Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Jaap Middeldorp"'
1
Akademický článek
Cumulative Roles for different Viruses in Driving an Inflammatory Cascade Underlying MS Pathogenesis
Autor: Ute-Christiane Meier, Richard C Cipian, Abbas Karimi, Ranjan Ramasamy, Jaap Middeldorp
Publikováno v: Journal of Affective Disorders Reports, Vol 12, Iss , Pp 100552- (2023)
Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of intense research. Epstein-Barr virus (EBV), as a persistent and frequently reactivating
Externí odkaz: https://doaj.org/article/38afeb7b558f4a2cbfc7b284f943e8c5
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2
Akademický článek
Epidemiology of Epstein-Barr virus infection and infectious mononucleosis in the United Kingdom
Autor: Ashvin Kuri, Benjamin Meir Jacobs, Nikki Vickaryous, Julia Pakpoor, Jaap Middeldorp, Gavin Giovannoni, Ruth Dobson
Publikováno v: BMC Public Health, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Epstein-Barr Virus (EBV) is a ubiquitous gamma-herpesvirus with which ~ 95% of the healthy population is infected. EBV infection has been implicated in a range of haematological malignancies and autoimmune diseases. Delayed primar
Externí odkaz: https://doaj.org/article/2e9e933ddce74bbfbb505c51c55e3bef
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3
Akademický článek
Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
Autor: Weitao Lin, Yim Ling Yip, Lin Jia, Wen Deng, Hong Zheng, Wei Dai, Josephine Mun Yee Ko, Kwok Wai Lo, Grace Tin Yun Chung, Kevin Y. Yip, Sau-Dan Lee, Johnny Sheung-Him Kwan, Jun Zhang, Tengfei Liu, Jimmy Yu-Wai Chan, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, John Malcolm Nicholls, Pierre Busson, Xuefeng Liu, Alan Kwok Shing Chiang, Kwai Fung Hui, Hin Kwok, Siu Tim Cheung, Yuk Chun Cheung, Chi Keung Chan, Bin Li, Annie Lai-Man Cheung, Pok Man Hau, Yuan Zhou, Chi Man Tsang, Jaap Middeldorp, Honglin Chen, Maria Li Lung, Sai Wah Tsao
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The lack of appropriate models restricts pre-clinical research for nasopharyngeal carcinoma (NPC). Here the authors report the development and characterization of NPC patient-derived xenografts (PDXs), and EBV positive NPC cell line from patient tumo
Externí odkaz: https://doaj.org/article/0bf1deca4e9646d1b93328014cc28ef0
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4
Akademický článek
A novel persistence associated EBV miRNA expression profile is disrupted in neoplasia.
Autor: Jin Qiu, Katherine Cosmopoulos, Michiel Pegtel, Erik Hopmans, Paul Murray, Jaap Middeldorp, Michael Shapiro, David A Thorley-Lawson
Publikováno v: PLoS Pathogens, Vol 7, Iss 8, p e1002193 (2011)
We have performed the first extensive profiling of Epstein-Barr virus (EBV) miRNAs on in vivo derived normal and neoplastic infected tissues. We describe a unique pattern of viral miRNA expression by normal infected cells in vivo expressing restricte
Externí odkaz: https://doaj.org/article/b26f0e6d23a74156b9b7c71786d198c0
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10
Data from Reconstitution of Nasopharyngeal Carcinoma–Type EBV Infection Induces Tumorigenicity
Autor: Kenzo Takada, Jaap Middeldorp, Tadamasa Ooka, Eri Seto
Several reports have shown that the EBV-encoded BARF1 gene has oncogenic activity. We have recently reported that BARF1 is expressed as a latent gene in most nasopharyngeal carcinomas (NPC), suggesting that BARF1 may have an important role in NPC onc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b64fbc8de157dbfad4ac745eca3a2c84
https://doi.org/10.1158/0008-5472.c.6497636
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