Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jaap G Neels"'
Autor:
Justin Chapman, Philip D Miles, Jachelle M Ofrecio, Jaap G Neels, Joseph G Yu, Jamie L Resnik, Jason Wilkes, Saswata Talukdar, Divya Thapar, Kristen Johnson, Dorothy D Sears
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13959 (2010)
Insulin resistance is manifested in muscle, adipose tissue, and liver and is associated with adipose tissue inflammation. The cellular components and mechanisms that regulate the onset of diet-induced insulin resistance are not clearly defined.We ini
Externí odkaz:
https://doaj.org/article/2364fd2af7e345e5bf026503469ef354
Autor:
Claudine Moratal, Joseph Murdaca, Coralie Cruzel, Amina Zamiti-Smondel, Nathan Heme, Florian Asarisi, Jaap G. Neels, Emile Ferrari, Giulia Chinetti
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 49, Iss , Pp 101309- (2023)
Background: Myocardial infarction (MI) is the primary cause of death in subjects with type 2 diabetes (T2D) and their in-hospital mortality after MI is still elevated compared with those without T2D. Therefore, it is of crucial importance to identify
Externí odkaz:
https://doaj.org/article/9b11076bd0494e89aa5d567757a41fca
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque. Furthermore, in the presence of
Externí odkaz:
https://doaj.org/article/daccc939019a42ea9942d92e98021987
Publikováno v:
Metabolites, Vol 13, Iss 3, p 457 (2023)
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipids in the vessel wall, leading to the formation of an atheroma and eventually to the development of vascular calcification (VC). Lipoproteins play a central ro
Externí odkaz:
https://doaj.org/article/59f82c0990f54ce3b12f8e36e268edc3
Autor:
Anne-Sophie Rousseau, Joseph Murdaca, Gwenaëlle Le Menn, Brigitte Sibille, Walter Wahli, Sébastien Le Garf, Giulia Chinetti, Jaap G. Neels, Isabelle Mothe-Satney
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Anti-inflammatory regulatory T cells (Tregs) are the most metabolically flexible CD4+ T cells by using both glycolysis and fatty acid oxidation (FAO) which allow them to migrate in tissues. With aging, Tregs accumulate in secondary lymphoid organs an
Externí odkaz:
https://doaj.org/article/5d23b3724f7a44f8be5665463357e65a
Autor:
Giulia Chinetti, Joseph Carboni, Joseph Murdaca, Claudine Moratal, Brigitte Sibille, Juliette Raffort, Fabien Lareyre, Elixène Jean Baptiste, Réda Hassen-Khodja, Jaap G. Neels
Publikováno v:
Metabolites, Vol 12, Iss 2, p 128 (2022)
Type 2 diabetes patients are less likely to develop an abdominal aortic aneurysm (AAA). Since macrophages play a crucial role in AAA development, we hypothesized that this decrease in AAA risk in diabetic patients might be due to diabetes-induced cha
Externí odkaz:
https://doaj.org/article/46ac6c53d1fa4e7d9afbf7b6761a4bbe
Autor:
Giulia Chinetti, Joseph Carboni, Joseph Murdaca, Claudine Moratal, Brigitte Sibille, Juliette Raffort, Fabien Lareyre, Elixène Jean Baptiste, Réda Hassen-Khodja, Jaap G. Neels
Publikováno v:
Metabolites. 12(2)
Type 2 diabetes patients are less likely to develop an abdominal aortic aneurysm (AAA). Since macrophages play a crucial role in AAA development, we hypothesized that this decrease in AAA risk in diabetic patients might be due to diabetes-induced cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3143574904225a322b92eba0def410
https://pubmed.ncbi.nlm.nih.gov/35208203
https://pubmed.ncbi.nlm.nih.gov/35208203
Autor:
Giulia Chinetti, Jaap G Neels
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6491, p 6491 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Vascular calcification is defined as an inappropriate accumulation of calcium depots occurring in soft tissues, including the vascular wall. Growing evidence suggests that vascular calcification is an actively regulated process, sharing similar mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2373fcd54dcf359ce503c550101d21
https://www.mdpi.com/1422-0067/22/12/6491
https://www.mdpi.com/1422-0067/22/12/6491
Autor:
Giulia Chinetti, I. Mothe-Satney, B. Sibille, Sébastien Le Garf, Philippe Fauque, Joseph Murdaca, Cyril Eininger, A.-S. Rousseau, Jaap G Neels
Publikováno v:
The FASEB Journal. 35
The decrease in the regulatory T cells (Tregs) population is highly involved in adipose tissue inflammation and insulin resistance in obesity. Tregs depend on fatty acids via β-oxidation for immunosuppressive function adapting their antioxidant syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fcb6277c2a8e24444eb267fe090961
https://doi.org/10.1096/fj.202001817rr
https://doi.org/10.1096/fj.202001817rr
Autor:
Audrey Laurain, Jaap G Neels, Thibault Florin, Claudine Moratal, Vincent L.M. Esnault, Mourad Naïmi, Giulia Chinetti, Guillaume Favre, Nicolas Chevalier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6009, p 6009 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Diabetic nephropathy (DN) is characterized by albuminuria, loss of renal function, renal fibrosis and infiltration of macrophages originating from peripheral monocytes inside kidneys. DN is also associated with intrarenal overactivation of the renin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f5396317b7d871c32a0eb9afe51e55
https://pubmed.ncbi.nlm.nih.gov/34199409
https://pubmed.ncbi.nlm.nih.gov/34199409