Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Jaap Jan, Zwaginga"'
Autor:
Judith van Paassen, Pieter S. Hiemstra, Abraham C. van der Linden, Evert de Jonge, Jaap Jan Zwaginga, Robert J.M. Klautz, M. Sesmu Arbous
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-4 (2024)
Abstract Heart surgery may be complicated by acute lung injury and adult respiratory distress syndrome. Expression and release of mucins MUC5AC and MUC5B in the lungs has been reported to be increased in acute lung injury. The aim of our study was to
Externí odkaz:
https://doaj.org/article/85a5a2d329db427ebf1adc34251dbe84
Autor:
Sarah J. Valk, Camila Caram-Deelder, Rolf. H.H. Groenwold, Dorothea Evers, Karen M.K. de Vooght, Daan van de Kerkhof, Marielle J Wondergem, Nathalie C.V. Péquériaux, Francisca Hudig, Jaap Jan Zwaginga, Rutger A. Middelburg, Johanna G. van der Bom
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Previous studies found exposure to red blood cell transfusions from female donors who have been pregnant reduces survival in male patients compared to exposure to male donor products, but evidence is not consistent. We postulate the previously observ
Externí odkaz:
https://doaj.org/article/34a310a7f32d4eec8b291e50bc0467a1
Publikováno v:
Cells, Vol 13, Iss 11, p 941 (2024)
Regulatory T cells (Tregs) are essential to maintain immune homeostasis by promoting self-tolerance. Reduced Treg numbers or functionality can lead to a loss of tolerance, increasing the risk of developing autoimmune diseases. An overwhelming variety
Externí odkaz:
https://doaj.org/article/3b504bad04f845cdb87c640d1279ec51
Autor:
Pere Millat-Martinez, Arvind Gharbharan, Andrea Alemany, Casper Rokx, Corine Geurtsvankessel, Grigorios Papageorgiou, Nan van Geloven, Carlijn Jordans, Geert Groeneveld, Francis Swaneveld, Ellen van der Schoot, Marc Corbacho-Monné, Dan Ouchi, Francini Piccolo Ferreira, Pierre Malchair, Sebastian Videla, Vanesa García García, Anna Ruiz-Comellas, Anna Ramírez-Morros, Joana Rodriguez Codina, Rosa Amado Simon, Joan-Ramon Grifols, Julian Blanco, Ignacio Blanco, Jordi Ara, Quique Bassat, Bonaventura Clotet, Bàrbara Baro, Andrea Troxel, Jaap Jan Zwaginga, Oriol Mitjà, Bart J. A. Rijnders, CoV-Early study group, COnV-ert study group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5846cb1f73074a97acea76ceac3d412c
Autor:
A. J. Gerard Jansen, Vickie McDonald, Adrian Newland, Mervyn Morgan, Mieke Bastiaanse, Koo Wilson, Daniel Eriksson, Emma Geldman, Owen Daykin-Pont, Samantha Prince, Jaap Jan Zwaginga
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTObjective: Identify patient experience and preference towards thrombopoietin-receptor agonists (TPO-RAs) in treatment of immune thrombocytopenia (ITP) in the Netherlands.Methods: The Thrombopoietin-Receptor Agonist Patient experience (TRAPeze
Externí odkaz:
https://doaj.org/article/cfe21626ace94a01a52f7fe1eee7fca0
Autor:
Rik Paulus Bernardus Tonino, Mackenzie Tweardy, Stephan Wegerich, Rolf Brouwer, Jaap Jan Zwaginga, Martin Roelof Schipperus
Publikováno v:
Digital Biomarkers, Vol 6, Iss 3, Pp 117-126 (2022)
Introduction: Little is known if, and to what extent, outpatient red blood cell (RBC) transfusions benefit chronic transfusion-dependent patients. Costs, labour, and potential side effects of RBC transfusions cause a restrictive transfusion strategy
Externí odkaz:
https://doaj.org/article/cd259ba5dc134248a768e10cf7e91417
Autor:
Laura F. Ouboter, Marieke C. Barnhoorn, Hein W. Verspaget, Leonie Plug, Emma S. Pool, Karoly Szuhai, Lukas J.A.C. Hawinkels, Melissa van Pel, Jaap Jan Zwaginga, Dave Roelen, Frits Koning, M. Fernanda Pascutti, Andrea E. van der Meulen – de Jong
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
BACKGROUND Due to their immunoregulatory and tissue regenerative features, mesenchymal stromal cells (MSCs) are a promising novel tool for the management of ulcerative proctitis (UP). Here we report on a phase IIa clinical study that evaluated the im
Externí odkaz:
https://doaj.org/article/d46c7d397f5c473ea6322262d8153872
Autor:
Pere Millat-Martinez, Arvind Gharbharan, Andrea Alemany, Casper Rokx, Corine Geurtsvankessel, Grigorios Papageorgiou, Nan van Geloven, Carlijn Jordans, Geert Groeneveld, Francis Swaneveld, Ellen van der Schoot, Marc Corbacho-Monné, Dan Ouchi, Francini Piccolo Ferreira, Pierre Malchair, Sebastian Videla, Vanesa García García, Anna Ruiz-Comellas, Anna Ramírez-Morros, Joana Rodriguez Codina, Rosa Amado Simon, Joan-Ramon Grifols, Julian Blanco, Ignacio Blanco, Jordi Ara, Quique Bassat, Bonaventura Clotet, Bàrbara Baro, Andrea Troxel, Jaap Jan Zwaginga, Oriol Mitjà, Bart J. A. Rijnders, CoV-Early study group, COnV-ert study group
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Abstract Data on convalescent plasma (CP) treatment in COVID-19 outpatients are scarce. We aimed to assess whether CP administered during the first week of symptoms reduced the disease progression or risk of hospitalization of outpatients. Two multic
Externí odkaz:
https://doaj.org/article/98e3af5488ce46408e4660c90f2bdc2f
Autor:
Saeed Katiraei, Janna A. van Diepen, Luciana P. Tavares, Lisa R. Hoving, Amanda Pronk, Ineke Verschueren, Patrick C. N. Rensen, Jaap Jan Zwaginga, Sarantos Kostidis, Martin Giera, Mauro Teixera, Ko Willems van Dijk, Mihai G. Netea, Jimmy F. P. Berbée, Vanessa van Harmelen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Bone marrow transplantation (BMT) involves conditioning regimens which acutely induce side effects, including systemic inflammation, intestinal damage and shifts in the gut microbial composition, some of which may persist chronically. As the
Externí odkaz:
https://doaj.org/article/cc4da25ea14d4d3fafb29c84e5ac24db
Autor:
Tatjana Nikolic, Jessica S. Suwandi, Joris Wesselius, Sandra Laban, Antoinette M. Joosten, Petra Sonneveld, Dick Mul, Henk-Jan Aanstoot, John S. Kaddis, Jaap Jan Zwaginga, Bart O. Roep
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionRestoration of immune tolerance may halt progression of autoimmune diseases. Tolerogenic dendritic cells (tolDC) inhibit antigen-specific proinflammatory T-cells, generate antigen-specific regulatory T-cells and promote IL-10 production i
Externí odkaz:
https://doaj.org/article/6b30cbbe941d482d958e523b9eb75cf6