externí odkaz:
https://doaj.org/article/d6b2a5ec449847d0990c8255ebd9086b
Publikováno v:
Cambridge Prisms: Precision Medicine, Vol 2 (2024)
Precision oncology is a rapidly evolving concept that holds great promise in cancer treatment. However, a cancer complexity attributed to genomic and acquired tumour heterogeneity limits treatment effectiveness and increases toxicity. These limitatio
Externí odkaz:
https://doaj.org/article/530ab4544bef4b0fadb5b067bb0cab02
Autor:
Robert Johnston, Hartmut Koeppen, Roy S Herbst, Kurt Schalper, Filippo De Marinis, Giuseppe Giaccone, Jacek Jassem, Marcus Ballinger, Barani Kumar Rajendran, David R Spigel, Miguel López de Rodas, Minu K Srivastava, Jennifer M Giltnane, Barzin Y Nabet, David S Shames, Velimir Gayevskiy, Vy Ma, Ivette Estay, Tien Hoang, Reena Amin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/49316787c82b4055a76f2b4631e47f3f
Autor:
Natalia Cichowska-Cwalińska, Michał Bieńkowski, Marta Popęda, Magdalena Dróżka, Jacek Rutkowski, Jacek Jassem, Renata Zaucha
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
AimWe hypothesized that markers of inflammation correlate with response to radiotherapy in patients with non-metastatic laryngeal cancer (LC). Our aim was to assess peripheral and local markers of inflammation including lymphocyte to monocyte ratio (
Externí odkaz:
https://doaj.org/article/acb444075e4c4f409c770e214daca5df
Autor:
Renata Duchnowska, Anna Maria Supernat, Rafał Pęksa, Marta Łukasiewicz, Tomasz Stokowy, Roy Ronen, Janusz Dutkowski, Monika Umińska, Ewa Iżycka-Świeszewska, Anna Kowalczyk, Waldemar Och, Monika Rucińska, Wojciech P. Olszewski, Tomasz Mandat, Bożena Jarosz, Michał Bieńkowski, Wojciech Biernat, Jacek Jassem
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing analysis of ten matc
Externí odkaz:
https://doaj.org/article/d2d11a695913453e8ed1c77cf42a380f
Autor:
Adrian Perdyan, Jacek Jassem
Publikováno v:
Current Oncology, Vol 29, Iss 4, Pp 2284-2300 (2022)
The carcinogenic role of tobacco smoking is well recognized, but the detrimental effects of continued smoking after a cancer diagnosis have been underestimated. Radiotherapy is among the main treatment modalities for cancer. We reviewed the literatur
Externí odkaz:
https://doaj.org/article/b32d5d9fcf544452b496cd1e94a332b2
Autor:
Marcin Nicoś, PhD, Luuk Harbers, MSc, Enrico Patrucco, PhD, Maximilian Kramer-Drauberg, PhD, Xiaolu Zhang, PhD, Claudia Voena, PhD, Anna Kowalczyk, MD, PhD, Aleksandra Bożyk, PhD, Rafał Pęksa, MD, PhD, Bożena Jarosz, MD, PhD, Justyna Szumiło, MD, Michele Simonetti, PhD, Monika Żuk, PhD, Bartosz Wasąg, MD, Katarzyna Reszka, PhD, Renata Duchnowska, MD, Janusz Milanowski, MD, Roberto Chiarle, MD, Magda Bienko, PhD, Paweł Krawczyk, MD, Jacek Jassem, MD, Chiara Ambrogio, PhD, Nicola Crosetto, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 12, Pp 100435- (2022)
Introduction: Brain metastases (BM) severely affect the prognosis and quality of life of patients with NSCLC. Recently, molecularly targeted agents were found to have promising activity against BM in patients with NSCLC whose primary tumors carry “
Externí odkaz:
https://doaj.org/article/93978b32039848998a35af7844ee33cf