Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice.

Autor: Ulschmid CM; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Sun MR; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Jabbarpour CR; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Steward AC; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Rivera-González KS; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.; Molecular and Environmental Toxicology Training Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706., Cao J; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Martin AA; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Barnes M; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Wicklund L; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Madrid A; Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706., Papale LA; Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706., Joseph DB; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706., Vezina CM; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.; Molecular and Environmental Toxicology Training Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706., Alisch RS; Neurological Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706., Lipinski RJ; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.; Molecular and Environmental Toxicology Training Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jan 16; Vol. 121 (3), pp. e2317668121. Date of Electronic Publication: 2024 Jan 09.

Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate.

Autor: Robinson K; Department of Human Genetics, Emory University, Atlanta, GA., Mosley TJ; Department of Human Genetics, Emory University, Atlanta, GA.; Current address: Chief Officer for Scientific Workforce Diversity Office, National Institutes of Health, Bethesda, MD., Rivera-González KS; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI., Jabbarpour CR; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI., Curtis SW; Department of Human Genetics, Emory University, Atlanta, GA., Adeyemo WL; Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Lagos, Nigeria., Beaty TH; Department of Epidemiology, Johns Hopkins University, Baltimore, MD., Butali A; Department of Oral Biology, Radiology, and Medicine, University of Iowa, Iowa City, IA., Buxó CJ; School of Dental Medicine, University of Puerto Rico, San Juan, Puerto Rico., Cutler DJ; Department of Human Genetics, Emory University, Atlanta, GA., Epstein MP; Department of Human Genetics, Emory University, Atlanta, GA., Gowans LJ; Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Hecht JT; Department of Pediatrics, McGovern Medical School University of Texas Health at Houston, Houston, TX., Murray JC; Department of Pediatrics, University of Iowa, Iowa City, IA., Shaw GM; Department of Pediatrics, Stanford University, Stanford, CA., Uribe LM; Department of Orthodontics & The Iowa Institute for Oral Health Research, University of Iowa, Iowa City, IA, USA., Weinberg SM; Center for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, School of Dental Medicine, and Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA., Brand H; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA., Marazita ML; Center for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, School of Dental Medicine, and Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA., Lipinski RJ; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI., Leslie EJ; Department of Human Genetics, Emory University, Atlanta, GA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Apr 06. Date of Electronic Publication: 2023 Apr 06.