Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice.

Autor: Sander S Rensen, Veerle Bieghs, Sofia Xanthoulea, Evi Arfianti, Jaap A Bakker, Ronit Shiri-Sverdlov, Marten H Hofker, Jan Willem Greve, Wim A Buurman

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52411 (2012)

BACKGROUND: Chronic inflammation and oxidative stress play fundamental roles in the pathogenesis of non-alcoholic steatohepatitis (NASH). Previously, we reported that myeloperoxidase (MPO), an aggressive oxidant-generating neutrophil enzyme, is assoc

Externí odkaz: https://doaj.org/article/9a7ef73a509242ab9918dec420fa7c62

The T1405N carbamoyl phosphate synthetase polymorphism does not affect plasma arginine concentrations in preterm infants.

Autor: Rob M J Moonen, Iballa Reyes, Giacomo Cavallaro, Gema González-Luis, Jaap A Bakker, Eduardo Villamor

Publikováno v: PLoS ONE, Vol 5, Iss 5, p e10792 (2010)

A C-to-A nucleotide transversion (T1405N) in the gene that encodes carbamoyl-phosphate synthetase 1 (CPS1) has been associated with changes in plasma concentrations of L-arginine in term and near term infants but not in adults. In preterm infants hom

Externí odkaz: https://doaj.org/article/30c0c80591454974a072085d31b1c0db

Abnormalities suggestive of latent tuberculosis infection on chest radiography; how specific are they?

Autor: Jonathan W. Uzorka, Lucia J.M. Kroft, Jaap A. Bakker, Erik W. van Zwet, Erik Huisman, Corine Prins, Cornelis J. van der Zwan, Tom H.M. Ottenhoff, Sandra M. Arend

Publikováno v: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 15, Iss , Pp - (2019)

Background: Several radiological features have been reported in association with latent tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study was to evaluate allegedly characteristic abnormalities on ches

Externí odkaz: https://doaj.org/article/22b75d04dfe947259a781e3846385bb3

Supplementary File from Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors

Autor: Diane van der Woude, René E.M. Toes, John B. Haanen, Tom W.J. Huizinga, Jaap A. Bakker, Annette Grummels, Els M.E. Verdegaal, Ellen H. Kapiteijn, Elisa A. Rozeman, Emma C. de Moel

Supplementary Figure S1 Supplementary Figure S2 Supplementary Table S1 Supplementary Table S2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03577eb135aaf4696279f9855c88f11
https://doi.org/10.1158/2326-6066.22536224.v1

Circumventing the Crabtree effect in cell culture

Autor: Michèle J. C. de Kok, Rob C. I. Wüst, Alexander F. Schaapherder, Jan H.N. Lindeman, Jaap A. Bakker, Melissa C. Zuiderwijk, Sylvia E. Le Dévédec

Publikováno v: de Kok, M J C, Schaapherder, A F, Wüst, R C I, Zuiderwijk, M, Bakker, J A, Lindeman, J H N & Le Dévédec, S E 2021, ' Circumventing the Crabtree effect in cell culture : A systematic review ', Mitochondrion, vol. 59, pp. 83-95 . https://doi.org/10.1016/j.mito.2021.03.014
Mitochondrion, 59, 83-95. ELSEVIER SCI LTD
Mitochondrion, 59, 83-95. Elsevier BV

Metabolic reprogramming and mitochondrial dysfunction are central elements in a broad variety of physiological and pathological processes. While cell culture established itself as a versatile technique for the elaboration of physiology and disease, s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89d2296fdc809e1cfc827eb3b503ee1
https://doi.org/10.1016/j.mito.2021.03.014