Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jaap A. Timmerman"'
Autor:
Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, Gema Muñoz González, Jaap A. Timmerman, Niels R.C. Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf, Antonio Luchicchi, Huibert D. Mansvelder, Niek P. van Til, Marjo S. van der Knaap, Marianna Bugiani
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Human brain experimental models recapitulating age- and disease-related characteristics are lacking. There is urgent need for human-specific tools that model the complex molecular and cellular interplay between different cell types to assess
Externí odkaz:
https://doaj.org/article/95f2002b28a24aafa6da02213860ae53
Autor:
Christina F. de Veij Mestdagh, Frank Koopmans, Jonathan C. Breiter, Jaap A. Timmerman, Pieter C. Vogelaar, Guido Krenning, Huibert D. Mansvelder, August B. Smit, Robert H. Henning, Ronald E. van Kesteren
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease worldwide and remains without effective cure. Increasing evidence is supporting the mitochondrial cascade hypothesis, proposing that loss of mitochondrial
Externí odkaz:
https://doaj.org/article/57d2e632022d4d42b3829a94237d7099
Autor:
Christina F. de Veij Mestdagh, Jaap A. Timmerman, Frank Koopmans, Iryna Paliukhovich, Suzanne S. M. Miedema, Maaike Goris, Rolinka J. van der Loo, Guido Krenning, Ka Wan Li, Huibert D. Mansvelder, August B. Smit, Robert H. Henning, Ronald E. van Kesteren
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Hibernation induces neurodegeneration-like changes in the brain, which are completely reversed upon arousal. Hibernation-induced plasticity may therefore be of great relevance for the treatment of neurodegenerative diseases, but remains larg
Externí odkaz:
https://doaj.org/article/79d911a2ec34496183b119acd53c6f51