Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jaap Bosveld"'
Autor:
René Van Der Kwaak, Jaap Bosveld
Publikováno v:
Bio/technology (Nature Publishing Company). 10(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5302b4def4dc74e1540a065ba3b5c7bb
https://pubmed.ncbi.nlm.nih.gov/1368982
https://pubmed.ncbi.nlm.nih.gov/1368982
Publikováno v:
Biochemical and Biophysical Research Communications. 147:47-55
Murine interferon-alpha 1 and murine interferon-alpha 4 share 80% of their amino acids, yet the proteins differ considerably in their ability to protect mouse or hamster cells against viral infection. With the aim of localizing areas within these pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad977b971d294246db5c080ffa8212d2
https://doi.org/10.1016/s0006-291x(87)80085-2
https://doi.org/10.1016/s0006-291x(87)80085-2
Publikováno v:
Gene. 45:159-165
The coding regions of murine interferon-alpha (IFN-alpha) genes were combined with promoter and 3'-noncoding sequences from other eukaryotic genes. Transient expression of these fusion genes was achieved in monkey COS cells and in a mouse cell line (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985bee44f91eded9e4397560ac4a2036
https://doi.org/10.1016/0378-1119(86)90250-7
https://doi.org/10.1016/0378-1119(86)90250-7
Publikováno v:
The Journal of general virology. 67
Four natural murine interferon-alpha genes (MuIFN-alpha 1, -alpha 2, -alpha 4 and -alpha 6) and four hybrid genes (alpha 1 alpha 4, alpha 2 alpha 4, alpha 4 alpha 1 and alpha 4 alpha 2) were transiently expressed in monkey COS cells under the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d78d80edf15c6cfd442585d57dd73c8
https://pubmed.ncbi.nlm.nih.gov/3020159
https://pubmed.ncbi.nlm.nih.gov/3020159
Autor:
Margreet van Heuvel, Kor van As, Ellen C. Zwarthoff, Jan Trapman, Jaap Bosveld, A. C. P. Hekman
Publikováno v:
Biochemical and biophysical research communications. 164(1)
With the aim to assign differences in activity between murine interferon-alpha 1 and -alpha 4 to specific amino acids, we have constructed hybrid genes and analysed the antiviral properties of the corresponding hybrid proteins. The hybrid genes were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3cc58e3a61ad11214e900df8edf3d4
https://pubmed.ncbi.nlm.nih.gov/2508635
https://pubmed.ncbi.nlm.nih.gov/2508635