Zobrazeno 1 - 10
of 457
pro vyhledávání: '"Jab1"'
Akademický článek
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Autor:
Yonghua Guo, Meng Gao, Ye Yao, Jinghua Li, Xi Chen, Xingxing Wang, Zhang Chen, Yufeng Yuan, Weijie Ma
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Despite the understanding of the COP9 signalosome subunit 5 (CSN5) in tumor genesis, there is no conclusive evidence on its value to predict the survival and prognosis of digestive system tumor patients. Hence this study aimed to
Externí odkaz:
https://doaj.org/article/b41a45e6efec4a50ba8a32ab86146c1e
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundNasopharyngeal carcinoma (NPC) is the most common subcategory of head and neck squamous cell carcinoma (HNSCC). This study focused on the roles of cuproptosis related genes and Jab1 in the tumor microenvironment of NPC and HNSCC.MethodsDiff
Externí odkaz:
https://doaj.org/article/69752aa731ca45c9b9057335247fd79c
Publikováno v:
Thoracic Cancer, Vol 11, Iss 4, Pp 973-982 (2020)
Background This study investigated the expression and biological function of JAB1 in esophageal squamous cell carcinoma (ESCC). Methods The expression of JAB1 in ESCC tissues and cells was measured using reverse transcriptase‐polymerase chain react
Externí odkaz:
https://doaj.org/article/f6cf8bd1ce044e76b7e453e4425cfe1f
Autor:
Yongguang Yang, Marissa Leonard, Zhenhua Luo, Syn Yeo, Gregory Bick, Mingang Hao, Chunmiao Cai, Mahmoud Charif, Jiang Wang, Jun-Lin Guan, Elyse E. Lower, Xiaoting Zhang
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108822- (2021)
Summary: MED1 (mediator subunit 1) co-amplifies with HER2, but its role in HER2-driven mammary tumorigenesis is still unknown. Here, we generate MED1 mammary-specific overexpression mice and cross them with mouse mammary tumor virus (MMTV)-HER2 mice.
Externí odkaz:
https://doaj.org/article/7c097196109c4077a33168b50f10e347
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 2126-2135 (2018)
Background/Aims: MicroRNAs (miRNAs) regulate the expressions of cancer-related genes, and are involved in the development and progression of various human cancers. Here, we performed further analyses to determine whether let-7d is functionally linked
Externí odkaz:
https://doaj.org/article/65ff00ea5095463ba7c86222af136221
Autor:
Jakub Ridl, Jachym Suman, Serena Fraraccio, Miluse Hradilova, Michal Strejcek, Tomas Cajthaml, Andrea Zubrova, Tomas Macek, Hynek Strnad, Ondrej Uhlik
Publikováno v:
Standards in Genomic Sciences, Vol 13, Iss 1, Pp 1-10 (2018)
Abstract In this study, following its isolation from contaminated soil, the genomic sequence of Pseudomonas alcaliphila strain JAB1 (=DSM 26533), a biphenyl-degrading bacterium, is reported and analyzed in relation to its extensive degradative capabi
Externí odkaz:
https://doaj.org/article/4fe52b643de348c9b8f28c08e12b0668
Publikováno v:
Molecules, Vol 26, Iss 18, p 5529 (2021)
Rutin has been well recognized for possessing numerous pharmacological and biological activities in several human cancer cells. This research has addressed the inhibitory potential of rutin against the Jab1 oncogene in SiHa cancer cells, which is kno
Externí odkaz:
https://doaj.org/article/5dabcc78da704edfa5ffeff5bdf605b5
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8839 (2021)
Synaptonemal complex protein 3 (SCP3), a member of the Cor1 family, has been implicated in cancer progression, and therapeutic resistance, as well as cancer stem cell (CSC)-like properties. Previously, we demonstrated that SCP3 promotes these aggress
Externí odkaz:
https://doaj.org/article/51f7070e970b4c9099a1912b1d2a37aa