Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts.

Autor: Foo B; Department of Cardiology and Pneumology, Heart Research Center Göttingen, Cellular Biophysics and Translational Cardiology Section, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Amedei H; Department of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany., Kaur S; Department of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany., Jaawan S; Department of Cardiology and Pneumology, Heart Research Center Göttingen, Cellular Biophysics and Translational Cardiology Section, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Boshnakovska A; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany., Gall T; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany., de Boer RA; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Cardiology, Erasmus MC, Thorax Center, Cardiovascular Institute, Rotterdam, the Netherlands., Silljé HHW; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Urlaub H; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; Department of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany.; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Rehling P; Department of Cellular Biochemistry, University Medical Center Göttingen, Göttingen, Germany., Lenz C; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; Department of Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany.; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Lehnart SE; Department of Cardiology and Pneumology, Heart Research Center Göttingen, Cellular Biophysics and Translational Cardiology Section, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.

Publikováno v: PloS one [PLoS One] 2024 Oct 24; Vol. 19 (10), pp. e0311203. Date of Electronic Publication: 2024 Oct 24 (Print Publication: 2024).